#purine — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #purine, aggregated by home.social.
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I apologise for the lengthy read with this post but if you can spare a couple of minutes I hope you will find it beneficial if you have ever experienced these symptoms or know anyone who has had them. It might just save you some grief down the line 🙏
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I apologise for the lengthy read with this post but if you can spare a couple of minutes I hope you will find it beneficial if you have ever experienced these symptoms or know anyone who has had them. It might just save you some grief down the line 🙏
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Scientists uncover a multibillion-year epic written into the #chemistry_of_life.
#purine #biosynthesis #KEGG #evolution #ATP
https://phys.org/news/2024-05-scientists-uncover-multibillion-year-epic.html
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Scientists uncover a multibillion-year epic written into the #chemistry_of_life.
#purine #biosynthesis #KEGG #evolution #ATP
https://phys.org/news/2024-05-scientists-uncover-multibillion-year-epic.html
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"We find that #purine synthesis constitutes a bottleneck for metabolic expansion, which can be alleviated by non-autocatalytic phosphoryl coupling agents. Early phases of the expansion are enriched with #enzymes that are metal dependent and structurally symmetric, supporting models of early #biochemical #evolution. This expansion trajectory suggests distinct hypotheses regarding the tempo, mode and timing of metabolic pathway evolution"
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"We find that #purine synthesis constitutes a bottleneck for metabolic expansion, which can be alleviated by non-autocatalytic phosphoryl coupling agents. Early phases of the expansion are enriched with #enzymes that are metal dependent and structurally symmetric, supporting models of early #biochemical #evolution. This expansion trajectory suggests distinct hypotheses regarding the tempo, mode and timing of metabolic pathway evolution"
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Happy to share our just accepted #review on #multitarget approaches for the #synthesis of #purine and #pyrimidine derivatives. From the #prebiotic/#abiotic origin of life to new #green #chemistry strategies for #drugdiscovery.
https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/ejoc.202201288?utm_source=google&utm_medium=paidsearch&utm_campaign=R3MR425&utm_content=Chemistry -
Happy to share our just accepted #review on #multitarget approaches for the #synthesis of #purine and #pyrimidine derivatives. From the #prebiotic/#abiotic origin of life to new #green #chemistry strategies for #drugdiscovery.
https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/ejoc.202201288?utm_source=google&utm_medium=paidsearch&utm_campaign=R3MR425&utm_content=Chemistry