#peramivir — Public Fediverse posts on home.social

Giuseppe Michieli @[email protected] · 2024-08-23 · 09:03 UTC

[Articles] #Antivirals for #treatment of severe #influenza: a systematic #review and network meta-analysis of randomised controlled trials https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)01307-2/fulltext?rss=yes

In hospitalised patients with severe flu, #oseltamivir & #peramivir might reduce duration of hospitalisation compared with standard care or placebo, although certainty of evidence is low. Effects of all antivirals on mortality & other important patient outcomes are very uncertain due to scarce data from #RCTs.

#antivirals #treatment #influenza #review #oseltamivir #peramivir

Giuseppe Michieli @[email protected] · 2024-08-15 · 08:16 UTC

Whole- #Genome #Analysis of #Influenza #H1N1pdm09 Viruses Isolated from #ILI #Outpatients in #Myanmar & Community-Acquired #Oseltamivir - #Resistant Strains Present from 2015 to 2019 https://www.mdpi.com/1999-4915/16/8/1300

1 virus intra-subtype reassortment, collected in the '15 season. 3 viruses possessed #H275Y substitution in NA protein, appearing to be CA without prior administration of neuraminidase #inhibitors. These viruses exhibited highly reduced susceptibility to #oseltamivir & #peramivir.