#proteinevolution — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #proteinevolution, aggregated by home.social.
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In this project, we screened de novo designed protein libraries without natural ancestry for function, using #microfluidic droplets - and massively enriched short, truncated protein fragments. Turns out that these ≈ 40- to 60-residue fragments oligomerize to form a dynamic, catalytically proficient assembly, just as primordial peptides might have formed early enzymes during the prebiotic events that led to the #OriginOfLife! #ProteinEvolution