#nucleosome — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #nucleosome, aggregated by home.social.
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6/n In addition to the above shown examples for #MolecularMachines, here a few more #molecules we presented in #AugmentedReality at #IdeenExpo: #Tubulin-stathmin complex, #antibody, #nucleosome particle, #SARSCoV2 #polymerase.
#DIYbio #MINT #STEM #chem #AR #education #TiltFive -
Extensive multivalent interactions between intrinsically disordered regions in the #BRCA1/#BARD1 #E3 #ligase and #nucleosome substrates facilitate #chromatin recruitment and contribute to histone H2A #ubiquitylation and #DNArepair
Sam Witus, Rachel Klevit, Weixing Zhao et al
https://www.embopress.org/doi/10.15252/embj.2023113565 -
Our new preprint! Nucleosome repositioning in chronic lymphocytic leukaemia (CLL) https://www.biorxiv.org/content/10.1101/2022.12.20.518743v1
▶️Nucleosome changes at cancer-sensitive regions allow patient stratification
▶️Nucleosome repeat length (NRL) decreases with #cancer aggressiveness
▶️Interplay with #methylation, #TFbinding and more! -
#SingleCell multi-omics allows functional characterization of #structuralVariants https://www.nature.com/articles/s41587-022-01552-3 "We developed a computational method based on Strand-seq that combines #nucleosome occupancy and structural variation analysis in single cells to identify the functional effects of somatic structural variants in leukemia."