#tfus — Public Fediverse posts

WIRED: Her brain was broken. It was fixed with sound - not a scalpel https://www.wired.com/story/brain-focused-ultrasound/ (archived at https://archive.ph/lJOwD); #tFUS #neuroscience

tFUS is not without unknowns and risks: "Last year, about a month after Erin's procedure, a 44-year-old volunteer in the WVU trial suffered a brain injury in the MRI machine. While researchers were increasing the #ultrasound's intensity, the man suddenly became unresponsive."

"Scans showed that the man suffered tiny hemorrhages in and around his nucleus accumbens."

Calibrated simulations for dynamic focusing of ultrasound through the temporal window https://www.medrxiv.org/content/10.64898/2026.01.27.26344890v1 #ultrasound #BCI #safety #tFUS

Chinese company #Gestala, founded and led by Phoenix Peng, aims to achieve whole-brain reading, writing, and modulation through phased-array #ultrasound https://www.gestala.com #tFUS #BCI #NeuroTech

Ultrasound system for precise neuromodulation of human deep brain circuits https://www.nature.com/articles/s41467-025-63020-1 phased-array #tFUS #TUS #FUS #BCI #NeuroTech

"Experiments demonstrated selective modulation of the lateral geniculate nucleus (#LGN) and connected visual cortex regions. Participants showed significantly increased visual cortex activity during concurrent TUS and visual stimulation, with high cross-individual reproducibility."

Transcranial focused ultrasound for identifying the neural substrate of conscious perception https://arxiv.org/abs/2507.08517 Indeed I see long-term potential for phased-array tFUS as a visual prosthesis for the late-blind. The company Nudge is developing a phased-array tFUS helmet. #tFUS

Prediction: interest in electrode-based BCIs will wane (aside from niches), as non-implantable ("non-invasive") phased array focused ultrasound will take over for both brain stimulation and measuring brain activity https://www.cell.com/neuron/fulltext/S0896-6273(20)30703-0 (2020) #BCI #NeuroTech #FUS #tFUS #fUSI #neuroscience

Now if, say, #tFUS #neuromodulation can boost visualization of https://youtube.com/watch?v=7jFJ_IXzwKI while awake, then we are in business... (use stereo headphones); #Woke #BCI #NeuroTech

FWIW, the company #Prophetic is trying to non-invasively induce lucid dreams https://www.prophetic.com #BCI #NeuroTech #tFUS #neuromodulation

I have often been asked about mechanisms for focused ultrasound neuromodulation.

Here is Figure 2 from this 2022 review paper by Dell'Italia, Sanguinetti, Monti, Bystritsky, and Reggente proposing mechanisms: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081930/

#tfus #focusedultrasound #neuroscience #neuromodulation

The future of brain–machine interfaces is optical https://www.nature.com/articles/s41928-023-00926-y via @kordinglab; Did anyone say transcranial focused #ultrasound? #BCI #BMI #NeuroTech #TFUS #FUS #neuroscience