home.social

#signaling — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #signaling, aggregated by home.social.

  1. 🥴 Ah yes, the riveting tale of Claude's ever-changing moral compass, as predictable as a weather vane in a #hurricane. 🌪️ Let us bask in the glow of corporate virtue-signaling while Claude tries to decode the profound mysteries of small talk. 🙄
    anthropic.com/research/claude- #corporatevirtue #signaling #moralcompass #smalltalk #tales #HackerNews #ngated

  2. Oh, look! A website where you can hover over blinking dots to "remember" 72,000 lives, as if they were just pixels on a screen. Because nothing says meaningful homage like a digital version of Minesweeper with a side of ✨virtue signaling✨.
    bkhmsi.github.io/i-am-not-a-nu #digitalmemorials #virtue #signaling #onlinehomage #techcritique #pixelart #72000lives #HackerNews #ngated

  3. Unusual #ubiquitin #ligase interplay in #Hippo #signaling:
    Bin Zhao, Xin-Hua Feng and colleagues Zhejiang University show that #HERC3 blocks #YAP/#TAZ recognition and degradation via #SCF-#betaTrCP independent of its own E3 activity
    embopress.org/doi/10.15252/emb

  4. CW: Combinatorial interpretation of BMP and WNT allows BMP to act as a morphogen in time but not in concentration.

    "[...] varying the duration of #BMP #signaling leads to either pluripotent, mesodermal, and extraembryonic states, while varying the concentration does not cause efficient mesodermal differentiation at any dose [...] appropriately timed pulse of BMP induces #hPSCs to a mesodermal fate more efficiently that sustained signaling at any concentration. [...] this effect is due to a combinatorial interpretation of the applied BMP signal and induced endogenous #Wnt signaling."
    biorxiv.org/content/10.1101/20
    #DevBio #CellFate #GermLayers #morphogens #Differentiation