#novavax — Public Fediverse posts

#FDA green-lit updated #coronavirus #vaccines 4 higher-risk #Americans. Approved shots from vaccine manufacturers #Pfizer BioNTech & #Moderna which make #mRNA based vaccines, have an updated formulation aimed at better targeting coronavirus variants circulating around country. FDA also cleared updated vaccine from Sanofi, which doesn’t use mRNA-based tech & was originally licensed by #Novavax, The vaccines are expected to be available in the coming days. #publichealth #medicine #covid #health

I just got my #Novavax vaccine! No thanks to #RFKJrSucks ! 💉

#Covid19 #CovidVaccines #CovidIsntOver

Update: #Novavax is available at Costco in Scarborough!

Still no Novavax #CovidVaccines in #Maine yet. Hopefully, some will arrive soon (not that I'm putting away my masks any time soon). And yeah, I unfortunately have a condition that contraindicates mRNA vaccines.

#Covid19 #CovidIsntOver #RFKJrSucks

9/16/2024

Good Morning SARS2PAians!

Hope you are enjoying this beautiful weather. ☀️😎☀️

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VOCs

Still, nothing much has changed, the top two variants which also make up the bulk of random sequencing are KP.3.1.1 and KP.2.3.:https://ibb.co/9NJNYpj

XEC is still around, though in PA it's still at the bottom of the sequencing list and doesn't seem to be going anywhere.

There is a new variant that is being watched closely, and that is MV.1. It's shown to be potentially as fast as KP.3.1.1 with some very strange, little-understood mutations. It's a good competitor to KP.3.1.1 and while not very different from current variants, the actual mutations are very concerning because some are so rare.: https://ibb.co/XSRQXVX

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Wastewater

Wastewater levels are HIGH according to WastewaterSCAN, and CDC also considers them HIGH (not "Very High".): https://ibb.co/bmqSXvn

On the PA wastewater dashboard we're overall stable with some increases, but on WastewaterSCAN Harrisburg again is rising quickly, which shows a need for source control.: https://ibb.co/9wCTx3s

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That's all I have right now as I run out the door today! Please get those updated flu/COVID vaccinations, stay safe and we'll keep an eye on MV.1 together! 👀 👀 👀

#COVID19 #COVID #COVIDisNotOver #SARS2PA
#Pennsylvania #PA #KP3 #XEC #MV1

#Wastewater

#WearAMask #CleanTheAir #WashHands #mRNA #Novavax
#VaccinesSaveLives #StayHomeIfSick !

Good Afternoon SARS2PAians!

1/2 for Sept. 9th, 2024

I hope you are having a healthy and productive late summer!☀️

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VOCs

The national mutation leaderboard hasn't changed much.: https://ibb.co/LP1L4LZ

There are no new mutations that are on the far horizon that can compete with KP.3.1.1 so far.

The closest competitor is the recombinant XEC, a combo of KS.1.1 and KP.3.1, and is maybe almost equally as fast as what we have now.

We have XEC already in PA.: https://ibb.co/JpnYfcJ

The good news is XEC, as I mentioned last time, has only 2 spike mutations different from KP.3.1.1, so any immunity granted against KP.x.y will also work very well against XEC.

Actually, the current versions are pretty stagnant. Stagnation is good as it gives us a breather, but it's also what happened between XBB and JN.1/KP.x.y.: https://ibb.co/BCqrTFN

Thanks to variant hunters, who constantly monitor virus genetics and then estimate growth rates (and some of which are not even paid to do this for us), we will have a few weeks to a month or two of any incoming fast, binding, or immune-evasive mutations.

Keep watching that space. It's important, especially as winter approaches.

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Wastewater

WastewaterSCAN still has our region at HIGH levels of SARS2.: https://ibb.co/wRCwRkK

Chester's numbers are not low, but much more manageable than in other areas. Harrisburg is doing much better as numbers keep going down there! Good work Hburg!: https://ibb.co/Pm9kF4H

Our region's numbers are going down after a peak already. This is a relief. We are still the HHS region with the lowest numbers.: https://ibb.co/3zcRKJL

PA, after quite a sizeable spike, is VERy quickly returning to numbers way below national average and more on par with the rest of the region.: https://ibb.co/VtVxDYX

We're doing something right. 💪

But remember, numbers are still in the moderate to HIGH range, so please keep working on source control.

According to CDC, there is NO state right now having anything less than "moderate" wastewater levels. Clearly this is defintely NOT a best-case scenario going into Fall.

Existing immune deficiency due to previous reinfections (and first time infections!) and already very high virus spread might make for quite a high-maintenance Fall and Winter this year.

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Kits, vaxes, etc.

Reminder that you can get 4 Federally funded tests kits by mail at the end of this month. Don't miss it!!

Covidtests.gov: https://aspr.hhs.gov/covid-19/test/Pages/default.aspx

There's also a tool from Vaccines.gov to find an mRNA KP.2 vaccination near you!!!

🔴Also reminder: if you have an uncomfortably strong reaction to mRNA vaccines, please do give Novavax a try. It's protein-based, and formulated much like a traditional tetanus shot, rather than mRNA.

https://us.novavaxcovidvaccine.com/find-a-vaccine

I am not in any way paid to promote Novavax. And I'm not the company President, but...I am in fact a client 😎

If you are unable to get Novavax, PLEASE.....get something.

🔴And gooooooo get a FLU SHOT too if you are able!

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Other Pathogens

:coronavirus: H5N1

There was a first case already of H5N1 infection in a person in Missouri, NOT linked, so far, to animal contact and not farm related.

https://www.cnn.com/2024/09/06/health/first-human-case-of-bird-flu-not-linked-to-animals/index.html

This is the current picture for H5N1. Found in 14 states.: https://ibb.co/pfrFxtT

This is ...pretty bad. This is getting progressively...kinda bad.

🔴Please DO NOT consume raw dairy products: raw eggs, undercooked/rare meat, unpasteurized dairy. Dippy eggs. Raw egg-based cookie dough. Just don't.

🔴Use extra caution with animals like rodents in your home, especially if you have to deal with them after they're trapped.

🔴Keep your cats indoors and dogs away from prey. H5N1 has a super-high kill rate especially in cats.

Stock up NOW on a few N95s (you will NOT want less than a genuine N95 for this thing), gloves, and MERV-13 filters for those CR boxes.

CDC can repeat "risk assessment low" all they want, we should NOT be screwing around with something than has an estimated baseline 20% kill rate, which is the reason I spend so much time on this subject in a SARS2 forum.

The current genetics of H5N1 is not scary, but giving this thing more chances to hit the lottery is the worst thing we could be doing now.

🔴Again: H5N1 cannot combine with the pathogen that causes COVID19, because one is a SARS and the other is an influenza. They are way too different from each other. But it CAN combine with influenza A and B....and we are entering that season soon.

We can do the best things in preparation NOW for a worst case scenario which means building up some basic PPE at home, avoiding exposure. Prepare =/= panic.

Please stay safe this coming Fall and keep that source control down!

☀️🍁☀️

#COVID19 #COVID #COVIDisNotOver #SARS2PA
#Pennsylvania #PA #KP3 #XEC #FLuQUE

#Wastewater #Norovirus #Noro

#H5N1 #HPAI #BirdFlu

#WearAMask #CleanTheAir #WashHands #mRNA #Novavax
#VaccinesSaveLives #StayHomeIfSick !

Good Muggy Morning SARS2PAians! ☁️💐☁️

I hope you are having a safe Spring!

#VOCs

The top news lately are the newest variants causing country-wide summer waves including Spain: https://ibb.co/hRpvjt5

and Portugal: https://ibb.co/khTtyJX

They are KP.3.x.y and LB.x.y.

These new immune evasive variants are filling up hospitals and causing notable increases in deaths.

KP.3 is now the variant "grandfather" that is the fastest, the most immune evasive, and the most easily bound to cells. Specifically, the most watched upcoming variant is its grandchild, KP.3.1.1.

The newest variants that have a very good chance of causing a sizeable increase in numbers, if not a full blown-out wave, are variants of KP.3 that already have immune evasive mutations (FLuQE) but also have an advantageous specific spike deletion (S:S31del).

These new and fastest variants are immune evasive to BOTH current vaccinations, AND prior infections.

Nationally, KP.2 is still just barely at the top of the leaderboard. KP.2.3 is right behind it, already a variant that is being watched.: https://ibb.co/p0d8G8n

🔴KP.3.1.1 is absolutely blazing fast and burning through Spain, Portugal and other countries, and is part of KP-DEL31.

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NOTE: "KP-DEL31" is gonna be my nickname for it, not variant hunters or virologists. Just to call it something easily condensed and recognizeable for now. They might decide on a different nickname soon. These names are just for convenience. (You don't call your cousin Mister James Robert Smith every time, do you? You call him JimBob or Smitty. It just makes talking easier.)

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I've highlighted FLiRT in pink on the national screenshot but I'll drop it soon as KP-DEL31 becomes more and more relevant.

There's no specific results for PA on the Tableau site. Probably not enough testing here.

In NY/NJ, I've highlighted KP-DEL31 in green on the NY/NJ leaderboard, and as you can see, all the top 5 variants there have this very important spike deletion. But KP.3.1.1 is the variant to keep eyes on.: https://ibb.co/Jcv0rF7

KP.3.1.1 is already found (in only a few days!) in TX, NY, CA, CO, NJ, WA, and VA.

🔴If you've dropped wearing respirators for now you might want to reconsider putting them back on as KP.3.1.1 makes gains and spring moves along.

________________

#Wastewater

Wastewater has returned to HIGH levels in the Eastern and Southern states. KP.2, KP.3 and LB.x.y variants are working together on driving this.: https://ibb.co/0nHqQPS

In our region, specifically testing in Maryland is showing a return to higher levels.: https://ibb.co/99MSpy0

The PA wastewater dashboard is showing LARGE increases in Philly, and sizeable increases in Centre and Indiana counties.: https://ibb.co/0J14Tty

MASK UP, oh my Philly ❤️️!

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#Vaccines

Whoa I had a whole angry thing typed out here and juuuuuuust checked back on Twitter, and Dr. Eric Topol wrote just 2 hrs ago that the US FDA has changed its decision for the upcoming vaccine base!!: https://ibb.co/xzB6GVb

The newest mRNA vaccines will be based on KP.2 and NOT JN.1!

This is a wise decision and fantastic news!!

This will certainly better prepare us for Summer.

(NOTE: **Novavax** will have a JN.1 based booster. Novavax is completely different as it has proven effective through multiple years with ONE base so that vaccine will probably not have to be changed as often.)

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🔴Even with vaccines, there are always other things we can do to practice source control!

keep those windows OPEN

wear a respirator

keep the air clean

move meetings outside

work from home

build a Corsi-Rosenthal box

stay home if you are sick!

Continue to have a great and safe Spring!! 💐💐💐

#COVID19 #COVID #COVIDisNotOver #SARS2PA #Pennsylvania #PA
#FLiRT #F456L #R346T #spike_f456l #spike_r346t
#FLuQE #Q493E
#KP2 #KP3 #LB1 #Moderna #Pfizer #Novavax
#WearAMask #CleanTheAir #WashHands #VaccinesSaveLives #StayHomeIfSick !