#mucosal — Public Fediverse posts

Broad #protection against #Influenza A Viruses via an adjuvant-free #mucosal microparticle #vaccine with conserved CD8/CD4 bispecific peptides, https://etidiohnew.blogspot.com/2026/04/broad-protection-against-influenza.html

Dual-Route #H5N1 #Vaccination Induces Systemic and #Mucosal #Immunity in Murine and Bovine Models, https://etidiohnew.blogspot.com/2025/09/dual-route-h5n1-vaccination-induces.html

Chapter One - #Mucosal #Sudan virus #infection results in a lethal disease in #ferrets with previous #Lloviu virus infection not providing cross-protection, https://etidiohnew.blogspot.com/2025/07/chapter-one-mucosal-sudan-virus.html

A trivalent #mucosal #vaccine encoding phylogenetically inferred ancestral #RBD #sequences confers pan- #Sarbecovirus #protection in mice https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(24)00403-7?rss=yes

Case et al. use ancestral phylogenetic reconstructions of Sarbecovirus sequences to generate a pan-Sarbecovirus vaccine. In mice, vaccine confers protection vs all tested Sarbecoviruses, including #SARS-CoV, multiple SARS-CoV-2 #variants, & pre-emergent Sarbecovirus strains.

#Intranasal M2SR (#M2-deficient Single Replication) #Influenza #Vaccine Induces Broadly Reactive #Mucosal #Antibody Production in Adults, J Infect Dis.: https://academic.oup.com/jid/advance-article-abstract/doi/10.1093/infdis/jiae361/7714804?redirectedFrom=fulltext&utm_source=advanceaccess&utm_campaign=jid&utm_medium=email

These data suggest that M2SR induces broadly cross-reactive mucosal immune responses which may provide better protection against drifted and newly emerging influenza strains.

#Intranasal M2SR (#M2-deficient Single Replication) #Influenza #Vaccine Induces Broadly Reactive #Mucosal #Antibody Production in Adults, J Infect Dis.: https://academic.oup.com/jid/advance-article-abstract/doi/10.1093/infdis/jiae361/7714804?redirectedFrom=fulltext&utm_source=advanceaccess&utm_campaign=jid&utm_medium=email

These data suggest that M2SR induces broadly cross-reactive mucosal immune responses which may provide better protection against drifted and newly emerging influenza strains.

#Intranasal M2SR (#M2-deficient Single Replication) #Influenza #Vaccine Induces Broadly Reactive #Mucosal #Antibody Production in Adults, J Infect Dis.: https://academic.oup.com/jid/advance-article-abstract/doi/10.1093/infdis/jiae361/7714804?redirectedFrom=fulltext&utm_source=advanceaccess&utm_campaign=jid&utm_medium=email

These data suggest that M2SR induces broadly cross-reactive mucosal immune responses which may provide better protection against drifted and newly emerging influenza strains.

#Intranasal M2SR (#M2-deficient Single Replication) #Influenza #Vaccine Induces Broadly Reactive #Mucosal #Antibody Production in Adults, J Infect Dis.: https://academic.oup.com/jid/advance-article-abstract/doi/10.1093/infdis/jiae361/7714804?redirectedFrom=fulltext&utm_source=advanceaccess&utm_campaign=jid&utm_medium=email

These data suggest that M2SR induces broadly cross-reactive mucosal immune responses which may provide better protection against drifted and newly emerging influenza strains.

#Intranasal M2SR (#M2-deficient Single Replication) #Influenza #Vaccine Induces Broadly Reactive #Mucosal #Antibody Production in Adults, J Infect Dis.: https://academic.oup.com/jid/advance-article-abstract/doi/10.1093/infdis/jiae361/7714804?redirectedFrom=fulltext&utm_source=advanceaccess&utm_campaign=jid&utm_medium=email

These data suggest that M2SR induces broadly cross-reactive mucosal immune responses which may provide better protection against drifted and newly emerging influenza strains.

Hier habe ich alle meine recherchierten Quellen zu #StreptococcusSalivarius #K12 gegen #Corona zusammengetragen:

https://pastebin.hot-chilli.net/?0b3ce182e423df09#4kFQvggKB9pudVE2bSCRXZ4sgHSuviMxvGAMcd75xw6b #Covid #SARSCoV2 #S_Salivarius #mucosal #Schleimhautimmunität

Hier habe ich alle meine recherchierten Quellen zu #StreptococcusSalivarius #K12 gegen #Corona zusammengetragen:

https://pastebin.hot-chilli.net/?0b3ce182e423df09#4kFQvggKB9pudVE2bSCRXZ4sgHSuviMxvGAMcd75xw6b #Covid #SARSCoV2 #S_Salivarius #mucosal #Schleimhautimmunität

Hier habe ich alle meine recherchierten Quellen zu #StreptococcusSalivarius #K12 gegen #Corona zusammengetragen:

https://pastebin.hot-chilli.net/?0b3ce182e423df09#4kFQvggKB9pudVE2bSCRXZ4sgHSuviMxvGAMcd75xw6b #Covid #SARSCoV2 #S_Salivarius #mucosal #Schleimhautimmunität

Hier habe ich alle meine recherchierten Quellen zu #StreptococcusSalivarius #K12 gegen #Corona zusammengetragen:

https://pastebin.hot-chilli.net/?0b3ce182e423df09#4kFQvggKB9pudVE2bSCRXZ4sgHSuviMxvGAMcd75xw6b #Covid #SARSCoV2 #S_Salivarius #mucosal #Schleimhautimmunität

Hier habe ich alle meine recherchierten Quellen zu #StreptococcusSalivarius #K12 gegen #Corona zusammengetragen:

https://pastebin.hot-chilli.net/?0b3ce182e423df09#4kFQvggKB9pudVE2bSCRXZ4sgHSuviMxvGAMcd75xw6b #Covid #SARSCoV2 #S_Salivarius #mucosal #Schleimhautimmunität

Respiratory #mucosal immune #memory to #SARS-CoV-2 after #infection and #vaccination, Nat Commun.: https://www.nature.com/articles/s41467-023-42433-w #research #vaccines #covid19 #immunity

#Mucosal and #Serum #Antibodies 3 Weeks after Symptomatic #BA286 #Infection, October 26, 2023, N Engl J Med 2023; 389:1626-1628,
DOI: 10.1056/NEJMc2310347 #covid19 #SARS_COV_2 #research #immunity

#Researchers have developed an #inhalable powder that could protect #lungs and airways from #viral invasion by reinforcing the body’s own #mucosal layer. The powder, called Spherical #Hydrogel Inhalation for Enhanced Lung Defense, or #SHIELD
#FLU #Covid19 #Virology #Biology #Engineering #Medical #sflorg
https://www.sflorg.com/2023/02/vi02092302.html

Rethinking #mucosal #vaccines against respiratory #viruses

"Because these viruses generally do not elicit complete and durable protective immunity by themselves, they have not to date been effectively controlled by licensed or experimental vaccines"

https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(22)00572-8

Very nice Clinical Pipeline by @cyrilpedia “#IntranasalVaccines COVID-19 #vaccine fails to induce #mucosal-immunity” at #Nature-Med doi: https://doi.org/10.1038/d41591-022-00106-z

#introduction I am an #immunologist at the #universityoftoronto. I study how our #mucosal immune system can influence our health, especially brain health. I love constructive discussions about science and how to make #academia a better place for everyone. I love #cooking, #gardening, #singing, #canoeing and learning from my 2 sons. Oh and my 3 @Cats too.