#paxlovid — Public Fediverse posts

The good news is that a team member who came down with Covid the other day is feeling better. The bad news is that while she was able to get a paxlovid prescription right away, she decided to skip it because it cost $500.

#Paxlovid #Covid #UnitedStates #Healthcare

The good news is that a team member who came down with Covid the other day is feeling better. The bad news is that while she was able to get a paxlovid prescription right away, she decided to skip it because it cost $500.

#Paxlovid #Covid #UnitedStates #Healthcare

Old news but news! www.nature.com/articles/d41... #Ensiltrevir is a much better drug than #Paxlovid for #COVID in *every* single aspect: higher antiviral activity, longer half life, fewer drug - drug interactions and better clinical data (remember #Paxlovid failed their prophylaxis trials).

At last, a pill that can preve...

Old news - I saw this when I was in Japan back in March for a conference and my web and social feeds were full of Japanese news.
https://www.nature.com/articles/d41586-026-01546-0

#Ensiltrevir is a much better drug than #Paxlovid for #COVID in *every* single aspect: higher antiviral activity, longer half life, fewer drug - drug interactions and better clinical data (remember #Paxlovid failed their prophylaxis trials).

Old news - I saw this when I was in Japan back in March for a conference and my web and social feeds were full of Japanese news.
https://www.nature.com/articles/d41586-026-01546-0

#Ensiltrevir is a much better drug than #Paxlovid for #COVID in *every* single aspect: higher antiviral activity, longer half life, fewer drug - drug interactions and better clinical data (remember #Paxlovid failed their prophylaxis trials).

Next-generation #inhibitors of #SARS-CoV-2 #Mpro overcome the deficiencies of #Paxlovid, https://etidiohnew.blogspot.com/2026/04/next-generation-inhibitors-of-sars-cov.html

Next-generation #inhibitors of #SARS-CoV-2 #Mpro overcome the deficiencies of #Paxlovid, https://etidiohnew.blogspot.com/2026/04/next-generation-inhibitors-of-sars-cov.html

@W6KME

I hear you.

When I had get some for spouse and kid, months back, first pharmacy said.

"Oh, we don't have any. Oh, wait, maybe, maybe we do? Oh, here is a whole box of #paxlovid doses! Wait, oh, no nevermind, these are expired so we will throw them all away! Nope, sorry! Throwing them away!"

So I drove frantically to the next pharmacy, in the next city to finally find some..

#covid

@W6KME

Thank you for isolating to protect others.

Thank you for taking #paxlovid to reduce #Covid 's effects on you.

These things are important, and good to do!

@W6KME

Thank you for isolating to protect others.

Thank you for taking #paxlovid to reduce #Covid 's effects on you.

These things are important, and good to do!

Apotheker sollen Paxlovid illegal nach China verkauft haben

Lange war spekuliert worden, nun sieht die Staatsanwaltschaft Frankfurt den Verdacht nach Informationen von WDR, NDR und SZ in mehreren Fällen bestätigt: Apotheker sollen das Corona-Medikament Paxlovid illegal nach China verkauft haben.

➡️ https://www.tagesschau.de/investigativ/ndr-wdr/corona-medikament-paxlovid-apotheken-china-100.html?at_medium=mastodon&at_campaign=tagesschau.de

#Paxlovid #Apotheker #China

Apotheker sollen Paxlovid illegal nach China verkauft haben

Lange war spekuliert worden, nun sieht die Staatsanwaltschaft Frankfurt den Verdacht nach Informationen von WDR, NDR und SZ in mehreren Fällen bestätigt: Apotheker sollen das Corona-Medikament Paxlovid illegal nach China verkauft haben.

➡️ https://www.tagesschau.de/investigativ/ndr-wdr/corona-medikament-paxlovid-apotheken-china-100.html?at_medium=mastodon&at_campaign=tagesschau.de

#Paxlovid #Apotheker #China

@saramg I wish I could tell you the horrible taste gets better, but it doesn't. Stayed with me until about 24h after the last dose.

The taste was by far the worst part of #Paxlovid .

@saramg I wish I could tell you the horrible taste gets better, but it doesn't. Stayed with me until about 24h after the last dose.

The taste was by far the worst part of #Paxlovid .

Less than a week after shaking off #Covid19 with the help of #paxlovid, I finished a 10k race today, taking 13 minutes off my last time. Thank you, #scientists and #vaccines.

Btw, another family member (about same age) who caught covid at the same event as I did, and displayed symptoms starting about the same time, still feels like shit today. They were not up on vax, didn't test and did not ask for paxlovid.

Thank you for your attention to this matter.

Less than a week after shaking off #Covid19 with the help of #paxlovid, I finished a 10k race today, taking 13 minutes off my last time. Thank you, #scientists and #vaccines.

Btw, another family member (about same age) who caught covid at the same event as I did, and displayed symptoms starting about the same time, still feels like shit today. They were not up on vax, didn't test and did not ask for paxlovid.

Thank you for your attention to this matter.

Day 5 with #covid19:
Slept well last night, and feel completely fine today. No symptoms, just very hungry.
I still have today and tomorrow on #Paxlovid. I am surprised it improved so quickly.
Still social distancing. I took a 3 mile walk today and it felt great.

Day 5 with #covid19:
Slept well last night, and feel completely fine today. No symptoms, just very hungry.
I still have today and tomorrow on #Paxlovid. I am surprised it improved so quickly.
Still social distancing. I took a 3 mile walk today and it felt great.

Day 3 with #Covid19. Its been 3 years since my last infection. The first time around was severe, having lost taste and smell, and struggled to breathe, was ill nearly 2 weeks. I have kept up with vaccinations (except this season). Compared to last time, this is fairly mild, but still no fun.
Runny nose, aches, dry cough, sneezing, itchy eyes, no discernable temp.
Day 2 on #paxlovid, and I have the 'metallic' taste in my mouth they warned about. It is really icky, but if it can shorten this illness a bit, I'm in.
My spouse, who has never had covid, has rightly settled in at the lake place for the foreseeable future.

Day 3 with #Covid19. Its been 3 years since my last infection. The first time around was severe, having lost taste and smell, and struggled to breathe, was ill nearly 2 weeks. I have kept up with vaccinations (except this season). Compared to last time, this is fairly mild, but still no fun.
Runny nose, aches, dry cough, sneezing, itchy eyes, no discernable temp.
Day 2 on #paxlovid, and I have the 'metallic' taste in my mouth they warned about. It is really icky, but if it can shorten this illness a bit, I'm in.
My spouse, who has never had covid, has rightly settled in at the lake place for the foreseeable future.

Welp, I tested positive for #covid19 today. Now my holiday will be spent at home forming an opinion on #Paxlovid, rather than beer drinking at the lake, infecting family and friends.

Welp, I tested positive for #covid19 today. Now my holiday will be spent at home forming an opinion on #Paxlovid, rather than beer drinking at the lake, infecting family and friends.

Paxlovid and Kidney Transplant, the cyclosporine edition: journals.lww.com/kidney360/ab... Our local experience case series, now in the @asnpublications.bsky.social #Kidney360 #Covid #Paxlovid

Evaluation of a Protocol Manag...

Dear #America

Isn’t #socialisedmedicine “evil”?!

My #Paxlovid #Covid #meds #retail at Aus$1,115.31 a pack.

I actually pay Aus$6.90

#auspol #USPol #HealthCare

#CovidIsNotOver #SocializedMedicine

I decided to not fill the #paxlovid prescription. I'm fighting it with Tylenol Complete for the symptoms, #zinc, #vitaminC & #echinacea. I've been diligent with getting my #COVID19 #boosters which I believe has buffered the full impact it could do to my system. Resting up & staying hydrated.

If you can't taste the salt,
and aceto tastes bald,
that's the cove...
that's the cove...

Second time in my life I have a positive #COVID #COVID19 test.

And I _THOUGHT I SHOULD HAVE MASKED AND I DIDN'T_

Oh well. At least I have a prescription for #paxlovid this time, but I don't think I can get it filled before Monday...

If you can't taste the salt,
and aceto tastes bald,
that's the cove...
that's the cove...

Second time in my life I have a positive #COVID #COVID19 test.

And I _THOUGHT I SHOULD HAVE MASKED AND I DIDN'T_

Oh well. At least I have a prescription for #paxlovid this time, but I don't think I can get it filled before Monday...

Your govt at work:Paxlovid Medicare with Medigap Insurance: $263. With GoodRX: $1,500. Before the Covid crisis was declared over: Nil. Feels like they'd just assume we die.

Government efficiency, my ass.

#Covid #COVID19 #Paxlovid #Mask #Health #Medicare #Author #Writer #WritersOfMastodon #WritingCommunity

Your govt at work:Paxlovid Medicare with Medigap Insurance: $263. With GoodRX: $1,500. Before the Covid crisis was declared over: Nil. Feels like they'd just assume we die.

Government efficiency, my ass.

#Covid #COVID19 #Paxlovid #Mask #Health #Medicare #Author #Writer #WritersOfMastodon #WritingCommunity

· People with recent COVID-19 at higher risk for other viral and bacterial infections
· A 15-day course of #Paxlovid did not “significantly improve health outcomes in participants with #LongCOVID
· 2. study showed that Paxlovid taken within 5 days of infection with COVID-19 did help with the acute phase of COVID-19 in children
· Rapamycin, a drug used for organ transplants, may help alleviate symptoms of myalgic encephalomyelitis #MECFS

https://thesicktimes.org/2025/04/08/research-updates-april-8/

#ResearchUpdates #COVID19

· People with recent COVID-19 at higher risk for other viral and bacterial infections
· A 15-day course of #Paxlovid did not “significantly improve health outcomes in participants with #LongCOVID
· 2. study showed that Paxlovid taken within 5 days of infection with COVID-19 did help with the acute phase of COVID-19 in children
· Rapamycin, a drug used for organ transplants, may help alleviate symptoms of myalgic encephalomyelitis #MECFS

https://thesicktimes.org/2025/04/08/research-updates-april-8/

#ResearchUpdates #COVID19

#vipintukur on X wrote:

Researchers have developed an oral antiviral drug candidate for #COVID19 that could overcome major limitations of #Paxlovid, currently the most prescribed oral treatment.

🧵https://threadreaderapp.com/thread/1907829320304791834.html

#vipintukur on X wrote:

Researchers have developed an oral antiviral drug candidate for #COVID19 that could overcome major limitations of #Paxlovid, currently the most prescribed oral treatment.

🧵https://threadreaderapp.com/thread/1907829320304791834.html

"Covid Protocol" goes like this:

Sick person isolated in room, block door with towel, only come through rest of house with #N95 briefly. Tray table outside door for food drop off. Disinfect everything.

#paxlovid ASAP for sick, lower #covid damage.

Heater off, open windows, box fans in windows to make positive pressure in main house, negative pressure in sick room, dumping sick air out bedroom window.

Constant air flow.

Yes, we fucking freeze.

All-clear when RAT clear, and nobody sick.

"There are over 200 different symptoms that can appear in any different combination. And then the other piece about it is there are about six different mechanisms of what can be causing long COVID. So everyone has in common COVID as the thing that started their long COVID.

However, there are so many different physiological things going wrong in different people with long COVID, they might require different treatments."

"There are actually a lot of great trials going on [...] one looking at mitochondrial dysfunction is Rapamycin, which David Petrino’s group is running."

"There’s a few looking at immunomodulation with JAK inhibitors, both the Baricitinib trial by Wes Eli’s group and another JAK inhibitor trial that’s starting at Harvard. Another immunomodulation option is IVIG, which is being run by the NIH RECOVER consortium. This one’s tricky because it’s not super scalable. You have to get the antibodies from people and then infuse them into other people"

"And then the other mechanism that’s being looked at a lot now is viral persistence, both through a few different monoclonal antibodies trials– Michael Peluso’s, funded by the Patient Led Research Collaborative. Nancy Klimas is just starting one funded by the Schmidt Initiative for Long COVID and the state of California. And then there’s another one in Italy that’s funded by industry, all looking at monoclonal antibodies. And then the last viral persistence one is also being run by the Petrino group on Truvada, which is an HIV antiviral."

https://www.sciencefriday.com/segments/paxlovid-long-covid/

@patientled

#SARSCoV2 #LongCovid #paxlovid #LC #PwLC #PASC #COVID #COVID19

"There are over 200 different symptoms that can appear in any different combination. And then the other piece about it is there are about six different mechanisms of what can be causing long COVID. So everyone has in common COVID as the thing that started their long COVID.

However, there are so many different physiological things going wrong in different people with long COVID, they might require different treatments."

"There are actually a lot of great trials going on [...] one looking at mitochondrial dysfunction is Rapamycin, which David Petrino’s group is running."

"There’s a few looking at immunomodulation with JAK inhibitors, both the Baricitinib trial by Wes Eli’s group and another JAK inhibitor trial that’s starting at Harvard. Another immunomodulation option is IVIG, which is being run by the NIH RECOVER consortium. This one’s tricky because it’s not super scalable. You have to get the antibodies from people and then infuse them into other people"

"And then the other mechanism that’s being looked at a lot now is viral persistence, both through a few different monoclonal antibodies trials– Michael Peluso’s, funded by the Patient Led Research Collaborative. Nancy Klimas is just starting one funded by the Schmidt Initiative for Long COVID and the state of California. And then there’s another one in Italy that’s funded by industry, all looking at monoclonal antibodies. And then the last viral persistence one is also being run by the Petrino group on Truvada, which is an HIV antiviral."

https://www.sciencefriday.com/segments/paxlovid-long-covid/

@patientled

#SARSCoV2 #LongCovid #paxlovid #LC #PwLC #PASC #COVID #COVID19

👀🧵by Dr. Vipin M. Vashishtha (@vipintukur on Twitter): "Why SARS-CoV-2 bounces back after #Paxlovid treatment A NEW study found that the antiviral treatment, especially when given early in the course of the infection, can leave behind target cells..." threadreaderapp.com/thread/18869...

After 5 years of fighting to not get #COVID, wearing masks, not eating indoors, etc. I finally tested positive after my dad’s funeral.

I’ve had every vaccine and booster and so far the symptoms are very mild. 72 hours after exposure:
- Chills; but no fever.
- Body aches
- Slight soar throat
- Little appetite

Not a candidate for #Paxlovid even with #UC since I’m not on an immunotherapy.

I’m hoping it passes quickly.

#WearAMask #GetBoosted #VaccinesWork #COVIDIsntOver #COVID19

After 5 years of fighting to not get #COVID, wearing masks, not eating indoors, etc. I finally tested positive after my dad’s funeral.

I’ve had every vaccine and booster and so far the symptoms are very mild. 72 hours after exposure:
- Chills; but no fever.
- Body aches
- Slight soar throat
- Little appetite

Not a candidate for #Paxlovid even with #UC since I’m not on an immunotherapy.

I’m hoping it passes quickly.

#WearAMask #GetBoosted #VaccinesWork #COVIDIsntOver #COVID19

Jut, jut... Rebound-Effekt nach #Paxlovid.*
Was wissen wir darüber? 😬
(Mein Stand bisher: Es soll mild(er) sein. Symptome bekämpfen, nicht erneut Paxlovid. Richtig? Falsch? Bitte Quellen.)

#TeamVorsicht #Risikogruppe

*War klar, dass ich das auch wieder abgreife, wa?

Jut, jut... Rebound-Effekt nach #Paxlovid.*
Was wissen wir darüber? 😬
(Mein Stand bisher: Es soll mild(er) sein. Symptome bekämpfen, nicht erneut Paxlovid. Richtig? Falsch? Bitte Quellen.)

#TeamVorsicht #Risikogruppe

*War klar, dass ich das auch wieder abgreife, wa?

Omg.

An elderly family member is in the ER for a fall. This person is 83, has Parkinson's Disease, and is a lifelong smoker. While in the ER, they tested positive for covid.

Their caregiver requested #Paxlovid and reports, "The doctor that was here was like we don't prescribe that and it doesn't work. That is exactly what she said."

🤯 ?!?!

1/2

#CovidIsNotOver

Final (hopefully!) #covid update.

I have a lingering cough and stuffy nose to remind me of my recent – and only 2nd – bout of Covid. My first 2 1/2 days of fever were pretty bad. I didn’t get Paxlovid because of knowing of several people who took it and then relapsed. Just my own personal decision and experience. Fortunately, it never went into my lungs; if it had, I definitely would have gone the #paxlovid route.

I’m so glad I got my booster shot in November! Could’ve been much worse…

#mask

Effect of #paxlovid on adverse outcomes from #COVID19 in kidney disease. Acknowledging the limitations of a propensity-score matched study, use was associated with ⬇️ hospitalizations, deaths, & CV events.
🙏 @DavidJoffe64 at X

https://academic.oup.com/ofid/article/doi/10.1093/ofid/ofae756/7935346