#reelin — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #reelin, aggregated by home.social.
-
A protein called #Reelin keeps popping up in brains that resist aging and #Alzheimer’s https://www.npr.org/sections/shots-health-news/2024/07/29/g-s1-13519/alzheimers-protein-reelin-brain-aging-amyloid-tau-memory
-
Resilience to autosomal dominant Alzheimer’s disease in a Reelin-COLBOS heterozygous man
The male remained cognitively intact until 67 years of age despite carrying a PSEN1-E280A mutation. He had extremely elevated amyloid plaque burden and limited entorhinal Tau tangle burden.
He was heterozygous for a rare variant in RELN showing stronger ability to reduce human Tau phosphorylation in a knockin mouse.#Biomedicine #Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Alzheimer #Tau #Reelin #ApoE #Dementia #Neurogenetics
-
#generic #mutations could guide development of new #Alzheimers meds
#medicine #research #entorhinalCortex #TauTangles #TauBuildup #reelin