#nais — Public Fediverse posts

#Genotypic & #phenotypic susceptibility of emerging avian #influenza A viruses to
#NAIs & cap-dependent endonuclease #inhibitors, Antiviral Res.: https://www.sciencedirect.com/science/article/pii/S0166354224001682?via%3Dihub

Frequencies of markers of resistance to antivirals were low among >20,000 avian influenza A viruses studied. #H5Nx, #H7Nx, & #H9N2 viruses were susceptible to sub-nanomolar concentrations of antivirals. NA-I222M, but not NA-S246N or NA-I222V, in H5N1 confers reduced inhibition by #oseltamivir.

#Genotypic & #phenotypic susceptibility of emerging avian #influenza A viruses to
#NAIs & cap-dependent endonuclease #inhibitors, Antiviral Res.: https://www.sciencedirect.com/science/article/pii/S0166354224001682?via%3Dihub

Frequencies of markers of resistance to antivirals were low among >20,000 avian influenza A viruses studied. #H5Nx, #H7Nx, & #H9N2 viruses were susceptible to sub-nanomolar concentrations of antivirals. NA-I222M, but not NA-S246N or NA-I222V, in H5N1 confers reduced inhibition by #oseltamivir.

#Genotypic & #phenotypic susceptibility of emerging avian #influenza A viruses to
#NAIs & cap-dependent endonuclease #inhibitors, Antiviral Res.: https://www.sciencedirect.com/science/article/pii/S0166354224001682?via%3Dihub

Frequencies of markers of resistance to antivirals were low among >20,000 avian influenza A viruses studied. #H5Nx, #H7Nx, & #H9N2 viruses were susceptible to sub-nanomolar concentrations of antivirals. NA-I222M, but not NA-S246N or NA-I222V, in H5N1 confers reduced inhibition by #oseltamivir.

#Genotypic & #phenotypic susceptibility of emerging avian #influenza A viruses to
#NAIs & cap-dependent endonuclease #inhibitors, Antiviral Res.: https://www.sciencedirect.com/science/article/pii/S0166354224001682?via%3Dihub

Frequencies of markers of resistance to antivirals were low among >20,000 avian influenza A viruses studied. #H5Nx, #H7Nx, & #H9N2 viruses were susceptible to sub-nanomolar concentrations of antivirals. NA-I222M, but not NA-S246N or NA-I222V, in H5N1 confers reduced inhibition by #oseltamivir.

#Genotypic & #phenotypic susceptibility of emerging avian #influenza A viruses to
#NAIs & cap-dependent endonuclease #inhibitors, Antiviral Res.: https://www.sciencedirect.com/science/article/pii/S0166354224001682?via%3Dihub

Frequencies of markers of resistance to antivirals were low among >20,000 avian influenza A viruses studied. #H5Nx, #H7Nx, & #H9N2 viruses were susceptible to sub-nanomolar concentrations of antivirals. NA-I222M, but not NA-S246N or NA-I222V, in H5N1 confers reduced inhibition by #oseltamivir.

#Virological and #clinical #outcomes in outpatients treated with #baloxavir or #NAIs for A(#H3N2) #influenza: A multicenter study of the 2022-2023 season https://pubmed.ncbi.nlm.nih.gov/38430970/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=10ykRO9og5pGdo51l9DEPEpOJ3DVFIn__QK2QPM3dci1C1dEYq&fc=None&ff=20240303191922&v=2.18.0.post9+e462414

-- These findings affirm baloxavir's virological and clinical effectiveness against A(H3N2) in the 2022-2023 season and suggest limited clinical influence of post-treatment resistance emergence.

#Virological and #clinical #outcomes in outpatients treated with #baloxavir or #NAIs for A(#H3N2) #influenza: A multicenter study of the 2022-2023 season https://pubmed.ncbi.nlm.nih.gov/38430970/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=10ykRO9og5pGdo51l9DEPEpOJ3DVFIn__QK2QPM3dci1C1dEYq&fc=None&ff=20240303191922&v=2.18.0.post9+e462414

-- These findings affirm baloxavir's virological and clinical effectiveness against A(H3N2) in the 2022-2023 season and suggest limited clinical influence of post-treatment resistance emergence.

#Virological and #clinical #outcomes in outpatients treated with #baloxavir or #NAIs for A(#H3N2) #influenza: A multicenter study of the 2022-2023 season https://pubmed.ncbi.nlm.nih.gov/38430970/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=10ykRO9og5pGdo51l9DEPEpOJ3DVFIn__QK2QPM3dci1C1dEYq&fc=None&ff=20240303191922&v=2.18.0.post9+e462414

-- These findings affirm baloxavir's virological and clinical effectiveness against A(H3N2) in the 2022-2023 season and suggest limited clinical influence of post-treatment resistance emergence.

#Russia, According to genetic #analysis conducted in St. Petersburg, 9 A #H1N1pdm09 {#influenza} viruses had the H275Y #substitution in #neuraminidase responsible for resistance to #oseltamivir. NIC: https://www.influenza.spb.ru/en/influenza_surveillance_system_in_russia/epidemic_situation/ #antivirals #NAIs

#Russia, According to genetic #analysis conducted in St. Petersburg, 9 A #H1N1pdm09 {#influenza} viruses had the H275Y #substitution in #neuraminidase responsible for resistance to #oseltamivir. NIC: https://www.influenza.spb.ru/en/influenza_surveillance_system_in_russia/epidemic_situation/ #antivirals #NAIs

#Russia, According to genetic #analysis conducted in St. Petersburg, 9 A #H1N1pdm09 {#influenza} viruses had the H275Y #substitution in #neuraminidase responsible for resistance to #oseltamivir. NIC: https://www.influenza.spb.ru/en/influenza_surveillance_system_in_russia/epidemic_situation/ #antivirals #NAIs

''In 2022, flu #H3N2 viruses predominated over #H1N1pdm09 & B viruses, accounting for 77% of all viruses analysed. Majority of #H1N1pdm09, #H3N2 & flu B viruses analysed at Centre were found to be antigenically and genetically similar to respective #WHO recommended #vaccine #strains for the S hemisphere in 2022. Of 3,372 samples tested for susceptibility to the #NAIs #oseltamivir & #zanamivir, 2 H1N1pdm09 viruses showed highly reduced inhibition against oseltamivir.''

''In 2022, flu #H3N2 viruses predominated over #H1N1pdm09 & B viruses, accounting for 77% of all viruses analysed. Majority of #H1N1pdm09, #H3N2 & flu B viruses analysed at Centre were found to be antigenically and genetically similar to respective #WHO recommended #vaccine #strains for the S hemisphere in 2022. Of 3,372 samples tested for susceptibility to the #NAIs #oseltamivir & #zanamivir, 2 H1N1pdm09 viruses showed highly reduced inhibition against oseltamivir.''

''In 2022, flu #H3N2 viruses predominated over #H1N1pdm09 & B viruses, accounting for 77% of all viruses analysed. Majority of #H1N1pdm09, #H3N2 & flu B viruses analysed at Centre were found to be antigenically and genetically similar to respective #WHO recommended #vaccine #strains for the S hemisphere in 2022. Of 3,372 samples tested for susceptibility to the #NAIs #oseltamivir & #zanamivir, 2 H1N1pdm09 viruses showed highly reduced inhibition against oseltamivir.''

''In 2022, flu #H3N2 viruses predominated over #H1N1pdm09 & B viruses, accounting for 77% of all viruses analysed. Majority of #H1N1pdm09, #H3N2 & flu B viruses analysed at Centre were found to be antigenically and genetically similar to respective #WHO recommended #vaccine #strains for the S hemisphere in 2022. Of 3,372 samples tested for susceptibility to the #NAIs #oseltamivir & #zanamivir, 2 H1N1pdm09 viruses showed highly reduced inhibition against oseltamivir.''

''In 2022, flu #H3N2 viruses predominated over #H1N1pdm09 & B viruses, accounting for 77% of all viruses analysed. Majority of #H1N1pdm09, #H3N2 & flu B viruses analysed at Centre were found to be antigenically and genetically similar to respective #WHO recommended #vaccine #strains for the S hemisphere in 2022. Of 3,372 samples tested for susceptibility to the #NAIs #oseltamivir & #zanamivir, 2 H1N1pdm09 viruses showed highly reduced inhibition against oseltamivir.''

#Efficacy of #favipiravir against #influenza virus #resistant to both #baloxavir and #NAIs, J Antimicrob Chemother., https://doi.org/10.1093/jac/dkad145

#Efficacy of #favipiravir against #influenza virus #resistant to both #baloxavir and #NAIs, J Antimicrob Chemother., https://doi.org/10.1093/jac/dkad145

#Efficacy of #favipiravir against #influenza virus #resistant to both #baloxavir and #NAIs, J Antimicrob Chemother., https://doi.org/10.1093/jac/dkad145

Attending the NAIS conference in Las Vegas?

Come visit HRP! We'll be on the floor in the nonprofit booth section and presenting our video game design session on Friday, February 24 - 1:15pm-2:15pm in room 202.

See you there! #restorehumanity #edchat ##nais

Attending the NAIS conference in Las Vegas?

Come visit HRP! We'll be on the floor in the nonprofit booth section and presenting our video game design session on Friday, February 24 - 1:15pm-2:15pm in room 202.

See you there! #restorehumanity #edchat ##nais

I'm wondering if there's a hashtag for #educators in #k12 #independentschool #privateschool settings. #NAIS
#edutooter

I'm wondering if there's a hashtag for #educators in #k12 #independentschool #privateschool settings. #NAIS
#edutooter

Hi #histodons: i'm a historian of the American West researching ties between Indigenous dispossession and US state formation in the 19th c. Interests in hgis and collaborative work that combines history and journalism. i teach at the university of cambridge. some tags of interest #americanhistory #nais #gis #ushistory #americanwest #digitalhistory #digitalhumanities

Hi #histodons: i'm a historian of the American West researching ties between Indigenous dispossession and US state formation in the 19th c. Interests in hgis and collaborative work that combines history and journalism. i teach at the university of cambridge. some tags of interest #americanhistory #nais #gis #ushistory #americanwest #digitalhistory #digitalhumanities