#pharmacometric — Public Fediverse posts

@ConorMahood @RolloTreadway I’m a pharmacometrician. I build mathematical models for how drugs are processed in the body and how they work to treat illness.

In #pharmacometric models, drugs moving through complex biological systems are often represented by interlinked “compartments” - see https://journals.sagepub.com/doi/pdf/10.1177/019262339502300203 for a massively more technical explanation!

TL;DR we use math to describe and predict how drugs work.

@ConorMahood @RolloTreadway I’m a pharmacometrician. I build mathematical models for how drugs are processed in the body and how they work to treat illness.

In #pharmacometric models, drugs moving through complex biological systems are often represented by interlinked “compartments” - see https://journals.sagepub.com/doi/pdf/10.1177/019262339502300203 for a massively more technical explanation!

TL;DR we use math to describe and predict how drugs work.

We can use #Pharmacometric models like these to #Simulate clinical trials, dose regimens and so on, in silico, so that we can predict what will happen when we actually give a drug to a human, and whether the design we have proposed for our clinical trial will actually work when we run it.

We can use #Pharmacometric models like these to #Simulate clinical trials, dose regimens and so on, in silico, so that we can predict what will happen when we actually give a drug to a human, and whether the design we have proposed for our clinical trial will actually work when we run it.