#receptors — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #receptors, aggregated by home.social.
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#Bovine #H5N1 #influenza viruses have adapted to more efficiently use #receptors abundant in #cattle, https://etidiohnew.blogspot.com/2026/04/bovine-h5n1-influenza-viruses-have.html
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News from Leibniz research: #Bitter #Taste #Receptors at the Interface Between #Nutrition, the #Endocrine System, and #Health https://www.leibniz-lsb.de/en/press-public-relations/translate-to-englisch-pm-20260128-pressemitteilung-bittergeschmacksrezeptoren-ernaehrung-hormonsystem-gesundheit
https://nachrichten.idw-online.de/2026/01/28/bitter-taste-receptors-at-the-interface-between-nutrition-the-endocrine-system-and-health -
#RaphaelMechoulam, the father of 🌱 #cannabis #research, passed away on March 10, 2023, at 92 years of age. In early 1960, he was the first to reveal the structure of #cannabidiol (#CBD) and delta 9-#tetrahydrocannabinol (#THC), molecules now used worldwide as #medicine.1,2 In addition, Professor #Mechoulam and his research group identified the #endocannabinoidsystem, a #biologicalsystem with #endogenous #neurotransmitters that bind to specific #receptors ... https://pmc.ncbi.nlm.nih.gov/articles/PMC10288473/
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#RaphaelMechoulam, the father of 🌱 #cannabis #research, passed away on March 10, 2023, at 92 years of age. In early 1960, he was the first to reveal the structure of #cannabidiol (#CBD) and delta 9-#tetrahydrocannabinol (#THC), molecules now used worldwide as #medicine.1,2 In addition, Professor #Mechoulam and his research group identified the #endocannabinoidsystem, a #biologicalsystem with #endogenous #neurotransmitters that bind to specific #receptors ... https://pmc.ncbi.nlm.nih.gov/articles/PMC10288473/
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#RaphaelMechoulam, the father of 🌱 #cannabis #research, passed away on March 10, 2023, at 92 years of age. In early 1960, he was the first to reveal the structure of #cannabidiol (#CBD) and delta 9-#tetrahydrocannabinol (#THC), molecules now used worldwide as #medicine.1,2 In addition, Professor #Mechoulam and his research group identified the #endocannabinoidsystem, a #biologicalsystem with #endogenous #neurotransmitters that bind to specific #receptors ... https://pmc.ncbi.nlm.nih.gov/articles/PMC10288473/
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#RaphaelMechoulam, the father of 🌱 #cannabis #research, passed away on March 10, 2023, at 92 years of age. In early 1960, he was the first to reveal the structure of #cannabidiol (#CBD) and delta 9-#tetrahydrocannabinol (#THC), molecules now used worldwide as #medicine.1,2 In addition, Professor #Mechoulam and his research group identified the #endocannabinoidsystem, a #biologicalsystem with #endogenous #neurotransmitters that bind to specific #receptors ... https://pmc.ncbi.nlm.nih.gov/articles/PMC10288473/
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#RaphaelMechoulam, the father of 🌱 #cannabis #research, passed away on March 10, 2023, at 92 years of age. In early 1960, he was the first to reveal the structure of #cannabidiol (#CBD) and delta 9-#tetrahydrocannabinol (#THC), molecules now used worldwide as #medicine.1,2 In addition, Professor #Mechoulam and his research group identified the #endocannabinoidsystem, a #biologicalsystem with #endogenous #neurotransmitters that bind to specific #receptors ... https://pmc.ncbi.nlm.nih.gov/articles/PMC10288473/
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16-Sep-2025
Better understanding of #bitter #taste receptors: An AlphaFold3-based structure study
Researchers use an advanced AI-based prediction model, #AlphaFold 3, to predict the structure of human bitter taste #receptors
https://www.eurekalert.org/news-releases/1098406 -
16-Sep-2025
Better understanding of #bitter #taste receptors: An AlphaFold3-based structure study
Researchers use an advanced AI-based prediction model, #AlphaFold 3, to predict the structure of human bitter taste #receptors
https://www.eurekalert.org/news-releases/1098406 -
16-Sep-2025
Better understanding of #bitter #taste receptors: An AlphaFold3-based structure study
Researchers use an advanced AI-based prediction model, #AlphaFold 3, to predict the structure of human bitter taste #receptors
https://www.eurekalert.org/news-releases/1098406 -
16-Sep-2025
Better understanding of #bitter #taste receptors: An AlphaFold3-based structure study
Researchers use an advanced AI-based prediction model, #AlphaFold 3, to predict the structure of human bitter taste #receptors
https://www.eurekalert.org/news-releases/1098406 -
#H3N2 #influenza virus #tropism shifts to glycan #receptors on tracheal ciliated cells, https://etidiohnew.blogspot.com/2025/09/h3n2-influenza-virus-tropism-shifts-to.html
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#Sialic Acid #Receptors in #Human Mammary Tissue: Implications for #Infection with Novel #Influenza Strains, https://etidiohnew.blogspot.com/2025/08/sialic-acid-receptors-in-human-mammary.html
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Pregnant Dairy #Heifers Express #Influenza A Virus #Receptors in the Mammary #Gland, https://etidiohnew.blogspot.com/2025/05/pregnant-dairy-heifers-express.html
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Pregnant Dairy #Heifers Express #Influenza A Virus #Receptors in the Mammary #Gland, https://etidiohnew.blogspot.com/2025/05/pregnant-dairy-heifers-express.html
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Pregnant Dairy #Heifers Express #Influenza A Virus #Receptors in the Mammary #Gland, https://etidiohnew.blogspot.com/2025/05/pregnant-dairy-heifers-express.html
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Pregnant Dairy #Heifers Express #Influenza A Virus #Receptors in the Mammary #Gland, https://etidiohnew.blogspot.com/2025/05/pregnant-dairy-heifers-express.html
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Pregnant Dairy #Heifers Express #Influenza A Virus #Receptors in the Mammary #Gland, https://etidiohnew.blogspot.com/2025/05/pregnant-dairy-heifers-express.html
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Mushroom A.stiptica Bitter Compounds and Human Taste Receptor Activation
https://pubs.acs.org/doi/10.1021/acs.jafc.4c12651
#HackerNews #Mushrooms #Taste #Receptors #Bitter #Compounds #Human #Biology #Research
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🫀 Sweet taste receptors in the heart: A new pathway for cardiac regulation
https://medicalxpress.com/news/2025-02-sweet-receptors-heart-pathway-cardiac.html
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''all five isolates harbored HA #markers (226Q and 228G), suggesting more efficient #binding to avian receptors than to human #receptors, while all five strains had amino acid #substitutions that included 133A and 156A which might increase binding affinity to human-like receptors''
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The two #systemin #peptide #receptors in tomatoes have opposite functions. While SYR1 activates systemin-induced #immune responses, SYR2 acts as an antagonist. Wounding preferentially induces the expression of SYR2 that attenuates immune responses by outcompeting SYR1 for binding with the co-receptor SERK3a
https://www.cell.com/action/showPdf?pii=S1534-5807%2824%2900670-1
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Pictures of AMPA receptors at synapses from Axel Brunger's lab. By averaging a lot of tomogram images, they could discern scaffolding molecules bound to the complexes.
These in situ images are lower resolution than purified protein, but retain the native organization and place the receptors somewhat at the side of vesicular docking sites.
https://www.biorxiv.org/content/10.1101/2024.10.19.619226v2
#synapses #neuroscience #CellularStructuralBiology #Receptors
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The #mammary #glands of #cows abundantly display #receptors for circulating #avian #H5 viruses
Source: Journal of Virology, ABSTRACTInfluenza A viruses (IAVs) from the H5N1 2.3.4.4b clade are circulating in dairy farms in the USA.; ruminants were presumed not to be hosts for IAVs. Previously, IAV-positive mammalian species were hunters and scavengers, possibly getting infected while feeding on infected birds. It is now recognized that H5N1 viruses that circulate in US…
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#Avian and #Human #Influenza A Virus #Receptors in #Bovine #Mammary #Gland, Emerg Infect Dis.: https://wwwnc.cdc.gov/eid/article/30/9/24-0696_article
An outbreak of influenza A (#H5N1) virus was detected in dairy cows in the #USA. We detected influenza A virus #sialic acid -α2,3/α2,6-galactose host receptors in bovine mammary glands by lectin histochemistry. Our results provide a rationale for the high levels of H5N1 virus in #milk from infected cows.
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#Avian and #Human #Influenza A Virus #Receptors in #Bovine #Mammary #Gland, Emerg Infect Dis.: https://wwwnc.cdc.gov/eid/article/30/9/24-0696_article
An outbreak of influenza A (#H5N1) virus was detected in dairy cows in the #USA. We detected influenza A virus #sialic acid -α2,3/α2,6-galactose host receptors in bovine mammary glands by lectin histochemistry. Our results provide a rationale for the high levels of H5N1 virus in #milk from infected cows.
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#Bovine #H5N1 #influenza virus binds poorly to #human-type #sialic acid #receptors, BioRxIV: https://www.biorxiv.org/content/10.1101/2024.08.01.606177v1
Using two different methods, we found that both of the 2.3.4.4b H5s bound efficiently to glycan receptors with terminally linked a2-3 sialic acid with no detectable binding to glycan receptors with terminally linked a2-6 sialic acid.
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#Cell #binding, uptake and #infection of #influenza A virus using recombinant #antibody-based #receptors. http://biorxiv.org/cgi/content/short/2024.07.29.605726v1?rss=1
#Human and #avian influenza A viruses bind to #sialic acid (Sia) receptors on cells as their primary receptors, and this results in endocytic uptake of the virus.
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The mammary #glands of #cows abundantly display #receptors for circulating avian #H5 viruses, BioRxIV, https://www.biorxiv.org/content/10.1101/2024.05.24.595667v2
Most of the #sialome of the cow and #goat respiratory tract is lined with #sialic acid modifications such as N-glycolyl and O-acetyl, such structures are not bound by IAV.
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The mammary #glands of #cows abundantly display #receptors for circulating avian #H5 viruses, BioRxIV, https://www.biorxiv.org/content/10.1101/2024.05.24.595667v2
Most of the #sialome of the cow and #goat respiratory tract is lined with #sialic acid modifications such as N-glycolyl and O-acetyl, such structures are not bound by IAV.
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The mammary #glands of #cows abundantly display #receptors for circulating avian #H5 viruses, BioRxIV, https://www.biorxiv.org/content/10.1101/2024.05.24.595667v2
Most of the #sialome of the cow and #goat respiratory tract is lined with #sialic acid modifications such as N-glycolyl and O-acetyl, such structures are not bound by IAV.
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The mammary #glands of #cows abundantly display #receptors for circulating avian #H5 viruses, BioRxIV, https://www.biorxiv.org/content/10.1101/2024.05.24.595667v2
Most of the #sialome of the cow and #goat respiratory tract is lined with #sialic acid modifications such as N-glycolyl and O-acetyl, such structures are not bound by IAV.
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The mammary #glands of #cows abundantly display #receptors for circulating avian #H5 viruses, BioRxIV, https://www.biorxiv.org/content/10.1101/2024.05.24.595667v2
Most of the #sialome of the cow and #goat respiratory tract is lined with #sialic acid modifications such as N-glycolyl and O-acetyl, such structures are not bound by IAV.
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The #avian and #human #influenza A virus #receptors #sialic acid (SA)-α2,3 and SA-α2,6 are widely expressed in the #bovine #mammary #gland, BioRxIV, https://www.biorxiv.org/content/10.1101/2024.05.03.592326v1?rss=1
IAVs isolated from chickens generally bind more tightly to SA-α2,3-Gal-β1,4 (chicken receptor), whereas IAVs isolated from duck to SA-α2,3-Gal-β1,3 (duck receptor). We found all receptors were expressed, to a different degree, in the mammary gland, respiratory tract, and cerebrum of beef and/or dairy cattle.
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#Translocons...what can we say? It's a process!
In a new #OpenAccess #JIPB paper, Yang et al. report on a converged ubiquitin-proteasome pathway for the degradation of TOC & TOM tail-anchored #receptors.
https://doi.org/10.1111/jipb.13645
@wileyplantsci
#PlantSci #chloroplast #mitochondrion #botany -
#Translocons...what can we say? It's a process!
In a new #OpenAccess #JIPB paper, Yang et al. report on a converged ubiquitin-proteasome pathway for the degradation of TOC & TOM tail-anchored #receptors.
https://doi.org/10.1111/jipb.13645
@wileyplantsci
#PlantSci #chloroplast #mitochondrion #botany -
#Avian #H6 #Influenza Viruses in #Vietnamese Live #Bird #Markets during 2018-2021 https://pubmed.ncbi.nlm.nih.gov/38543733/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=1LGAx__djGAJ9poBzWGqPtjEbBDtz4ipSRRPUplmgHEyyF_Ihj&fc=None&ff=20240328065908&v=2.18.0.post9+e462414
The Vietnamese H6 viruses analyzed here possess an #aminoacid motif in #HA that confers #binding to both avian- and human-type #receptors on host cells, consistent with their ability to infect #mammals.
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More weird stuff with Delta type #glutamate #receptors - GABA binding and a non-iontropic plasticity at inhibitory #synapses from the GluD1 subtype.
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Photoswitchable NMDA inhibition - from recombinant receptors to blocking tadpole locomotion. Nice work from Laetitia Mony and Pierre Paoletti.
#neuroscience #ionchannels #receptors
https://www.biorxiv.org/content/10.1101/2023.10.16.562518v2.abstract
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Always been curious how different interferons that signal through same receptor can have different functional effect. Here's a paper that shows how:
#interferon #immunology #receptor #receptors #Signalling https://www.science.org/doi/10.1126/scisignal.adf5494 -
A new perspective in #protein research focuses on #disordered areas.
https://phys.org/news/2023-07-perspective-protein-focuses-disordered-areas.html
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An international team of researchers, studying macaque #brains, have mapped out #neurotransmitter #receptors, revealing a potential role in distinguishing internal #thoughts and #emotions from those generated by external influences.
#Neuroscience #sflorg
https://www.sflorg.com/2023/06/ns0619230.html -
Molecular dynamics simulations of the dimer of AMPA-type glutamate receptor binding domains from DE Shaw and colleagues. Seems to confirm some of our earlier functional work on desensitization (including one of the first mutants we published in 2012!), and also the transient encounters of glutamate on its way to the binding site. 190 µs of simulations!
https://www.sciencedirect.com/science/article/pii/S0969212623000965#ionchannels #glutamate #MolecularDynamics #electrophysiology #receptors