#tecovirimat — Public Fediverse posts

[Correspondence] #Mpox virus in #human #breastmilk and #tecovirimat pharmacokinetics: implications for #postnatal #transmission https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00138-6/fulltext?rss=yes

#Tecovirimat is #safe but #ineffective as #treatment for clade II #mpox, https://etidiohnew.blogspot.com/2025/03/tecovirimat-is-safe-but-ineffective-as.html

#Antiviral activity of #tecovirimat against #monkeypox virus clades 1a, 1b, 2a, and 2b, https://etidiohnew.blogspot.com/2025/01/antiviral-activity-of-tecovirimat.html

Source: Emerging Infectious Diseases Journal, https://wwwnc.cdc.gov/eid/article/30/11/24-1331_article

Abstract
We report a case of persistent disseminated mpox evolving over >6 months in an HIV/hepatitis B virus co-infected patient in France who had <200 CD4+ cells/mm3, pulmonary and hepatic necrotic lesions, persistent viremia, and nasopharyngeal excretion. Clinical outcome was favorable after 90 days of tecovirimat treatment and administration of human vaccinia immunoglobulins.

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https://etidioh.wordpress.com/2024/10/21/mpox-hepatic-and-pulmonary-lesions-in-hiv-hepatitis-b-virus-co-infected-patient-france/

#abstract #antivirals #france #hepatitisB #HIVAIDS #mpox #research #tecovirimat

Notes from the Field: #Mpox #Cluster Caused by #Tecovirimat – #Resistant Monkeypox Virus – Five States, October 2023-February 2024

Source: US National Library of Medicine, AbstractThe antiviral drug tecovirimat* has been used extensively to treat U.S. mpox cases since the start of a global outbreak in 2022. Mutations in the mpox viral protein target (F13 or VP37) that occur during treatment can result in resistance to tecovirimat† (1,2). CDC and public health partners…

https://etidioh.wordpress.com/2024/10/11/notes-from-the-field-mpox-cluster-caused-by-tecovirimat-resistant-monkeypox-virus-five-states-october-2023-february-2024/

Mpox Disease: The Antiviral Tecovirimat (TPOXX) Found Ineffective in Clinical Trial
The monkeypox virus (MPXV), called so because of its first discovery in monkeys kept in research facility in Denmark, is closely related to variola...........
#antiviral #AntiviralDrug #DRCongo #monkeypox #monkeypoxvirus #Mpox #MPXV #Tecovirimat
Umesh Prasad

https://www.scientificeuropean.co.uk/medicine/mpox-disease-the-antiviral-tecovirimat-tpoxx-found-ineffective-trial-in-dr-congo/

#Tecovirimat #Resistance in #Mpox Patients, #USA, 2022–2023, Emerg Infect Dis.: https://wwwnc.cdc.gov/eid/article/29/12/23-1146_article?ACSTrackingID=USCDC_333-DM115592&ACSTrackingLabel=Latest%20Expedited%20Articles%20-%20Emerging%20Infectious%20Diseases%20Journal%20-%20October%2019%2C%202023&deliveryName=USCDC_333-DM115592 #antivirals #drugs #EIDs