#nais — Public Fediverse posts

#Genotypic & #phenotypic susceptibility of emerging avian #influenza A viruses to
#NAIs & cap-dependent endonuclease #inhibitors, Antiviral Res.: https://www.sciencedirect.com/science/article/pii/S0166354224001682?via%3Dihub

Frequencies of markers of resistance to antivirals were low among >20,000 avian influenza A viruses studied. #H5Nx, #H7Nx, & #H9N2 viruses were susceptible to sub-nanomolar concentrations of antivirals. NA-I222M, but not NA-S246N or NA-I222V, in H5N1 confers reduced inhibition by #oseltamivir.

#Genotypic & #phenotypic susceptibility of emerging avian #influenza A viruses to
#NAIs & cap-dependent endonuclease #inhibitors, Antiviral Res.: https://www.sciencedirect.com/science/article/pii/S0166354224001682?via%3Dihub

Frequencies of markers of resistance to antivirals were low among >20,000 avian influenza A viruses studied. #H5Nx, #H7Nx, & #H9N2 viruses were susceptible to sub-nanomolar concentrations of antivirals. NA-I222M, but not NA-S246N or NA-I222V, in H5N1 confers reduced inhibition by #oseltamivir.

#Genotypic & #phenotypic susceptibility of emerging avian #influenza A viruses to
#NAIs & cap-dependent endonuclease #inhibitors, Antiviral Res.: https://www.sciencedirect.com/science/article/pii/S0166354224001682?via%3Dihub

Frequencies of markers of resistance to antivirals were low among >20,000 avian influenza A viruses studied. #H5Nx, #H7Nx, & #H9N2 viruses were susceptible to sub-nanomolar concentrations of antivirals. NA-I222M, but not NA-S246N or NA-I222V, in H5N1 confers reduced inhibition by #oseltamivir.

#Genotypic & #phenotypic susceptibility of emerging avian #influenza A viruses to
#NAIs & cap-dependent endonuclease #inhibitors, Antiviral Res.: https://www.sciencedirect.com/science/article/pii/S0166354224001682?via%3Dihub

Frequencies of markers of resistance to antivirals were low among >20,000 avian influenza A viruses studied. #H5Nx, #H7Nx, & #H9N2 viruses were susceptible to sub-nanomolar concentrations of antivirals. NA-I222M, but not NA-S246N or NA-I222V, in H5N1 confers reduced inhibition by #oseltamivir.

#Genotypic & #phenotypic susceptibility of emerging avian #influenza A viruses to
#NAIs & cap-dependent endonuclease #inhibitors, Antiviral Res.: https://www.sciencedirect.com/science/article/pii/S0166354224001682?via%3Dihub

Frequencies of markers of resistance to antivirals were low among >20,000 avian influenza A viruses studied. #H5Nx, #H7Nx, & #H9N2 viruses were susceptible to sub-nanomolar concentrations of antivirals. NA-I222M, but not NA-S246N or NA-I222V, in H5N1 confers reduced inhibition by #oseltamivir.

#Virological and #clinical #outcomes in outpatients treated with #baloxavir or #NAIs for A(#H3N2) #influenza: A multicenter study of the 2022-2023 season https://pubmed.ncbi.nlm.nih.gov/38430970/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=10ykRO9og5pGdo51l9DEPEpOJ3DVFIn__QK2QPM3dci1C1dEYq&fc=None&ff=20240303191922&v=2.18.0.post9+e462414

-- These findings affirm baloxavir's virological and clinical effectiveness against A(H3N2) in the 2022-2023 season and suggest limited clinical influence of post-treatment resistance emergence.

#Virological and #clinical #outcomes in outpatients treated with #baloxavir or #NAIs for A(#H3N2) #influenza: A multicenter study of the 2022-2023 season https://pubmed.ncbi.nlm.nih.gov/38430970/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=10ykRO9og5pGdo51l9DEPEpOJ3DVFIn__QK2QPM3dci1C1dEYq&fc=None&ff=20240303191922&v=2.18.0.post9+e462414

-- These findings affirm baloxavir's virological and clinical effectiveness against A(H3N2) in the 2022-2023 season and suggest limited clinical influence of post-treatment resistance emergence.

#Russia, According to genetic #analysis conducted in St. Petersburg, 9 A #H1N1pdm09 {#influenza} viruses had the H275Y #substitution in #neuraminidase responsible for resistance to #oseltamivir. NIC: https://www.influenza.spb.ru/en/influenza_surveillance_system_in_russia/epidemic_situation/ #antivirals #NAIs

#Russia, According to genetic #analysis conducted in St. Petersburg, 9 A #H1N1pdm09 {#influenza} viruses had the H275Y #substitution in #neuraminidase responsible for resistance to #oseltamivir. NIC: https://www.influenza.spb.ru/en/influenza_surveillance_system_in_russia/epidemic_situation/ #antivirals #NAIs

''In 2022, flu #H3N2 viruses predominated over #H1N1pdm09 & B viruses, accounting for 77% of all viruses analysed. Majority of #H1N1pdm09, #H3N2 & flu B viruses analysed at Centre were found to be antigenically and genetically similar to respective #WHO recommended #vaccine #strains for the S hemisphere in 2022. Of 3,372 samples tested for susceptibility to the #NAIs #oseltamivir & #zanamivir, 2 H1N1pdm09 viruses showed highly reduced inhibition against oseltamivir.''

''In 2022, flu #H3N2 viruses predominated over #H1N1pdm09 & B viruses, accounting for 77% of all viruses analysed. Majority of #H1N1pdm09, #H3N2 & flu B viruses analysed at Centre were found to be antigenically and genetically similar to respective #WHO recommended #vaccine #strains for the S hemisphere in 2022. Of 3,372 samples tested for susceptibility to the #NAIs #oseltamivir & #zanamivir, 2 H1N1pdm09 viruses showed highly reduced inhibition against oseltamivir.''

#Efficacy of #favipiravir against #influenza virus #resistant to both #baloxavir and #NAIs, J Antimicrob Chemother., https://doi.org/10.1093/jac/dkad145

#Efficacy of #favipiravir against #influenza virus #resistant to both #baloxavir and #NAIs, J Antimicrob Chemother., https://doi.org/10.1093/jac/dkad145

#Efficacy of #favipiravir against #influenza virus #resistant to both #baloxavir and #NAIs, J Antimicrob Chemother., https://doi.org/10.1093/jac/dkad145

#Efficacy of #favipiravir against #influenza virus #resistant to both #baloxavir and #NAIs, J Antimicrob Chemother., https://doi.org/10.1093/jac/dkad145

#Efficacy of #favipiravir against #influenza virus #resistant to both #baloxavir and #NAIs, J Antimicrob Chemother., https://doi.org/10.1093/jac/dkad145

I'm wondering if there's a hashtag for #educators in #k12 #independentschool #privateschool settings. #NAIS
#edutooter