#proteinevolution — Public Fediverse posts

#Evolution is easier than we think, and one great way to see why is to look at what we know about #proteinevolution.

First stop: define "Protein Universe" and "Protein Space."

https://sfmatheson.blogspot.com/2024/07/protein-space-and-protein-universe.html

#Evolution is easier than we think, and one great way to see why is to look at what we know about #proteinevolution.

First stop: define "Protein Universe" and "Protein Space."

https://sfmatheson.blogspot.com/2024/07/protein-space-and-protein-universe.html

#Evolution is easier than we think, and one great way to see why is to look at what we know about #proteinevolution.

First stop: define "Protein Universe" and "Protein Space."

https://sfmatheson.blogspot.com/2024/07/protein-space-and-protein-universe.html

#Evolution is easier than we think, and one great way to see why is to look at what we know about #proteinevolution.

First stop: define "Protein Universe" and "Protein Space."

https://sfmatheson.blogspot.com/2024/07/protein-space-and-protein-universe.html

#Evolution is easier than we think, and one great way to see why is to look at what we know about #proteinevolution.

First stop: define "Protein Universe" and "Protein Space."

https://sfmatheson.blogspot.com/2024/07/protein-space-and-protein-universe.html

In this project, we screened de novo designed protein libraries without natural ancestry for function, using #microfluidic droplets - and massively enriched short, truncated protein fragments. Turns out that these ≈ 40- to 60-residue fragments oligomerize to form a dynamic, catalytically proficient assembly, just as primordial peptides might have formed early enzymes during the prebiotic events that led to the #OriginOfLife! #ProteinEvolution

In this project, we screened de novo designed protein libraries without natural ancestry for function, using #microfluidic droplets - and massively enriched short, truncated protein fragments. Turns out that these ≈ 40- to 60-residue fragments oligomerize to form a dynamic, catalytically proficient assembly, just as primordial peptides might have formed early enzymes during the prebiotic events that led to the #OriginOfLife! #ProteinEvolution

In this project, we screened de novo designed protein libraries without natural ancestry for function, using #microfluidic droplets - and massively enriched short, truncated protein fragments. Turns out that these ≈ 40- to 60-residue fragments oligomerize to form a dynamic, catalytically proficient assembly, just as primordial peptides might have formed early enzymes during the prebiotic events that led to the #OriginOfLife! #ProteinEvolution

In this project, we screened de novo designed protein libraries without natural ancestry for function, using #microfluidic droplets - and massively enriched short, truncated protein fragments. Turns out that these ≈ 40- to 60-residue fragments oligomerize to form a dynamic, catalytically proficient assembly, just as primordial peptides might have formed early enzymes during the prebiotic events that led to the #OriginOfLife! #ProteinEvolution

🎉 Excited to share that I've been awarded the NOMIS-ETH Postdoctoral Fellowship to do research on the origin of life! Starting this September, I'll join the Panke group at the Department of Biosystems Science and Engineering (D-BSSE) in Basel and the Centre for Origin and Prevalence of Life (COPL) of ETH Zürich. I'm very grateful to the NOMIS Foundation for this incredible opportunity! 🌱🔬 #OriginOfLife #ProteinEvolution

https://copl.ethz.ch/news/COPL-news-channel/2024/03/2024-cohort-of-the-nomis-eth-fellows.html

🎉 Excited to share that I've been awarded the NOMIS-ETH Postdoctoral Fellowship to do research on the origin of life! Starting this September, I'll join the Panke group at the Department of Biosystems Science and Engineering (D-BSSE) in Basel and the Centre for Origin and Prevalence of Life (COPL) of ETH Zürich. I'm very grateful to the NOMIS Foundation for this incredible opportunity! 🌱🔬 #OriginOfLife #ProteinEvolution

https://copl.ethz.ch/news/COPL-news-channel/2024/03/2024-cohort-of-the-nomis-eth-fellows.html

🎉 Excited to share that I've been awarded the NOMIS-ETH Postdoctoral Fellowship to do research on the origin of life! Starting this September, I'll join the Panke group at the Department of Biosystems Science and Engineering (D-BSSE) in Basel and the Centre for Origin and Prevalence of Life (COPL) of ETH Zürich. I'm very grateful to the NOMIS Foundation for this incredible opportunity! 🌱🔬 #OriginOfLife #ProteinEvolution

https://copl.ethz.ch/news/COPL-news-channel/2024/03/2024-cohort-of-the-nomis-eth-fellows.html

🎉 Excited to share that I've been awarded the NOMIS-ETH Postdoctoral Fellowship to do research on the origin of life! Starting this September, I'll join the Panke group at the Department of Biosystems Science and Engineering (D-BSSE) in Basel and the Centre for Origin and Prevalence of Life (COPL) of ETH Zürich. I'm very grateful to the NOMIS Foundation for this incredible opportunity! 🌱🔬 #OriginOfLife #ProteinEvolution

https://copl.ethz.ch/news/COPL-news-channel/2024/03/2024-cohort-of-the-nomis-eth-fellows.html

Following up on yesterday's post about the vast universe of protein sequence space. I mentioned Dan Dennett's brilliant Library of Mendel, itself a subset of the famous Library of Babel.

Today I go more deliberately through the Library of Babel concept, and rename the protein library to The Library of Maynard Smith. (Frances Arnold at Caltech already did that, more than 10 years ago!)

#EvolutionIsEasy
#ProteinEvolution
#blaugust2023
#scienceblogging
#AdaptiveWalk

https://sfmatheson.blogspot.com/2023/08/contemplating-libraries-in-biology-not.html

Following up on yesterday's post about the vast universe of protein sequence space. I mentioned Dan Dennett's brilliant Library of Mendel, itself a subset of the famous Library of Babel.

Today I go more deliberately through the Library of Babel concept, and rename the protein library to The Library of Maynard Smith. (Frances Arnold at Caltech already did that, more than 10 years ago!)

#EvolutionIsEasy
#ProteinEvolution
#blaugust2023
#scienceblogging
#AdaptiveWalk

https://sfmatheson.blogspot.com/2023/08/contemplating-libraries-in-biology-not.html

Following up on yesterday's post about the vast universe of protein sequence space. I mentioned Dan Dennett's brilliant Library of Mendel, itself a subset of the famous Library of Babel.

Today I go more deliberately through the Library of Babel concept, and rename the protein library to The Library of Maynard Smith. (Frances Arnold at Caltech already did that, more than 10 years ago!)

#EvolutionIsEasy
#ProteinEvolution
#blaugust2023
#scienceblogging
#AdaptiveWalk

https://sfmatheson.blogspot.com/2023/08/contemplating-libraries-in-biology-not.html

Following up on yesterday's post about the vast universe of protein sequence space. I mentioned Dan Dennett's brilliant Library of Mendel, itself a subset of the famous Library of Babel.

Today I go more deliberately through the Library of Babel concept, and rename the protein library to The Library of Maynard Smith. (Frances Arnold at Caltech already did that, more than 10 years ago!)

#EvolutionIsEasy
#ProteinEvolution
#blaugust2023
#scienceblogging
#AdaptiveWalk

https://sfmatheson.blogspot.com/2023/08/contemplating-libraries-in-biology-not.html

Following up on yesterday's post about the vast universe of protein sequence space. I mentioned Dan Dennett's brilliant Library of Mendel, itself a subset of the famous Library of Babel.

Today I go more deliberately through the Library of Babel concept, and rename the protein library to The Library of Maynard Smith. (Frances Arnold at Caltech already did that, more than 10 years ago!)

#EvolutionIsEasy
#ProteinEvolution
#blaugust2023
#scienceblogging
#AdaptiveWalk

https://sfmatheson.blogspot.com/2023/08/contemplating-libraries-in-biology-not.html

Yet evolution has found thousands of functional proteins, some marvels of design.

Evolution is easy.

2/2

#proteinevolution
#blaugust2023

https://sfmatheson.blogspot.com/2023/08/the-library-of-possible-proteins-is.html

Yet evolution has found thousands of functional proteins, some marvels of design.

Evolution is easy.

2/2

#proteinevolution
#blaugust2023

https://sfmatheson.blogspot.com/2023/08/the-library-of-possible-proteins-is.html

Yet evolution has found thousands of functional proteins, some marvels of design.

Evolution is easy.

2/2

#proteinevolution
#blaugust2023

https://sfmatheson.blogspot.com/2023/08/the-library-of-possible-proteins-is.html

Yet evolution has found thousands of functional proteins, some marvels of design.

Evolution is easy.

2/2

#proteinevolution
#blaugust2023

https://sfmatheson.blogspot.com/2023/08/the-library-of-possible-proteins-is.html

Yet evolution has found thousands of functional proteins, some marvels of design.

Evolution is easy.

2/2

#proteinevolution
#blaugust2023

https://sfmatheson.blogspot.com/2023/08/the-library-of-possible-proteins-is.html

According to the Boston Consulting Group increasing the global market share of alternative proteins from 2% to 8% by 2030 could yield an emissions reduction equivalent to decarbonising 95% of the aviation industry. #ClimateChange #proteinevolution #BCG

According to the Boston Consulting Group increasing the global market share of alternative proteins from 2% to 8% by 2030 could yield an emissions reduction equivalent to decarbonising 95% of the aviation industry. #ClimateChange #proteinevolution #BCG

According to the Boston Consulting Group increasing the global market share of alternative proteins from 2% to 8% by 2030 could yield an emissions reduction equivalent to decarbonising 95% of the aviation industry. #ClimateChange #proteinevolution #BCG

According to the Boston Consulting Group increasing the global market share of alternative proteins from 2% to 8% by 2030 could yield an emissions reduction equivalent to decarbonising 95% of the aviation industry. #ClimateChange #proteinevolution #BCG

#introduction

Hi, I'm a biochemist enthusiastic about #enzymes, #biocatalysis and #ProteinEngineering & #ProteinEvolution.

I did my PhD with Florian Hollfelder at the #UniversityofCambridge working on #DirectedEvolution of enzymes using droplet #microfluidics. Currently, I am doing a postdoc at #ETHZurich, studying which properties determine a protein’s innovability towards new function.

Looking forward to learning about cool preprints/papers and finding a lively scientific community here!

#introduction

Hi, I'm a biochemist enthusiastic about #enzymes, #biocatalysis and #ProteinEngineering & #ProteinEvolution.

I did my PhD with Florian Hollfelder at the #UniversityofCambridge working on #DirectedEvolution of enzymes using droplet #microfluidics. Currently, I am doing a postdoc at #ETHZurich, studying which properties determine a protein’s innovability towards new function.

Looking forward to learning about cool preprints/papers and finding a lively scientific community here!

#introduction

Hi, I'm a biochemist enthusiastic about #enzymes, #biocatalysis and #ProteinEngineering & #ProteinEvolution.

I did my PhD with Florian Hollfelder at the #UniversityofCambridge working on #DirectedEvolution of enzymes using droplet #microfluidics. Currently, I am doing a postdoc at #ETHZurich, studying which properties determine a protein’s innovability towards new function.

Looking forward to learning about cool preprints/papers and finding a lively scientific community here!

#introduction

Hi, I'm a biochemist enthusiastic about #enzymes, #biocatalysis and #ProteinEngineering & #ProteinEvolution.

I did my PhD with Florian Hollfelder at the #UniversityofCambridge working on #DirectedEvolution of enzymes using droplet #microfluidics. Currently, I am doing a postdoc at #ETHZurich, studying which properties determine a protein’s innovability towards new function.

Looking forward to learning about cool preprints/papers and finding a lively scientific community here!

#introduction

Hi, I'm a biochemist enthusiastic about #enzymes, #biocatalysis and #ProteinEngineering & #ProteinEvolution.

I did my PhD with Florian Hollfelder at the #UniversityofCambridge working on #DirectedEvolution of enzymes using droplet #microfluidics. Currently, I am doing a postdoc at #ETHZurich, studying which properties determine a protein’s innovability towards new function.

Looking forward to learning about cool preprints/papers and finding a lively scientific community here!

My "Hello World" post. Still figuring this place out, I think at first it will probably be a duplicate of my Twitter feed, let's see how things go. If you follow me you will see a lot of #compchem, #proteinevolution, #sciencepolicy, and random #toddlermom / #profmom posts.

My "Hello World" post. Still figuring this place out, I think at first it will probably be a duplicate of my Twitter feed, let's see how things go. If you follow me you will see a lot of #compchem, #proteinevolution, #sciencepolicy, and random #toddlermom / #profmom posts.

My "Hello World" post. Still figuring this place out, I think at first it will probably be a duplicate of my Twitter feed, let's see how things go. If you follow me you will see a lot of #compchem, #proteinevolution, #sciencepolicy, and random #toddlermom / #profmom posts.

My "Hello World" post. Still figuring this place out, I think at first it will probably be a duplicate of my Twitter feed, let's see how things go. If you follow me you will see a lot of #compchem, #proteinevolution, #sciencepolicy, and random #toddlermom / #profmom posts.