#polysaccharide — Public Fediverse posts

.. We discuss our interpretation: that we may be seeing (unexpected) regions of high-MW HA that play a role in HA recognition and binding by HA-interacting proteins. At the same time, these (#NMR) methods should be important tools for studying the molecular and atomic features of the wide variety of #hyaluronicacid #polysaccharide based #biomaterials and hydrogels that are in use in the pharmaceutical industry and #biomedicalengineering.
Anyway, check out the paper: https://doi.org/10.1021/acsami.4c08428

A new preprint from the lab (together with Marthe Walvoort's group) is now on #bioRxiv : https://www.biorxiv.org/content/10.1101/2023.03.16.532902v1 This manuscript presents nice work by Pushpa Rampratap, who did a great job figuring out how to make 13C-enriched hyaluronic acid #polysaccharide for use in #ssNMR . More forthcoming on the applications, but this paper introduces the protocols for producing the high-molecular weight HA. Enjoy! #glycotime #nmrchat #TeamMassSpec (Feedback welcome!)