#osteocyte — Public Fediverse posts

An osteocyte is the most abundant cell in mature bone. Here’s one in a 3D biomimetic hydrogel system.

Photograph: Shiva Muthuswamy/AIBN

#nanophotography
#osteocyte

“Bone mineral organization at the mesoscale: A review of mineral ellipsoids in bone and at bone interfaces”

🧪🔬🦴🩻

https://doi.org/10.1016/j.actbio.2022.02.024

#bone #biomaterials #science #microscopy #electronmicroscopy #bioimaging #imaging #osteocyte #collagen #apatite #science #engineering #biology #physics

🦴🩻🔬🧪 The complex hierarchical structure of bone, where smaller building blocks form progressively larger structures.

Full description in ALT text.

https://doi.org/10.1016/j.actbio.2018.11.018

#bone #osteocyte #biomaterials #osteology #biology #materialsscience #structuralbiology #orthopaedics #microscopy #bioimaging #health #healthcare #science

Cell-to-cell #mitochondrial transfer within the #osteocyte dendritic network regulates #bone tissue homeostasis, but how? This study shows that osteocytes release ADP under stress conditions, triggering mitochondrial transfer #PLOSBiology https://plos.io/3MdO2Ao

🧪🔬🦴💠 50 years of scanning electron microscopy of bone—a comprehensive overview of the important discoveries made and insights gained into bone material properties in health, disease, and taphonomy

https://www.nature.com/articles/s41413-019-0053-z

#bone #biomineralization #biology #osteocyte #collagen #apatite #mineral #science #electronmicroscopy #microscopy #imaging #biomaterials

🧪🔬🦴💠 Transformation of bone mineral morphology: From discrete marquise-shaped motifs to a continuous interwoven mesh

https://doi.org/10.1016/j.bonr.2020.100283

#bone #biomineralization #biology #osteocyte #collagen #apatite #mineral #science #electronmicroscopy #Ramanspectroscopy #imaging

🦴🩻🔬🧪 50 years of scanning electron #microscopy of #bone—a comprehensive overview of the important discoveries made and insights gained into bone material properties in #health, #disease, and #taphonomy

https://www.nature.com/articles/s41413-019-0053-z

#imaging #microscopy #biomaterials #osteocyte #biomineralization #science #biology #osteology #materialsscience #materials

2/3; #Introduction 🕰️ - My scholarly interests [‼️] include #bone repair #biomaterials, the #osteocyte (a remarkable cell in bone), #osseointegration of implants, #biomineralization. I think #bacteria are fascinating! #electronmicroscopy and #Ramanspectroscopy ftw! #academia #academicchatter #AcademicMastodon #Science #research #phd #mosstodon #icetodon #Fediverse #nature

🦴🔬 Between a rock and a hard place: Organisation of mineralised #collagen fibrils between the surface of a titanium implant and the nearest #osteocyte in human alveolar #bone.

#osseointegration #electronmicroscopy #implantology #osteology #biomineralization #biomaterials

🦴🔬#Osteocyte – the master orchestrator of #bone #remodeling. ~42 billion in the average adult human skeleton, #osteocytes make up ~90–95% of all #cells within bone, interconnected by ~3.7 trillion dendritic projections with an estimated, total end-to-end length of 175,000 km🔍

Alien invasion!!! 👾 👽 Under in vitro culture, a #human #mesenchymal #stemcell crawls into an #osteocyte lacuna (http://bit.ly/Osteocyte) at the #bone surface, observed by scanning #electron #microscopy 🔬 🦴 Forget shape-memory #alloys! #Cells remember! (Arrowheads = bone #mineral)

#biology #electronmicroscopy #stemcells #imaging #bioimaging #biomimicry #biomineralization #invitro #apatite

Imaging #bone with scanning electron microscopy? 🔬

Correlate – know better! 🦴👀

The combination of backscattered electron (BSE) and secondary electron (SE) imaging modes reveals a more accurate view of bone around #osteocyte lacunae, the small spaces where bone cells reside. 🔍💀 This information is crucial for understanding bone remodelling and how bone responds to injury or disease. 🤔📈

Read more:
https://nature.com/articles/s41413-019-0053-z

#biomaterials #electronmicroscopy #science #biology #physics #bioimaging

#Magnesium #whitlockite formation in the alveolar #bone, with #bisphosphonate exposure and osteolytic #skeletal #metastasis. Scanning electron microscopy, Micro-Raman spectroscopy, and energy dispersive X-ray spectroscopy reveal Mg-rich, rhomboidal nodules (200 nm to 2.4 µm) within the lacuno-canalicular space. Mg-whitlockite formation in #osteocyte lacunae is multifactorial in #nature and suggests altered bone #biomineralization.

Read more:
https://doi.org/10.1016/j.micron.2023.103441

#biology #pathology #science

Through the eyes of an #osteocyte. In #bone, this is what the environment of partially embedded osteocytes (osteoblastic–osteocytes) is like!

Scanning electron microscopy has been used to observe the orientation of mineral platelets in relation to osteoblastic–osteocyte lacunae on the surface of deproteinized trabecular bone in adult sheep.

Read more:
https://doi.org/10.1007/s00223-015-0072-8

@zeiss_micro #microscopy #biology #imaging #biomineralization #extracellularmatrix #friday

Here's a transmission electron microscopy (TEM) image of #bone showing mineralized #collagen and an #osteocyte lacuna containing microcalcifications of #apatite and #whitlockite.

Such #calcification or #mineral formation is part of normal physiological processes such as #apoptosis but can also indicate #pathology.

The specimen was prepared using focussed ion beam scanning electron microscopy (FIB-SEM).

Read more:
https://pubs.acs.org/doi/abs/10.1021/acs.nanolett.7b02888

#ThinSectionThursday #Biomaterials #ElectronMicroscopy