#spermatogenesis — Public Fediverse posts

A preprint from our collaboration with Drs. Mayo and Sainz from Univ. of Oviedo. Great work, Dr. Cepas-López and Ms. García-Soler! It was a pleasure to work with you in this project!
http://dx.doi.org/10.2139/ssrn.6753758
#AnimalReproduction #mouse #OxidativeStress #spermatogenesis

Safeguarding spermatogenesis from retrotransposon insertions by forming ecDNA.

#Transposons #Retrotransposons #ExtrachromosomalCircularDNA #ecDNA #Spermatogenesis #Drosophila #Preprint

https://www.biorxiv.org/content/10.1101/2025.05.11.653319v1

Safeguarding spermatogenesis from retrotransposon insertions by forming ecDNA.

#Transposons #Retrotransposons #ExtrachromosomalCircularDNA #ecDNA #Spermatogenesis #Drosophila #Preprint

https://www.biorxiv.org/content/10.1101/2025.05.11.653319v1

28-Aug-2024
Shocking revelation: an electrically-activated protein regulates #spermatogenesis
Researchers from Osaka University find that a voltage-dependent phosphatase is crucial for translating electrical signals into chemical signals that promote proper #sperm maturation

Of course it takes a spark to make the love happen ...

https://www.eurekalert.org/news-releases/1056061 #science #physiology #proteins #nanoworld

AMG-1/SLRP-1 is required for #spermatogenesis in #C_elegans: Study.

#RNAP

https://phys.org/news/2023-07-amg-1slrp-required-spermatogenesis-elegans.html

@jaclynmacrae

Some Long Covid symptoms, e.g., alcohol intolerance, could be due to lowered activity of aldehyde dehydrogenase, particularly ALDH2. I submitted a related hypothesis to the Patient-Led Hypothesis Generation Panel which provides background & refs (1).

Inhibition of aldehyde dehydrogenase causes lower sperm count & has been investigated as a means of male birth control (2).

1- https://docs.google.com/document/d/1XBe3xkZLUtcTUZjd07nH97jjL9QR5Vt3YS08zo7WpOY/edit?usp=sharing

2- https://www.bloomberg.com/news/features/2017-08-03/why-we-can-t-have-the-male-pill

#LongCovid #ALDH2 #RetinoicAcid #spermatogenesis