#onctwitter — Public Fediverse posts

Set a ⏲ to join #TumorBoardTuesday on 02.21.23 at 8pm ET

👩🏻‍⚕️@NarjustFlorezMD @ShrutiPatelMD👩🏽‍⚕️
📰Options for IO combos for treatement of #NSCLC

🫁While we finalize the case, collect FREE #CME (AMA & MOC)

👉🏽http://integrityce.com/tbt 👈🏼#OncTwitter #LungCancer #LCSM

3/#TumorBoardTuesday #gyncsm #OncTwitter

🤔Missed the #EndometrialCancer #MedTweetorial earlier this wk?
🤯Feeling left behind?

Don't fret, it's here📍

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RT @BonumCe
1/ #OncTwitter #TumorBoardTuesday
✅#EndometrialCancer #MedTweetorial🧵
w @DrMMurphy @MeganLeigh127 @TumorBoardTues

🧬Tx response
🧪Trial results
🔬Tox for TKI-ICI

🆓#CME 🔗 http://bit.ly/3VBGJEJ
Supported by educational grants from Eisai & @Merck
https://twitter.com/BonumCe/status/1615519240542646275

3/#TumorBoardTuesday #BonumCE #OncTwitter #GynCSM #gynonc #EndometrialCancer

🟠Earn 🆓 #CME 🏆
🟠#CME ℹ️🔗http://bit.ly/3YRDkog

📸 Faculty disclosures & important CME info 👇

💥#EndometrialCancer TKI/IO safety data & AE mgmt webinar 💥┈┈┈ w @DrMMurphy & @drteplinsky ┈┈┈🔹#CME info 👉 http://bit.ly/3Vqtabi 👈 @BonumCe ┈┈┈🔸Supported by edu grants from Eisai & @Merck 🔹#TumorBoardTuesday #gyncsm #OncTwitter https://twitter.com/i/broadcasts/1yoJMZrrqbNxQ

5...4...3...2...1...it's the final countdown
⏰30m warning
🔥#EndometrialCancer #webinar w @DrMMurphy & @drteplinsky🔥

👩‍🏫B4 we begin...👩🏻‍🏫
✅Answer #PreTest polls 👇
🔁Retweet & tag colleagues

#TumorBoardTuesday #OncTwitter #MedTwitter #GynCSM #gynonc

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RT @TumorBoardTues
2/#TumorBoardTuesday #OncTwitter #GynCSM #gynonc
#CME🔗http://bit.ly/3YRDkog

🟢#PreTest Q 1️⃣
📊Diarrhea, nausea, & vomiting are common GI toxicities associated w…
https://twitter.com/TumorBoardTues/status/1616204008028528643

5/#TumorBoardTuesday #BonumCE #OncTwitter #GynCSM #gynonc #EndometrialCancer
#CME 🔗http://bit.ly/3YRDkog

🟢#PreTest Q 4️⃣
📊During treatment w pembro + lenva, pt develops grade 3 HTN
🟢What is the most effective mgmt strategy for this patient? (CS = corticosteroid)

1/#TumorBoardTuesday #OncTwitter

🗓️TODAY🗓 w @DrMMurphy & @drteplinsky
🎥#EndometrialCancer - Mnging TKI/IO AEs

#CMEℹ️ http://bit.ly/3Vqtabi
Support by edu grants from Eisai & @Merck

🚨Be ready @ 8p ET/5p PT
✅Answer #PreTest👇
🔁RT & tag 🩺

🟢Where r u in your career?

Best part about working 5+ years as an attending is celebrating 5 year NED milestones with patients!

#radonc #OncTwitter

17/#TumorBoardTuesday #BonumCE #RenalCell
#OncTwitter #NephTwitter #MedTwitter

🔬Research needed to ⬇️ tox while maintaining efficacy

❓Alternative dosing strategies (incl. dose breaks)
❓Effects of dose ⬇️ on pt outcomes
❓Effects of reduced ▶️ dose on pt outcomes

15/ #TumorBoardTuesday #BonumCE #RenalCell
#OncTwitter #NephTwitter #MedTwitter

🟢Pt w mRCC
🔸Initiated tx w pembro + lenva
🔹Developed G3 diarrhea
🔸Lenva withheld & anti-diarrheal treatment initiated 🔹Diarrhea now resolved.

🟢What next step is best for the pt?

14/#TumorBoardTuesday #BonumCE #RenalCell
#OncTwitter #NephTwitter #MedTwitter

Effective tox mgmt ➡️optimize pt outcomes✅

🩺 Mgmt strategies include...🩺
🔹Prevention
🔸Monitor BP, urine protein, thyroid & liver function
🔹Dose modification (⏸️⬇️🛑)
🔸Supportive care

13/#TumorBoardTuesday #BonumCE #RenalCell
#OncTwitter #NephTwitter #MedTwitter

🔬Common tox in pivotal P3 #CHECKMATE214 trial of dual ICI combo🔬
🔸Fatigue
🔹Pruritus
🔸Diarrhea
🔹Rash
🔸Nausea

12/#TumorBoardTuesday #BonumCE #RenalCell
#OncTwitter #NephTwitter #MedTwitter

🔬Common tox in pivotal Phase 3 trials of TKI-ICI combos🔬
#KEYNOTE426 #CLEAR #CHECKMATE9ER #JAVELINrenal101
🔹Diarrhea
🔸HTN
🔹Hypothyroidism
🔸Fatigue
🔹PPES
🔸Loss of appetite

11/ #TumorBoardTuesday #BonumCE #RenalCell
#OncTwitter #NephTwitter #MedTwitter

Some AEs attributable to either drug
These🔂overlapping tox can complicate pt mgmt

10/ #TumorBoardTuesday #BonumCE #RenalCell
#OncTwitter #NephTwitter #MedTwitter

🟢Which of the following is an AE that is commonly observed with both ICIs and TKIs?

7/ #TumorBoardTuesday #BonumCE #RenalCell
#OncTwitter #NephTwitter #MedTwitter

🟢Which of the following is a characteristic feature of the most common toxicities associated with anti-angiogenic therapies?

6/ #TumorBoardTuesday #BonumCE #OncTwitter #NephTwitter #MedTwitter #RenalCell

✳️Dual ICI combo (ipi + nivo) also approved tx option

💎#CheckMate214 - ipi + nivo vs sunitinib
✅Longest follow-up in frontline RCC (>5 years)
✅OS and PFS favor combo tx in int/poor risk pts

4/ #TumorBoardTuesday #BonumCE #OncTwitter #RenalCell

💎Combo txs as SOC for 1st line mRCC💎

TKI/ICI combos:
🔸#lenvatinib (TKI) + #pembrolizumab (PD-1 mAb)
🔸#axitinib (TKI) + pembro
🔸#cabozantinib (TKI) + #nivolumab (PD-1 mAb)

Dual ICI combo:
🔸#ipilimumab (CTLA-4) + nivo

4/ #TumorBoardTuesday #BonumCE #OncTwitter #RenalCell

💎Combo txs as SOC for 1st line mRCC💎

TKI/ICI combos:
🔸#lenvatinib (TKI) + #pembrolizumab (PD-1 mAb)
🔸#axitinib (TKI) + pembro
🔸#cabozantinib (TKI) + #nivolumab (PD-1 mAb)

Dual ICI combo:
🔸#ipilimumab (CTLA-4) + nivo

4/ #TumorBoardTuesday #BonumCE #OncTwitter #RenalCell

💎Combo txs as SOC for 1st line mRCC💎

TKI/ICI combos:
🔸#lenvatinib (TKI) + #pembrolizumab (PD-1 mAb)
🔸#axitinib (TKI) + pembro
🔸#cabozantinib (TKI) + #nivolumab (PD-1 mAb)

Dual ICI combo:
🔸#ipilimumab (CTLA-4) + nivo

3/ #TumorBoardTuesday #BonumCE #RenalCell
#OncTwitter #NephTwitter #MedTwitter

🟢 Which of the following TKI/IO combo regimens is 🚫NOT approved by the FDA for the frontline mgmt of #RenalCell carcinoma?

2/ #TumorBoardTuesday #BonumCE #RenalCell #OncTwitter #NephTwitter
🆓#CME info ➕ full ref list🗒️ 👉 http://bit.ly/3VDaK81

✳️The critical elements👇

1/ #OncTwitter #NephTwitter #TumorBoardTuesday
✅#RenalCell #MedTweetorial🧵
w @brian_rini @shilpaonc @katy_beckermann

🦺TKI/IO safety data
🥽Tox to look 4
⛑AE mgmt

🆓#CME @BonumCe🔗http://bit.ly/3VDaK81
Support by edu grants from Eisai & @Merck

🟢What's your specialty?

📢 Let’s continue #LungCancerAwarenessMonth & join #TumorBoardTuesday!!

🥼@Latinamd @SamuelKareffMD bring us through treating #NSCLC with neoadju IO

Join us here!👇🏽

📱Weigh in how YOU’D treat
🧾Bring receipts
🙋Ask Q’s
📊check polls
🔁RT
👩🏻‍⚕️tag peers
@MPishvaian @JohnEbbenMDPhD
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RT @SamuelKareffMD
@TumorBoardTues 1/16 #TumorBoardTuesday #LungCancer #OncTwitter

69yo 👩🏻‍🦱
9 pk/yr tobacco - quit 34 years ago
3-4 months of cough & spu…
https://twitter.com/SamuelKareffMD/status/1592683889210032129