home.social

#reproaging — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #reproaging, aggregated by home.social.

fetched live
  1. Bérénice A. Benayoun @[email protected] ·

    We are glad that the editorial team at #TranslationalMedicineOfAging and the peer-reviewers agreed that these were important results to disseminate to the #ReproAging research community.
    We also thank @[email protected] for supporting our work! @[email protected] 5/5

    #reproaging #translationalmedicineofaging
  2. Bérénice A. Benayoun @[email protected] ·

    As noted before, although we are disappointed that these mice cannot be used to effectively model menopausal states, we hope our observations will be useful to the #ReproAging community and avoid unnecessary waste of animals/time/resources by other labs. 4/5

    #reproaging
  3. Bérénice A. Benayoun @[email protected] ·

    We confirmed that the #KOMP allele should correspond to a null allele (confirmed by Sanger🧬), but it seems that the wild-type allele is compensating in this 🐁 strain, leading to normal Fshr expression, ovarian function and absence of #ReproAging phenotype.
    3/5

    #reproaging #komp
  4. Bérénice A. Benayoun @[email protected] ·

    Previous tweetorial on the preprint below - briefly, we did not observe any indication of accelerated #ReproAging in the #KOMP Fshr allele, contrary to previous work (on a distinct allele), based on breeding, endocrine markers and histology.
    2/5 twitter.com/BBParis1984/status

    #komp #reproaging
  5. Bérénice A. Benayoun @[email protected] ·

    We hope that this study will be a useful resource for #ReproAging research and #TE Biology!
    We also thank @[email protected], our🐠🧙‍♂️#AriAdler and talented #qbio and #mcb undergrad #AlanXu and #KatelynHsu for their help on this study! 9

    #katelynhsu #alanxu #mcb #qbio #ariadler #te
  6. Bérénice A. Benayoun @[email protected] ·

    We were curious about how #TEs would be impacted by #ReproAging, since #TE reactivation is frequent during somatic aging. Because of transgenerational mutagenic potential, dedicated safeguards evolved to keep #TEs in check in the #germline, notably through the #PIWI pathway. 3/n

    #piwi #germline #te #reproaging #tes
  7. Bérénice A. Benayoun @[email protected] ·

    Really excited to share our latest work, on deciphering #TE control 🧬 during #ReproAging ♀️♂️ in #AfricanTurquoiseKillifish 🐟 [ATK], online today at @[email protected]! This was spearheaded by talented #DrBryanTeefy in the lab. @[email protected] A 🧵 1/n
    genome.cshlp.org/content/early

    #drbryanteefy #africanturquoisekillifish #reproaging #te