#nephpearls — Public Fediverse posts

Hyponatremia: Treatment standard 2024 #Nephpearls :renal:

👉🏼 https://pubmed.ncbi.nlm.nih.gov/39009016/

Linezolid-induced lactic acidosis ca. 2024
#Nephpearls :renal:

👉🏼 https://www.renalfellow.org/2024/05/02/skeleton-key-group-case-33-atrocious-acidosis/

Updated Review of Membranous Nephropathy ca. 2024
#Nephpearls :renal:

👉🏼 https://indianjnephrol.org/an-updated-review-of-membranous-nephropathy

Check out this tweetorial on “The Canary in the Coal Mine of Kidney and Cardiovascular Disease”
#Nephpearls :renal:
#Cardiorenal :heart_anatomical: :renal:

👉🏼 https://x.com/ckd_ce/status/1775478543616553129?s=46&t=Q9LXl0TLttUy1j3Ms74AXA

Not all ARBs are created equal
#Nephpearls :renal: :BP_cuff:

👉🏼 https://pubmed.ncbi.nlm.nih.gov/17563549/

Check out the latest Channel Your Enthusiasm Podcasts 🎧 covering Chapter 14: Hypovolemic states #Nephpearls :renal:

👉🏼 Part 1 http://www.rosebook.club/episodes/2023/2/12/chapter-fourteen

👉🏼 Part 2 📢 20th Podcast http://www.rosebook.club/episodes/2024/3/24/chapter-fourteen-part-2

Diabetic Kidney Disease: What Does It Mean For Patients?
#WorldKidneyDay #Nephpearls :renal:

🎧 Webinar March 14, 2024
⏰ 12:00 pm to 1:00 pm EDT

👉🏼 https://nephu.org/event/diabetic-kidney-disease-what-does-it-mean-for-patients-03142024-firstsession/

KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of CKD
#WorldKidneyDay 2️⃣🌐2️⃣4️⃣ #Nephpearls

👉🏼 https://kdigo.org/guidelines/ckd-evaluation-and-management/

Plasma Exchange (PLEX) for ANCA-Associated Vasculitis (AAV) ca. 2024 KDIGO
#Nephpearls :renal:

📌 Those with serum creatinine >3.4 mg/dL, requiring dialysis or with rapidly increasing serum creatinine, diffuse alveolar hemorrhage (DAH) with hypoxemia

📌 Those with an overlap syndrome of AAV and anti-GBM

👉🏼 https://kdigo.org/guidelines/antineutrophilic-cytoplasmic-antibody-anca-associated-vasculitis-aav

KDIGO Clinical Practice Guideline for the Management of Antineutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis ca. 2024 #Nephpearls :renal:

📌 Diagnosis
📌 Treatment algorithm

👉🏼 https://kdigo.org/guidelines/antineutrophilic-cytoplasmic-antibody-anca-associated-vasculitis-aav/

Urgent start PD
#Nephpearls :renal:

👉🏼 https://link.springer.com/book/10.1007/978-3-030-70897-9

Which patients with CKD are candidates for SGLT2 inhibitors: Cold 🥶 Map #Nephpearls :renal:

Rituximab Resistance in Glomerular Diseases: A GlomCon Mini-Review ca. 2024 #Nephpearls :renal:

📌 Mechanisms of rituximab resistance
📌 Clinical approach to diagnosis and management of rituximab resistance

👉🏼 https://www.kidneymedicinejournal.org/article/S2590-0595(24)00002-5/fulltext

Spectrum of glomerular diseases
#Nephpearls :renal:

👉🏼 https://shop.lww.com/Handbook-of-Glomerulonephritis/p/9781975191061

Cushing Syndrome: Diagnosis
#Nephpearls :renal:
#HTNSecrets :BP_cuff:

📌 1-mg dexamethasone suppression test: commonly used as an initial screening test, particularly in patients with incidentally found adrenal nodules

👉 https://www.us.elsevierhealth.com/hypertension-secrets-9780323758529.html

Primary Aldosteronism: Diagnostic algorithm
1⃣ Screening
2⃣ Confirmation
3⃣ Subtype Classification
#Nephpearls :renal:
#HTNSecrets :BP_cuff:

👉 https://www.us.elsevierhealth.com/hypertension-secrets-9780323758529.html

Role of Different Antihypertensive Drug Classes in Treatment of Hypertension in Patients with ESKD
#HTNSecrets :BP_cuff:
#Nephpearls :renal:

👉 https://www.us.elsevierhealth.com/hypertension-secrets-9780323758529.html

Additive effects of dapagliflozin ➕ finerenone on albuminuria in non-diabetic CKD: an open-label randomized clinical trial ca. 2024
#Nephpearls :renal:

👉🏼 https://academic.oup.com/ckj/article/17/1/sfad249/7283166

Rhabdomyolysis induced AKI: Key 🔑 pathobiological processes :nephron: and management interventions ca. 2023
#Nephpearls :renal:

👉🏼 https://journals.lww.com/cjasn/pages/articleviewer.aspx?year=9900&issue=00000&article=00286&type=Fulltext

A step-by-step algorithm for the optimal assessment and management of hypertension :BP_cuff: among patients on dialysis ca. 2024
#Nephpearls :renal:

👉🏼 https://journals.lww.com/jasn/abstract/9900/resistant_hypertension_in_dialysis__epidemiology,.239.aspx

NephJC’s Top Nephrology Stories for 2023 #Nephpearls :renal:

👉🏼 http://www.nephjc.com/news/2024/1/15/top-stories-in-nephrology-2023

Tumor Lysis Syndrome ca. 2023
#Nephpearls :renal:
#Onconephrology🦀

👉🏼 https://journals.lww.com/cjasn/pages/articleviewer.aspx?year=2023&issue=12000&article=00020&type=Fulltext

Genetic causes of hypertension
#Nephpearls :renal:
#HTNSecrets :BP_cuff:

👉 https://www.us.elsevierhealth.com/hypertension-secrets-9780323758529.html

Guide to Familial Hypertension syndromes
#Nephpearls :renal:
#HTNSecrets :BP_cuff:

👉 https://www.renalfellow.org/2018/11/19/raas-is-your-friend-pocket-guide-to-heritable-blood-pressure/

Toxic Alcohol Ingestions: Clinical Features, Diagnosis, and Management ca. 2008
#Nephpearls :renal:

👉🏼 https://journals.lww.com/cjasn/pages/articleviewer.aspx?year=2008&issue=01000&article=00035&type=Fulltext

Poisonings and intoxications #Nephpearls :renal:

Hypocomplementemia #Nephpearls :renal:

🧪 C3 levels can be decreased by complement activation through any of the 3 pathways (classical, alternative, or lectin)

🧪 Low C4 levels are generally indicative of activation through the classical pathway

👉🏼 https://shop.lww.com/Handbook-of-Glomerulonephritis/p/9781975191061

Hypertension, Hypokalemia and Metabolic Alkalosis
#Nephpearls :renal:

👉🏼 https://journals.lww.com/cjasn/pages/articleviewer.aspx?year=2023&issue=07000&article=00022&type=Fulltext

KDIGO 2024 Clinical Practice Guideline for the Management of Lupus Nephritis
#Nephpearls :renal: 🦋

📌 Immunosuppressive treatment for patients with Class I or Class II lupus nephritis
📌 Recommended approach for initial therapy of active Class III/IV lupus nephritis
📌 Recommended options of maintenance therapy for Class III and Class IV lupus nephritis
📌 Management of patients with pure Class V lupus nephritis

👉 https://www.kidney-international.org/article/S0085-2538(23)00627-0/fulltext

Holistic approach to chronic kidney disease (CKD) treatment and risk modification from KDIGO
#Nephpearls :renal:

👉🏼 https://kdigo.org/guidelines/ckd-evaluation-and-management/

Minimal Change Disease (MCD): Treatment from KDIGO
#Nephpearls :renal:

👉 kdigo.org/guidelines/gd/

KDIGO Clinical Practice Guideline for Diabetes Management in CKD recommends annual monitoring patients for vitamin B12 deficiency when treated with metformin for > 4 years #Nephpearls :renal:
👉 https://kdigo.org/guidelines/diabetes-ckd/

KDIGO has updated the 2012 Clinical Practice Guideline for the Evaluation & Management of CKD #Nephpearls :renal:

✅ The KDIGO 2023 CKD Guideline is now available for public review

Kindly submit your feedback no later than Monday, July 24th 🗓️

👉🏼 https://kdigo.org/guidelines/ckd-evaluation-and-management/

ADVOR: The addition of acetazolamide to loop diuretic therapy in patients with acute decompensated heart failure resulted in a greater incidence of successful decongestion ca. 2022
#Cardiorenal :heart_anatomical: :renal:
#Nephpearls :renal:

👉🏼 https://www.nejm.org/doi/full/10.1056/NEJMoa2203094

Delta ratio = (change in anion gap)/(change in bicarbonate)
#Nephpearls :renal:

< 0.4: Normal AG acidosis
0.4-0.8: Mixed high ➕ normal AG acidosis
0.8-2.0: Pure high AG acidosis
> 2.0: High AG acidosis ➕ pre-existing metabolic alkalosis

👉🏼 pubmed.ncbi.nlm.nih.gov/17656477/

Toxic Alcohols #Nephpearls :renal:

Volume Management with Kidney Replacement Therapy in the Critically Ill Patient ca. 2023 from
#Nephpearls :renal:

👉🏼 https://pubmed.ncbi.nlm.nih.gov/37016472/

Large (?largest) IgG4 cohort study published in #CJASN
https://journals.lww.com/cjasn/Abstract/9900/Clinical_and_Prognostic_Factors_in_Patients_with.162.aspx
#NephPearls

The many colors 🌈 of urine
#Nephpearls :renal: #NephSecrets :renal:

👉🏼 https://www.clinicalkey.com/#!/browse/book/3-s2.0-C20150066047

1. Hígado. 2. Riñón. 4. Líquido-ascitis. 3…
Mal rollo ☹️ Lo que me gusta #POCUS 😃😍
---
RT @NephroP
#POCUS quiz
What are 1, 2, 3 and 4?
Approximate transducer location shown.
#MedEd #IMPOCUS #Nephpearls
https://twitter.com/NephroP/status/1643072142618271744

Light chain nephropathy: how to treat? #OpenAccess review from the Mayo

https://www.nature.com/articles/s41408-023-00806-w

#Free #NephPearls #Myeloma #AKI

KDIGO is updating the 2021 Glomerular Diseases (GD) Guideline on an ongoing, chapter-by-chapter basis

📢 The KDIGO 2023 Lupus Nephritis Guideline is now available for public review

We invite you to review the guideline chapter update #Nephpearls

👉🏼 https://kdigo.org/guidelines/gd/

SGLT2 inhibitors in CKD ca. 2023
#Nephpearls :renal:

👉🏼 https://www.kidneymedicinejournal.org/article/S2590-0595(23)00012-2/fulltext

Kidney Transplantation 101: Metabolic changes post-transplantation ca. 2021
#Nephpearls :renal:

👉🏼 pubmed.ncbi.nlm.nih.gov/34307432/

Updates in #Onconephrology 🦀 ca. 2023
#Nephpearls :renal:

👉🏼 https://journals.lww.com/kidney360/pages/articleviewer.aspx?year=2023&issue=02000&article=00019&type=Fulltext

Sepsis associated AKI: Consensus paper ca. 2023
#Nephpearls :renal:

👉🏼 https://www.nature.com/articles/s41581-023-00683-3

AKI in patients with cirrhosis ca. 2023
#Nephpearls :renal:
#Hepatorenal :liver: :renal:

👉🏼 https://www.nejm.org/doi/full/10.1056/NEJMra2215289

cool case discussion on #GFR in people with #Black ethicities in UK
#KidneyFunction
https://www.bmj.com/content/380/bmj-2022-073353.short?rss=1

$gated of course

Interesting as Europe = we don't like CKD-EPI, we prefer EKFC

NICE = CKD-EPI 2009 without race correction

#NephPearls

for your reading pleasure: a review on #Magnesium and #BoneHealth
Gen pop vs #dialysis
https://journals.sagepub.com/doi/full/10.1177/20543581231154183
#OpenAccess and #Free
#NephPearls

Membranous Nephropathy: Mapping antigens ca. 2023
#Nephpearls :renal:

👉🏼 https://www.kidney-international.org/article/S0085-2538(23)00007-8/fulltext?dgcid=raven_jbs_etoc_email#.Y_TegKg-E2g.twitter

Valuable resource for those who follow CKD #Nephpearls :renal:

H/T @Kidney_boy for sharing this 🧮

👉🏼 https://www.ckdpc.org/risk-models.html

@alexchangmd @hswapnil I guess I'd call this tertiary hyperparathyroidism, because of the hypercalcaemia. PTH should be suppressed for any other cause of hypercalcaemia, though that isa pathophysiology argument not one I can support with evidence. I think you've done due diligence for now diagnostically. Are you thinking of using bisphosphonate IV or only of hypercalcaemia worsens?

PS for others to have a chance of seeing and weighing in, which would be great, would value other #nephpearls #kidneyverse opinions, on Mastodon you have to reblog/boost. Unlike the birdsite, there's no algorithm that responds to likes, it just tells the person posting that you liked it.

Very nice to meet you and what an interesting post!

Transplant 101: Cyclosporine vs Tacrolimus
#Nephpearls :renal:

👉🏼 https://www.sciencedirect.com/science/article/pii/S1548559519301466

Renalism: The failure to perform appropriate diagnostic/ therapeutic interventions in patients with CKD due to concern about risk of AKI
#Nephpearls :renal:

👉🏼 https://pubmed.ncbi.nlm.nih.gov/15339996/

Hepatorenal Syndrome: Current Concepts and Challenges
#Nephpearls :renal:

https://www.renalfellow.org/2021/07/15/hepatorenal-syndrome-current-concepts-and-challenges/

Hyponatremia: Diagnostic algorithm
#Nephpearls :renal:

👉🏼 https://shop.lww.com/Handbook-of-Critical-Care-Nephrology/p/9781975144098

Anti-GBM Glomerulonephritis
#Nephpearls :renal:

🔬 Crescents (at similar stages) w/ segmental glomerular necrosis
🔬 Linear staining of GBMs by IF for IgG, & pseudolinear or granular C3 staining
🔬 Absence of deposits by EM

👉🏼 https://kdigo.org/wp-content/uploads/2022/02/KDIGO-Arkana-Pathology-Slide-Set-2022_KDIGO-GD-Guideline.pptx

@edgarvlermamd seeing Lerma bring #NephPearls to Mastodon is making it feel like home.

Genetic causes of hypertension
#HTNSecrets #Nephpearls

👉🏼 https://www.us.elsevierhealth.com/hypertension-secrets-9780323758529.html

Renal Denervation: Are We There Yet ca. 2022
#Nephpearls :renal:

https://ajkdblog.org/2022/12/21/renal-denervation-are-we-there-yet/