#spinabifida — Public Fediverse posts

What went right this week: the good news that matters

https://web.brid.gy/r/https://www.positive.news/society/good-news-stories-from-week-10-of-2026/

Sei feti con spina bifida hanno ricevuto un cerotto di cellule staminali ancora prima di nascere. Il trial CuRe della UC Davis, pubblicato su Lancet, conferma: è sicuro, nessun tumore, nessuna complicanza. Uno di quei bambini oggi ha 4 anni, cammina e corre. Fase 1 superata! È una bella notizia: ora si parte con la Fase 2 e 35 pazienti. "Eppur si muove", la spina bifida ha gli anni contati?

https://www.futuroprossimo.it/2026/02/spina-bifida-le-staminali-sul-feto-funzionano-il-primo-trial-dice-si

#futuroprossimo #spinabifida #staminali

UNH men’s basketball team signs 13-year-old to the Wildcats https://www.rawchili.com/nba/350375/ #Apple|GooglePlay #Basketball #BasketballTeam #diabetes #download #FreeWmurApp #go #Gustafson #impact #NewHampshire #NewHampshireMan #NewTeammateFridayAfternoon #NH #SpinaBifida #subscribe #type #TypeOneDiabetes #UNH #UnhMan #wildcats #YoutubeChannel

You may recall Josh Turek's name from his playing wheelchair basketball professionally around the world and in four Paralympic Games, winning two gold medals.

Since Jan 2023 he’s served in Iowa state legislature. And today Josh Turek launched his U.S. Senate campaign. https://youtu.be/kCD3vVVAa7U?si=WypRd6Syxsxca7tZ

fyi: Duck Player “lets you watch videos on YouTube without privacy-invading ads, and keeps what you watch from impacting your recommendations.‌” https://duckduckgo.com/duckduckgo-help-pages/duck-player/

https://turek4iowa.com/about/

#DisabilityIsNotABadThing #Paralympics #Underdog #JoshTurek #Iowa #USsenate #SpinaBifida #AgentOrange #TomHarkin #AmericansWithDisabilitiesAct

You may recall Josh Turek's name from his playing wheelchair basketball professionally around the world and in four Paralympic Games, winning two gold medals.

Since Jan 2023 he’s served in Iowa state legislature. And today Josh Turek launched his U.S. Senate campaign. https://youtu.be/kCD3vVVAa7U?si=WypRd6Syxsxca7tZ

fyi: Duck Player “lets you watch videos on YouTube without privacy-invading ads, and keeps what you watch from impacting your recommendations.‌” https://duckduckgo.com/duckduckgo-help-pages/duck-player/

https://turek4iowa.com/about/

#DisabilityIsNotABadThing #Paralympics #Underdog #JoshTurek #Iowa #USsenate #SpinaBifida #AgentOrange #TomHarkin #AmericansWithDisabilitiesAct

You may recall Josh Turek's name from his playing wheelchair basketball professionally around the world and in four Paralympic Games, winning two gold medals.

Since Jan 2023 he’s served in Iowa state legislature. And today Josh Turek launched his U.S. Senate campaign. https://youtu.be/kCD3vVVAa7U?si=WypRd6Syxsxca7tZ

fyi: Duck Player “lets you watch videos on YouTube without privacy-invading ads, and keeps what you watch from impacting your recommendations.‌” https://duckduckgo.com/duckduckgo-help-pages/duck-player/

https://turek4iowa.com/about/

#DisabilityIsNotABadThing #Paralympics #Underdog #JoshTurek #Iowa #USsenate #SpinaBifida #AgentOrange #TomHarkin #AmericansWithDisabilitiesAct

You may recall Josh Turek's name from his playing wheelchair basketball professionally around the world and in four Paralympic Games, winning two gold medals.

Since Jan 2023 he’s served in Iowa state legislature. And today Josh Turek launched his U.S. Senate campaign. https://youtu.be/kCD3vVVAa7U?si=WypRd6Syxsxca7tZ

fyi: Duck Player “lets you watch videos on YouTube without privacy-invading ads, and keeps what you watch from impacting your recommendations.‌” https://duckduckgo.com/duckduckgo-help-pages/duck-player/

https://turek4iowa.com/about/

#DisabilityIsNotABadThing #Paralympics #Underdog #JoshTurek #Iowa #USsenate #SpinaBifida #AgentOrange #TomHarkin #AmericansWithDisabilitiesAct

You may recall Josh Turek's name from his playing wheelchair basketball professionally around the world and in four Paralympic Games, winning two gold medals.

Since Jan 2023 he’s served in Iowa state legislature. And today Josh Turek launched his U.S. Senate campaign. https://youtu.be/kCD3vVVAa7U?si=WypRd6Syxsxca7tZ

fyi: Duck Player “lets you watch videos on YouTube without privacy-invading ads, and keeps what you watch from impacting your recommendations.‌” https://duckduckgo.com/duckduckgo-help-pages/duck-player/

https://turek4iowa.com/about/

#DisabilityIsNotABadThing #Paralympics #Underdog #JoshTurek #Iowa #USsenate #SpinaBifida #AgentOrange #TomHarkin #AmericansWithDisabilitiesAct

"Our research identifies specific steps in embryogenesis that contribute to spina bifida," said senior study author Dr. Joseph Gleeson, a professor at Rady Children's Institute for Genomic Medicine and the University of California, San Diego. "This is a major step forward in understanding why this condition occurs and how we might one day prevent it."

#genetics #research #science #biology #SpinaBifida

https://www.labroots.com/trending/cell-and-molecular-biology/28807/insights-causes-spina-bifida

Researchers Reveal New Details of the Genetics of Spina Bifida

"This finding really got us excited ..." said Dr Keng Ioi Vong, PhD.

#SpinaBifida #BirthDefects #genetics #biology #research #Science

https://www.labroots.com/trending/genetics-and-genomics/27123/researchers-reveal-details-genetics-spina-bifida

@verdantsquare

Interesting.

From the original research article*:

"...we inferred that the AluY insertion may mediate an alternative splicing (AS) event of the hominoid TBXT in an unusual way. This AluY element is not inserted in the vicinity of a splice site; instead, it is >500 bp from exon 6 of TBXT, the nearest coding exon (Fig. 1b). As such, it would not be expected, by itself, to lead to an AS event, as found for other individual intronic Alu elements near exon boundaries that directly affect splicing32,33,34. However, we noted the presence of another Alu element (AluSx1) in the reverse orientation in intron 5 of TBXT that is shared among all monkeys and apes (simians). Together, the AluY and AluSx1 elements form an exon-flanking inverted repeat pair (Fig. 1b). We therefore posited that during transcription, the hominoid-specific AluY element pairs with the simian-shared AluSx1 element to form a stem–loop structure in TBXT pre-mRNA and traps exon 6 in the loop (Fig. 1c). An inferred model of the RNA secondary structure supported the interaction between these two Alu elements35 (Extended Data Fig. 2). The secondary structure of the transcript may conjoin the splice donor and receptor site of exons 5 and 7, respectively, and promote the skipping of exon 6, thereby leading to a hominoid-specific and in-frame AS isoform: TBXTΔexon6 (Fig. 1c). "

* https://www.nature.com/articles/s41586-024-07095-8

#Genetics #AlternativeSplicing #SpinalCord #NeuralTubeDefects
#SpinaBifida #TetheredCord

‘A landmark step’: how pioneering foetal surgery is transforming lives - https://www.theguardian.com/society/2023/jan/08/landmark-step-pioneering-foetal-surgery-transforming-lives hopeful stuff "procedure that can radically improve outcomes for babies with #SpinaBifida" #medicine

I am so sick of seeing people try to defend Elon Musk's toxic behavior by pointing to his autism.

Let me be clear as someone with cerebral palsy and ADHD: Autism/neurodivergence/disability is never an excuse for malicious actions. Plenty of people are autistic without being assholes.

#disability #disabled #neurodivergent #neurodiversity #autistic #autism #CerebralPalsy #SpinaBifida #TBI #dementia #SpinalCordInjury #ToxicMasculinity #ElonMusk #Elon #Twitter #BirdSite #SocialMedia

So happy for our patients in this fetal surgery #stemcell trial for #spinabifida. My amazing colleague Dr. Diana Farmer has worked toward this for decades, and the cell manufacturing was done in our GMP facility at UC Davis. Spoiler alert- the babies are born kicking their feet! A feel-good story for the holidays.
https://youtube.com/watch?v=TGvHRqsopQo&feature=share