#nucleosome — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #nucleosome, aggregated by home.social.
-
Our new article has been published in the Biophysical Journal @BiophysJ: "Nucleosome spacing controls chromatin spatial structure and accessibility". We placed a long #nucleosome chain in a box mimicking natural density conditions. We did not see melting of #chromatin fibers at high densities. Accessibility of #chromatin to diffusive processes increases with higher regularity of nucleosome spacing. https://authors.elsevier.com/a/1ijrB1SPT7sCr. #hochschulestralsund #lmumünchen
-
Extensive multivalent interactions between intrinsically disordered regions in the #BRCA1/#BARD1 #E3 #ligase and #nucleosome substrates facilitate #chromatin recruitment and contribute to histone H2A #ubiquitylation and #DNArepair
Sam Witus, Rachel Klevit, Weixing Zhao et al
https://www.embopress.org/doi/10.15252/embj.2023113565