#schistosomiasis — Public Fediverse posts

Vernachlässigte Tropenkrankheiten (NTDs) stellen auch europäische Gesundheitssysteme vor Herausforderungen.

Im Interview erklärt Dr. Daniela Fusco vom Bernhard-Nocht-Institut für Tropenmedizin, warum der Zugang zu Arzneimitteln gegen NTDs auch hierzulande problematisch ist und weshalb das Thema mehr Aufmerksamkeit braucht.

https://bukopharma.de/pharmabrief/pharma-brief-3-2026-preise-fuer-krebsmedikamente-ntds-und-entwicklungshilfe/tropenkrankheiten-europaeische-mangelwirtschaft/

#NTDs #Schistosomiasis #Arzneimittelzugang

'Proportions of memory T cells and expression of their associated cytokines in lymph nodes of mice infected with Echinococcus multilocularis' - a #Research article in the Chinese Journal of #Schistosomiasis Control on #ScienceOpen: https://www.scienceopen.com/document?vid=70b368f5-8810-4e57-8707-0feb6546725d

Kennt ihr schon unsere #Podcast-Reihe zu #NTDs? Hört spannende Geschichten zu #Chagas, #Schistosomiasis, #Tollwut, #Schlangenbissen und zum #Trachom 👇
https://www.youtube.com/playlist?list=PLxgSnvr1t0xClIy6YGDO14swqCMnEK5h4

❓Can we confirm resistance to a drug used for the past 30+ years against #Schistosomiasis: a neglected tropical #disease affecting >200 million people (45% children)?

🇬🇭#Researchers from Ghana share their Research Idea in our journal: https://doi.org/10.3897/rio.10.e120899 #WorldHealthDay

Noch vor Ostern werden wir Euch die dritte Podcast Folge zu #NTDs präsentieren, dieses Mal geht´s um #Tollwut. Seid gespannt🥳
Bis dahin hört doch mal in unsere bisherigen Folgen zu #Chagas und #Schistosomiasis rein⏯️🎧🎈👇
https://tinyurl.com/yl7l35gw

Dem Thema #Schistosomiasis widmet sich auch unsere neue Podcastfolge! 🎧
Mit dabei: Daniela Fusco, die am BNITM eine Arbeitsgruppe in der Abteilung für #Infektionsepidemiologie leitet und unter anderem Projekte auf #Madagaskar durchführt.
Wir freuen uns, wenn Ihr reinhört! ⬇️
https://www.youtube.com/watch?v=fwcRq4lpBqY

New preprint! Proud to be part of this important study on the #genome of an African #snail vector that transmits #parasites causing #schistosomiasis, one of the most prevalent #NeglectedTropicalDiseases affecting >200 million people. I know, you've seen genome papers before, but wait there's more! We actually sequenced several inbred lines, allowing us to find and characterize highly variable genes of possible immune relevance.
🐌🧬🐌🧬🐌🧬🐌🧬🐌🧬
https://www.biorxiv.org/content/10.1101/2023.11.01.565203v1

Check out this thread if you are interested in the interactions among #disease, #evolution, #socialjustice, #climatechange, #genomics, etc., especially #malaria, #schistosomiasis, #filariasis, and other #tropicaldiseases caused by #parasites.

Looking forward to #TropMed23 next week in Chicago! I'll be talking about #GWAS in #snails revealing clues to fight #schistosomiasis. If you're attending, find me and say hi! #ASTMH

Urinary Schistosomiasis

https://www.nejm.org/doi/full/10.1056/NEJMicm2300207

> Images in Clinical Medicine from The New England Journal of Medicine
#IDMastodon #MedMastodon #medicine #infectiousdiseases #tropical #bladder #schistosomiasis

Sommerlektüre: Unser #Pharmabrief 4-5/2023

Zur #Insulin'herstellung, #Schistosomiasis und unserer Vortragsreise & Konferenz zu #Pandemie'folgen mit @SUE_NRW 👇👀

https://bukopharma.de/images/pharmabrief/2023/Phbf2023_04_05.pdf

A difficult part of controlling some #parasitic #diseases is their complex #lifecycle with multiple #hosts.

But this can also be used against them by controlling their hosts.

This article outlines a fantastic #schistosomiasis #management strategy in which #snail #habitat (#vegetation) was reduced.

Benefits:
-disease reduction
-better access to water
-compost for #agriculture
-animal feed

Article 🔗 https://www.nature.com/articles/s41586-023-06313-z

Explainer 🔗 https://www.nature.com/articles/d41586-023-02178-4

Podcast 🔗 https://www.nature.com/articles/d41586-023-02362-6

AAAS: "'Win-win-win' strategy reduces dangerous parasite infections in African villages." A parasitic flatworm in the genus Schistosoma in Africa infects millions, causing pain, weakness + in children failure to thrive plus cognitive dysfunction. Some peope get liver disease or cancer. "Now, researchers have shown in a trial in Senegal that a simple intervention could reduce the risk of infection and break the resulting spiral of poverty and disease." Harvesting aquatic plants removes habitat for the snails carrying the parasite, which slashes rates of schistosomiasis, benefiting farmers with the vegatation being used for fertilizer + fodder for animals. Infected people pass schistosome eggs in their urine or stool, depending on species. The eggs infect certain snail species, which release second-stage larvae which can burrow through intact human skin, completing the cycle. The drug praziquantel can knock down the disease burden in people, but rapid reinfection often occurs. In the randomized, controlled trial,  residents of 8 villages in Senegal were paid to remove water plants every 3 months for 3 yrs. The number of snails was reduce eightfold compared to control villages. "And the percentage of schoolchildren infected with one flatworm parasite, Schistosoma mansoni, was 23.5% in sites where the vegetation was removed, whereas it was 31.5% in control villages, Rohr and colleagues report in Nature." The composted plants increased yields of papper + onions, 2 local crops. As for fodder, goats were not interested, but sheep, donkey + cattle were happy to partake. As a former president told us, this represents so much winning that we should be sick + tired of all the winning.   #schistosomiasis    #parasitology    #winning

A new study of ancient Egyptian child mummies reveals that they suffered from a parasitic disease called schistosomiasis. The disease is caused by worms that infect the urinary tract or the intestines after contact with contaminated water. Schistosomiasis is still a major public health problem in many parts of the world, affecting more than 250 million people.

#Egypt #Mummies #Schistosomiasis

https://www.sciencealert.com/egyptian-child-mummies-reveal-high-prevalence-of-an-ancient-sickness

#Schistosomiasis is a neglected tropical disease (#NTD); one diagnosis is finding the parasite egg in urine. It can be as low as one egg in one liter. We can use our microfluidic to find and identify the egg using cheap microscopes.

How cheap, you ask? Same question I asked @beniroquai: “what’s the cheapest microscope we can do for this detection?” And so the #ESP32 #microscope was born. Less than 10€, mostly 3D printed, wifi, and fully open: https://github.com/Matchboxscope/Matchboxscope/blob/master/Matchboxscope.md

I have many ongoing projects in #genomics and #evolution of #diseases caused by #parasites. One area concerns #snails that transmit #schistosomes which infect >200 million people. I want to find snail #genes that affect their resistance to infection by parasites, and study how these genes naturally vary and evolve. If we can block infection in wild snails, we could stop the spread of deadly #schistosomiasis.
🐌