#nucleocapsid — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #nucleocapsid, aggregated by home.social.
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#SARSCoV2 has evolved to optimize its replication fitness in the human host. This study shows that a #nucleocapsid gene mutation enhances production of a truncated protein that boosts viral fitness by suppressing #antiviral responses @PLOSBiology https://plos.io/3PIZMjr
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#SARS-CoV-2 #papain-like #protease inhibits ISGylation of the viral #nucleocapsid protein to evade host anti-viral #immunity, J Virol.: https://journals.asm.org/doi/full/10.1128/jvi.00855-24?af=R
The present study may contribute to gaining new insight into the roles of ISGylation-mediated anti-viral function in SARS-CoV-2 infection and may lead to the development of more potent and selective inhibitors targeted to SARS-CoV-2 nucleocapsid protein.
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#Detection of #Nucleocapsid #Antibodies Associated with Primary #SARS-CoV-2 #Infection in Unvaccinated and Vaccinated #Blood #Donors, Emerg Infect Dis.: https://wwwnc.cdc.gov/eid/article/30/8/24-0659_article
Nucleocapsid antibody assays can be used to estimate SARS-CoV-2 infection #prevalence in regions implementing #spike-based COVID-19 #vaccines. We also found good durability of nucleocapsid antibody detection for up to >1 year after infection.