#microtubule — Public Fediverse posts

📰 "The Spectraplakin Short Stop (Shot) Organizes an Acentrosomal Microtubule Network in Early Oogenesis, Essential for Nuclear Positioning."
https://www.biorxiv.org/content/10.64898/2026.05.13.724832v1?rss=1 #Cytoskeletal #Microtubule #Forces

📰 "The Spectraplakin Short Stop (Shot) Organizes an Acentrosomal Microtubule Network in Early Oogenesis, Essential for Nuclear Positioning."
https://www.biorxiv.org/content/10.64898/2026.05.13.724832v1?rss=1 #Cytoskeletal #Microtubule #Forces

📰 "Beyond Redfield: Thermodynamic Bounds and Non-Perturbative Quantum Dynamics in Tubulin Networks"
https://www.biorxiv.org/content/10.64898/2026.05.10.724047v1?rss=1 #Microtubule #Dynamics

📰 "Beyond Redfield: Thermodynamic Bounds and Non-Perturbative Quantum Dynamics in Tubulin Networks"
https://www.biorxiv.org/content/10.64898/2026.05.10.724047v1?rss=1 #Microtubule #Dynamics

📰 "Emerin is necessary for microtubule-organizing center translocation to the nuclear envelope of muscle cells"
https://doi.org/doi:10.1038/s41419-026-08819-6
https://pubmed.ncbi.nlm.nih.gov/42120880/
#Microtubule #Dynamics

📰 "Emerin is necessary for microtubule-organizing center translocation to the nuclear envelope of muscle cells"
https://doi.org/doi:10.1038/s41419-026-08819-6
https://pubmed.ncbi.nlm.nih.gov/42120880/
#Microtubule #Dynamics

📰 "Nanotube topography inhibits NLRP3 inflammasome activation by reducing microtubule glutamylation"
https://doi.org/doi:10.1016/j.mtbio.2025.101838
https://pubmed.ncbi.nlm.nih.gov/40487178/
#Cytoskeletal #Microtubule #Mechanical

📰 "Liquid-Liquid Phase Separation-Mediated Cellular-Scale Compartmentalization of Hydrogel Covalent Cross-Linking Promotes Microtubule-Based Mechanosensing"
https://doi.org/doi:10.1021/jacs.5c00079
https://pubmed.ncbi.nlm.nih.gov/40252026/
#Mechanosensing #Extracellular #Microtubule #Mechanical

📰 "Microtubule-driven cell shape changes and actomyosin flow synergize to position the centrosome"
https://doi.org/doi:10.1083/jcb.202405126
https://pubmed.ncbi.nlm.nih.gov/40243666/
#Extracellular #Microtubule #Mechanical

@Rxiv_mechanobio

Interesting review !

"Far from being homogeneous beams, cytoskeletal filaments have complex mechanical properties, which are directly related to the specific structural arrangement of their subunits. They are also versatile, as the filaments’ mechanics and biochemistry are tightly coupled, and their
properties can vary with the cellular context."

#actin #microtubule #vimentin

A previous study in #plosbiology found that Wnt receptors are housed in early endosomes and required for dendritic #microtubule nucleation. This Update Article shows that microtubule dynamics in #dendrites can be influenced non-autonomously by surrounding epithelial cells plos.io/3DK0M0J

Arl2 regulates asymmetric division in fly neural stem cells via control of #microtubule growth. @HongyanWang9 &co show that, in mammalian #cortex, Arl2 binds to Cdk5rap2 to control microtubule growth, so regulating #corticogenesis #PLOSBiology https://plos.io/4dqDo5q

CFDP1 regulates cell proliferation & higher-order #chromatin structure. This study shows that CFDP1 is essential for structural stability of centromeric #heterochromatin, so influencing #microtubule nucleation during #MitoticSpindle formation #PLOSBiology https://plos.io/3W5eFhc

Please join us for MiQ talks on Wednesday 4th October 2023 at 15:00 UTC (8:00 PDT / 11:00 EDT / 16:00 BST / 17:00 CEST / 20:30 IST / 23:00 CST).

Speakers:

Alex Fellows (Carter lab) - MRC LMB Cambridge
Visualising endogenous dynein and its regulators reveal neuronal trafficking mechanisms

Shashi Thutupalli - NCBS Bangalore
Two-component molecular motor driven by a GTPase cycle

https://mechanochemistry.org/whatson/MiQ/index.php

#MotorHeads #Cytoskeleton #microtubule #microtubules

Are you interested in the #cytoskeleton ...?

#actin, #actomyosin, #myosin, #microtubule, #kinesin, #intermediatefilament, #vimentin, #keratin, #desmin, #GFAP, #peripherin, #syncoilin, #internexin, #neurofilament, #synemin, #syncoilin, #lamin

are hashtags used by @Rxiv_cytoskeleton bot.

Unfortunately, if you search / follow one of these hashtags, most of the posts from this bot will be invisible because a recent policy makes them "unlisted", see https://botsin.space/@muffinista/110378654504428500

#ScienceMastodon

1/2

Functionalization of #ribonucleoprotein #condensates with #microtubule motors provides new tools for re-directing RNA to centrosomes or the cell periphery

Audrey Cochard, Zoher Gueroui et al

https://www.embopress.org/doi/full/10.15252/embj.2023114106

#PLK1 and #PP2A-B56 form a bifunctional #kinase-#phosphatase module that balances mitotic #checkpoint strength and #kinetochore-#microtubule attachment dynamics

#RefereedPreprint c/o @ReviewCommons by Andrea Corno, Adrian Saurin et al

https://www.embopress.org/doi/full/10.15252/embj.2022112630

#PLK1 and #PP2A-B56 form a bifunctional #kinase-#phosphatase module that balances mitotic #checkpoint strength and #kinetochore-#microtubule attachment dynamics

#RefereedPreprint c/o @ReviewCommons by Andrea Corno, Adrian Saurin et al

https://www.embopress.org/doi/full/10.15252/embj.2022112630

#PLK1 and #PP2A-B56 form a bifunctional #kinase-#phosphatase module that balances mitotic #checkpoint strength and #kinetochore-#microtubule attachment dynamics

#RefereedPreprint c/o @ReviewCommons by Andrea Corno, Adrian Saurin et al

https://www.embopress.org/doi/full/10.15252/embj.2022112630

#PLK1 and #PP2A-B56 form a bifunctional #kinase-#phosphatase module that balances mitotic #checkpoint strength and #kinetochore-#microtubule attachment dynamics

#RefereedPreprint c/o @ReviewCommons by Andrea Corno, Adrian Saurin et al

https://www.embopress.org/doi/full/10.15252/embj.2022112630

#PLK1 and #PP2A-B56 form a bifunctional #kinase-#phosphatase module that balances mitotic #checkpoint strength and #kinetochore-#microtubule attachment dynamics

#RefereedPreprint c/o @ReviewCommons by Andrea Corno, Adrian Saurin et al

https://www.embopress.org/doi/full/10.15252/embj.2022112630

#Phosphorylation control in #mitosis:
Julie Welburn and colleagues reveal the molecular basis for #cellcycle regulation of #Kif4A and #CENPE motor interaction with #PRC1, needed to organize antiparallel #microtubule bundles and to ensure central spindle integrity, #midbody assembly and #cytokinesis

https://www.embopress.org/doi/full/10.15252/embj.2023113647

Release of cortical granules at #oocyte surface is critical for preventing #polyspermy. @ShamipourShayan @HeisenbergCPLab show that in #zebrafish this is driven by the concerted action of yolk granule fusion & #microtubule aster contraction #PLOSBiology https://plos.io/3oTs9hE

Why is a short loop in the extended #Ndc80 #kinetochore complex essential for #mitosis?
In vitro studies by Soumitra Polley @andreamusacchio @microtubule_guy @pim et al reveal its contribution to end-on #microtubule attachment via homotypic interactions between adjacent Ndc80 molecules
https://www.embopress.org/doi/10.15252/embj.2022112504

This one's phragmo...tastic?!
Du et al. describe a novel #microtubule and #actin filament #crosslinking protein that stabilizes the #phragmoplast during #cytokinesis.
https://doi.org/10.1111/jipb.13497
@wileyplantsci
#JIPB #PlantScience #cell #division #Arabidopsis

EMBO Journal Issue 4/23:
- Commentary on #creativity needs in research
- #Degron recognition in orphan complex subunits by CLR4-DCAF12 E3 #ubiquitin #ligase
- #Plasmamembrane topography of #IgM #Bcell receptors
- #YAP roles and regulation in #tumorigenesis
- #Brassinosteroid interplay with #katanin #microtubule severing

Cover by Satarupa Bhaduri, Analine Aguayo, Sonya Neal et al
https://www.embopress.org/toc/14602075/2023/42/4

Our latest work headed by former postdoc Aamir Ali finally out - we describe cooperation of XMAP215 family microtubule polymerase ch-TOG/CKAP5 with #gammaTuRC in promoting #microtubule #nucleation in human cells.
Details here: https://rdcu.be/c4cFp For a summary continue 1/n 👇🏼

How do #yeast adapt to #chromatinization with human #histones and subsequent #aneuploidy?

Jeff Boeke, @maxhaase et al from NYU Langone find #ploidy stabilization by DASH/Dam1 complex mutants that weaken #kinetochore-#microtubule attachment strength

https://www.embopress.org/doi/10.15252/embj.2022112600

#Invitro #reconstitution assays with purified brain #tubulin from mouse models lacking specific tubulin-modifying #enzymes show that tubulin #polyglutamylation patterns differentially regulate #microtubule-interacting protein binding

Carsten Janke, Marcus Braun and coworkers
https://www.embopress.org/doi/10.15252/embj.2022112101

#Brassinosteroid signals synergize with #katanin-mediated #microtubule severing to control #stamen filament elongation in #Arabidopsis

Zhaosheng Kong and coworkers

https://www.embopress.org/doi/10.15252/embj.2022111883

#Squid edit their RNA to keep cellular supply lines moving in the cold. Changing the genetic material may allow the #cephalopods to rapidly adjust to temperature swings https://www.sciencenews.org/article/squid-edit-rna-cold-adaptation

[#preprint] RNA recoding in cephalopods tailors #microtubule motor protein function https://www.biorxiv.org/content/10.1101/2022.09.25.509396v1

"In these #animals, 60 percent or more of their #proteins are actually recoded. This is astonishing in comparison to how rarely #RNAediting is used in #mammals"

Lovely #preprint from Minhajuddin Sirajuddin's team led by @mamata with awesome 😍 TIRF microscopy, in vitro reconstitution & #cryoEM, to illustrate how FAP20 recruits #tubulin to #microtubule lattice driving assembly of #cilia #MTDs, by joining the A- and B-tubules. https://www.biorxiv.org/content/10.1101/2022.11.25.517946v1

Throwback Thursday. #microscope #cellfie A mouse embryo fibroblast #MEF stained for #microtubule (blue) and #DNA (green). Images taken on a #Leica #confocal #SP8

My #introduction to #ScienceMastodon:
I am a #Cell #Biologist and research group leader at IRB Barcelona, Spain.
 In my lab we observe the #Microtubule #Cytoskeleton and try to make sense of what we see, what an awesome job!
We also like hashtags that start with C:
#Cell #Cytoskeleton #Centrosome #Centriole #Cilia
And we would like to know how to build a centrosome:

New bot! @Rxiv_cytoskeleton will toot all papers & preprints about the #cytoskeleton.
Namely, any match with "#actin, #actomyosin, #myosin, #microtubule, #kinesin, #intermediatefilament, #vimentin, #keratin, #desmin, #GFAP, #peripherin, #syncoilin, #internexin, #neurofilament, #synemin, #syncoilin, #lamin" in abstracts from #bioRxiv, #arXiv and #PubMed will be posted with #tags to tell you what's in there.
#biology #biophysics #science #ScienceMastodon #feed2toot @bioRxiv_biophys