#pzq — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #pzq, aggregated by home.social.
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Our paper on updated genetic mapping of #PZQ response in #schistosome is finally out in #AACJournal edited by the @ASMicrobiology. Get your #OpenAccess copy and have a nice weekend read!
Here's the link: https://journals.asm.org/doi/epub/10.1128/aac.01432-23
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Did you miss our latest paper on #praziquantel 💊 and #schistosome 🐛? We reanalyzed our data with the latest genome assembly. The main takeaway:
- #PZQ response is determined by only one QTL rather than 2 independent loci.
- The Sm.TRPM_PZQ gene is still differentially expressed.
- There are now only 3 gene isoforms and isoform 1 mainly explains the difference in expression.This demonstrates that high-quality genome assembly is critical for correct trait mapping.
📄: https://www.biorxiv.org/content/10.1101/2023.11.01.565202v1