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#pbpk — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #pbpk, aggregated by home.social.

  1. 🧩#ZeroPMPieces #12:
    How can you avoid #animaltesting when assessing the #toxicity of #PFAS and #PMT substances?

    Watch Sylvia Escher from
    @Fraunhofer ITEM
    explain #PBPK modelling and new approach methodologies (#NAMs)

    youtu.be/Zim_Y8Psrfc

    🧠🫀 🫁

  2. Physiologically-based PK () models, for example, find the middle ground between PK and , having a more mechanistic bent by taking into account anatomical, physiological, physical, and chemical descriptions of the phenomena involved in complex absorption, distribution, metabolic and elimination () processes, while remaining fundamentally driven by observed data.