#pathogenesis — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #pathogenesis, aggregated by home.social.
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The #Environmental Polycyclic Aromatic Hydrocarbon (PAH) #Benzopyrene (BP) Alters #SARS-CoV-2 #Pathogenesis in a Mouse #Model of Disease, https://etidiohnew.blogspot.com/2026/07/the-environmental-polycyclic-aromatic.html
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The #Environmental Polycyclic Aromatic Hydrocarbon (PAH) #Benzopyrene (BP) Alters #SARS-CoV-2 #Pathogenesis in a Mouse #Model of Disease, https://etidiohnew.blogspot.com/2026/07/the-environmental-polycyclic-aromatic.html
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Neither #Ebola without #Pathogenesis nor #Pathogenesis without #Ebola.
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Emerging and re-emerging vector-borne and other #zoonotic #RNA #viruses: #pathogenesis, #climate-driven dynamics, and strategies for global control, https://etidiohnew.blogspot.com/2026/05/emerging-and-re-emerging-vector-borne.html
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Emerging and re-emerging vector-borne and other #zoonotic #RNA #viruses: #pathogenesis, #climate-driven dynamics, and strategies for global control, https://etidiohnew.blogspot.com/2026/05/emerging-and-re-emerging-vector-borne.html
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Loss of nsp14-exonuclease activity impairs the #replication, proofreading, fitness, and #pathogenesis of #SARS-CoV-2, https://etidiohnew.blogspot.com/2026/05/loss-of-nsp14-exonuclease-activity.html
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Loss of nsp14-exonuclease activity impairs the #replication, proofreading, fitness, and #pathogenesis of #SARS-CoV-2, https://etidiohnew.blogspot.com/2026/05/loss-of-nsp14-exonuclease-activity.html
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Respiratory #infections due to #human common cold #coronaviruses, #SARS-CoV, #MERS-CoV, and SARS-CoV-2: #epidemiology, #pathogenesis, clinical features, diagnostics, therapeutics, and vaccine landscapes, https://etidiohnew.blogspot.com/2026/05/respiratory-infections-due-to-human.html
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Respiratory #infections due to #human common cold #coronaviruses, #SARS-CoV, #MERS-CoV, and SARS-CoV-2: #epidemiology, #pathogenesis, clinical features, diagnostics, therapeutics, and vaccine landscapes, https://etidiohnew.blogspot.com/2026/05/respiratory-infections-due-to-human.html
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#Pathogenesis of #H5N1 Clade 2.3.4.4b in dry Jersey #cows following intramammary inoculation shows within-host compartmentalization, https://etidiohnew.blogspot.com/2026/03/pathogenesis-of-h5n1-clade-2344b-in-dry.html
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#Pathogenesis of #H5N1 Clade 2.3.4.4b in dry Jersey #cows following intramammary inoculation shows within-host compartmentalization, https://etidiohnew.blogspot.com/2026/03/pathogenesis-of-h5n1-clade-2344b-in-dry.html
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#Pathogenesis and #Research #Models of Acute #Influenza-Associated #Encephalitis / #Encephalopathy: An Update, https://etidiohnew.blogspot.com/2026/01/pathogenesis-and-research-models-of.html
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#Pathogenesis and #Research #Models of Acute #Influenza-Associated #Encephalitis / #Encephalopathy: An Update, https://etidiohnew.blogspot.com/2026/01/pathogenesis-and-research-models-of.html
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#Pathogenesis and Transmissibility of #MERS #Coronaviruses of African Origin in #Alpacas, https://etidiohnew.blogspot.com/2025/11/pathogenesis-and-transmissibility-of.html
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#Pathogenesis and Transmissibility of #MERS #Coronaviruses of African Origin in #Alpacas, https://etidiohnew.blogspot.com/2025/11/pathogenesis-and-transmissibility-of.html
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Resurgence of #human #metapneumovirus in the post #COVID19 era: #pathogenesis, epidemiological shifts, clinical #impact, and future #challenges, https://etidiohnew.blogspot.com/2025/06/resurgence-of-human-metapneumovirus-in.html
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Resurgence of #human #metapneumovirus in the post #COVID19 era: #pathogenesis, epidemiological shifts, clinical #impact, and future #challenges, https://etidiohnew.blogspot.com/2025/06/resurgence-of-human-metapneumovirus-in.html
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#Pathogenesis Induced by #Influenza Virus #Infection: Role of the Early Events of the Infection and the Innate Immune Response, https://etidiohnew.blogspot.com/2025/05/pathogenesis-induced-by-influenza-virus.html
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#Pathogenesis Induced by #Influenza Virus #Infection: Role of the Early Events of the Infection and the Innate Immune Response, https://etidiohnew.blogspot.com/2025/05/pathogenesis-induced-by-influenza-virus.html
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Subacute Sclerosing #Panencephalitis: Recent #Advances in #Pathogenesis, #Diagnosis, and #Treatment https://pubmed.ncbi.nlm.nih.gov/40235044/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=10CQYG4wH40EtHVSNOD9mofMx7F21fnuzqLzNKyqhr7y2YTgCd&fc=None&ff=20250416065008&v=2.18.0.post9+e462414
SSPE is invariably #fatal. Notably, reports of prolonged survival and disease stabilization have been documented, particularly with early and combined therapy.
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Subacute Sclerosing #Panencephalitis: Recent #Advances in #Pathogenesis, #Diagnosis, and #Treatment https://pubmed.ncbi.nlm.nih.gov/40235044/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=10CQYG4wH40EtHVSNOD9mofMx7F21fnuzqLzNKyqhr7y2YTgCd&fc=None&ff=20250416065008&v=2.18.0.post9+e462414
SSPE is invariably #fatal. Notably, reports of prolonged survival and disease stabilization have been documented, particularly with early and combined therapy.
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Effect of Prior #Influenza #H1N1pdm09 Virus #Infection on #Pathogenesis and #Transmission of #Human Influenza A(#H5N1) Clade 2.3.4.4b Virus in #Ferret Model, https://etidiohnew.blogspot.com/2025/02/effect-of-prior-influenza-h1n1pdm09.html
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Effect of Prior #Influenza #H1N1pdm09 Virus #Infection on #Pathogenesis and #Transmission of #Human Influenza A(#H5N1) Clade 2.3.4.4b Virus in #Ferret Model, https://etidiohnew.blogspot.com/2025/02/effect-of-prior-influenza-h1n1pdm09.html
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Enhanced #RNA #replication and #pathogenesis in recent #SARS-CoV-2 #variants harboring the L260F mutation in NSP6, https://etidiohnew.blogspot.com/2024/12/enhanced-rna-replication-and.html
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Enhanced #RNA #replication and #pathogenesis in recent #SARS-CoV-2 #variants harboring the L260F mutation in NSP6, https://etidiohnew.blogspot.com/2024/12/enhanced-rna-replication-and.html
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Viral #sepsis: #diagnosis, clinical #features, #pathogenesis, and #clinical considerations, https://etidiohnew.blogspot.com/2024/12/viral-sepsis-diagnosis-clinical.html
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Viral #sepsis: #diagnosis, clinical #features, #pathogenesis, and #clinical considerations, https://etidiohnew.blogspot.com/2024/12/viral-sepsis-diagnosis-clinical.html
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#Age-Dependent #Pathogenesis of #Influenza A Virus #H7N9 Mediated Through #PB1-F2-Induced Mitochondrial DNA Release and Activation of cGAS-STING-NF-κB Signaling
Source: Journal of Medical Virology, ABSTRACTExactly why human infection of avian influenza A virus H7N9 causes more severe disease in the elderly remains elusive. In this study, we found that H7N9 PB1-F2 is a pathogenic factor in 15–18-month-old BALB/C mice (aged mice) but not in 6–8-week-old young adult mice…
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#Age-Dependent #Pathogenesis of #Influenza A Virus #H7N9 Mediated Through #PB1-F2-Induced Mitochondrial DNA Release and Activation of cGAS-STING-NF-κB Signaling
Source: Journal of Medical Virology, ABSTRACTExactly why human infection of avian influenza A virus H7N9 causes more severe disease in the elderly remains elusive. In this study, we found that H7N9 PB1-F2 is a pathogenic factor in 15–18-month-old BALB/C mice (aged mice) but not in 6–8-week-old young adult mice…
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A systematic #review of #laboratory #investigations into the #pathogenesis of avian #influenza viruses in wild #avifauna of North #America
Source: Proceedings of the Royal Society Biological Sciences, AbstractThe lack of consolidated information regarding the response of wild bird species to infection with avian influenza virus (AIV) is a challenge to both conservation managers and researchers alike, with related sectors also impacted, such as public health and…
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A systematic #review of #laboratory #investigations into the #pathogenesis of avian #influenza viruses in wild #avifauna of North #America
Source: Proceedings of the Royal Society Biological Sciences, AbstractThe lack of consolidated information regarding the response of wild bird species to infection with avian influenza virus (AIV) is a challenge to both conservation managers and researchers alike, with related sectors also impacted, such as public health and…
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A systematic #[review of #laboratory #investigations into the #pathogenesis of avian #influenza viruses in wild #avifauna of North #America, BioRxIV: https://www.biorxiv.org/content/10.1101/2024.05.06.592734v3
This study represents the first comprehensive effort to compile available literature regarding the pathobiology of AIV's in all wild birds in over a decade. This database provides an opportunity to critically examine and assess what is known and identify where further insight is needed.
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A systematic #[review of #laboratory #investigations into the #pathogenesis of avian #influenza viruses in wild #avifauna of North #America, BioRxIV: https://www.biorxiv.org/content/10.1101/2024.05.06.592734v3
This study represents the first comprehensive effort to compile available literature regarding the pathobiology of AIV's in all wild birds in over a decade. This database provides an opportunity to critically examine and assess what is known and identify where further insight is needed.
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What The #Pox? #Review of #Poxviruses Affecting #Humans, J Clin Virol.: https://www.sciencedirect.com/science/article/abs/pii/S1386653224000817?dgcid=rss_sd_all
This review examines various poxviruses affecting humans, with discussion of less commonly encountered Poxviridae members, including #pathogenesis, #epidemiology, and #diagnostic methods. Poxvirus #treatment is beyond the intended scope of this review and will not be discussed.
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What The #Pox? #Review of #Poxviruses Affecting #Humans, J Clin Virol.: https://www.sciencedirect.com/science/article/abs/pii/S1386653224000817?dgcid=rss_sd_all
This review examines various poxviruses affecting humans, with discussion of less commonly encountered Poxviridae members, including #pathogenesis, #epidemiology, and #diagnostic methods. Poxvirus #treatment is beyond the intended scope of this review and will not be discussed.
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@Infoseepage Here another proof of what you're saying: #Pathogenesis of #H5N1 #Influenza Virus Infections in #Mice & #Ferret Models Differs According to #Respiratory Tract or #Digestive System Exposure, J Infect Dis.: https://academic.oup.com/jid/article/199/5/717/902376?login=false
Our results demonstrated that exposure of digestive system to H5N1 influenza viruses could initiate infection either through the #tonsil, with spread to respiratory tissues, or through #intestinal infection, with spread to the liver and #pancreas.
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@Infoseepage Here another proof of what you're saying: #Pathogenesis of #H5N1 #Influenza Virus Infections in #Mice & #Ferret Models Differs According to #Respiratory Tract or #Digestive System Exposure, J Infect Dis.: https://academic.oup.com/jid/article/199/5/717/902376?login=false
Our results demonstrated that exposure of digestive system to H5N1 influenza viruses could initiate infection either through the #tonsil, with spread to respiratory tissues, or through #intestinal infection, with spread to the liver and #pancreas.
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An ex vivo #human precision-cut #lung slice #platform provides insight into #SARS-CoV-2 #pathogenesis and #antiviral drug #efficacy, J Virol.: https://journals.asm.org/doi/full/10.1128/jvi.00794-24?af=R
We identified early induction of specific #cytokines, especially IP-10 and IL-8, as potential predictors for severe #COVID19, & uncovered a hitherto unrecognized phenomenon that while infectious virus disappears at late times of infection, viral #RNA persists and lung histopathology commences.
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An ex vivo #human precision-cut #lung slice #platform provides insight into #SARS-CoV-2 #pathogenesis and #antiviral drug #efficacy, J Virol.: https://journals.asm.org/doi/full/10.1128/jvi.00794-24?af=R
We identified early induction of specific #cytokines, especially IP-10 and IL-8, as potential predictors for severe #COVID19, & uncovered a hitherto unrecognized phenomenon that while infectious virus disappears at late times of infection, viral #RNA persists and lung histopathology commences.
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A systematic #review of #laboratory #investigations into the #pathogenesis of avian #influenza viruses in wild #avifauna of North #America, BioRxIV, https://www.biorxiv.org/content/10.1101/2024.05.06.592734v2
This study represents the first comprehensive effort to compile available literature regarding the pathobiology of AIVs in all wild birds in over a decade.
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A systematic #review of #laboratory #investigations into the #pathogenesis of avian #influenza viruses in wild #avifauna of North #America, BioRxIV, https://www.biorxiv.org/content/10.1101/2024.05.06.592734v2
This study represents the first comprehensive effort to compile available literature regarding the pathobiology of AIVs in all wild birds in over a decade.
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Divergent #Pathogenesis and #Transmission of Highly Pathogenic Avian #Influenza A(#H5N1) in #Swine, Emerg Infect Dis.: https://wwwnc.cdc.gov/eid/article/30/4/23-1141_article
-- We assessed susceptibility of swine to avian and mammalian HPAI H5N1 clade 2.3.4.4b strains using a pathogenesis and transmission model. All strains replicated in the lung of pigs and caused lesions consistent with influenza A infection. However, viral replication in the nasal cavity and transmission was only observed with mammalian isolates.
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Divergent #Pathogenesis and #Transmission of Highly Pathogenic Avian #Influenza A(#H5N1) in #Swine, Emerg Infect Dis.: https://wwwnc.cdc.gov/eid/article/30/4/23-1141_article
-- We assessed susceptibility of swine to avian and mammalian HPAI H5N1 clade 2.3.4.4b strains using a pathogenesis and transmission model. All strains replicated in the lung of pigs and caused lesions consistent with influenza A infection. However, viral replication in the nasal cavity and transmission was only observed with mammalian isolates.
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Contrasting roles of #MERS-CoV and #SARS-CoV-2 internal #proteins in #pathogenesis in mice, mBio: https://doi.org/10.1128/mbio.02476-23 #research #betacoronavirus #sarbecovirus #merbecovirus
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Contrasting roles of #MERS-CoV and #SARS-CoV-2 internal #proteins in #pathogenesis in mice, mBio: https://doi.org/10.1128/mbio.02476-23 #research #betacoronavirus #sarbecovirus #merbecovirus
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Highly pathogenic avian #influenza (#H5N1) #infection in #crows through #ingestion of infected crow #carcasses {in experimental setting}, Microb Pathog.: https://doi.org/10.1016/j.micpath.2023.106330 #research #pathology #pathogenesis #cannibalism
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Highly pathogenic avian #influenza (#H5N1) #infection in #crows through #ingestion of infected crow #carcasses {in experimental setting}, Microb Pathog.: https://doi.org/10.1016/j.micpath.2023.106330 #research #pathology #pathogenesis #cannibalism
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#Pathogenesis and #transmission #assessment of three swine-origin #influenza A(#H3N2) viruses with #zoonotic #risk to humans isolated in the #US from 2017-2020, J Infect Dis., https://doi.org/10.1093/infdis/jiad359 #pigs #zoonoses #enzootic #pandemic
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#Pathogenesis and #transmission #assessment of three swine-origin #influenza A(#H3N2) viruses with #zoonotic #risk to humans isolated in the #US from 2017-2020, J Infect Dis., https://doi.org/10.1093/infdis/jiad359 #pigs #zoonoses #enzootic #pandemic
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M. #tuberculosis (Mtb) resists killing by repressing the #autophagolysosome machinery. @imgsb show that NCoR1 regulates these processes in myeloid cells by fine-tuning ATP homeostasis via AMPK-mTOR-TFEB axis, so controlling Mtb #pathogenesis #PLOSBiology https://plos.io/3quNEGD
