#microed — Public Fediverse posts

Fisk University student Vida Robertson highlighted a publication from SBGrid member Tamir Gonen of University of California, Los Angeles that appeared in Advanced Science, in which the authors describe their use of MicroED to determine the conformational states of the commonly prescribed medication Mirabegron.

https://www.tumblr.com/sbgridconsortium/732639903900368896/using-microed-for-molecule-conformations?source=share

<ALT= Dog beta3 adrenergic receptor (grey) and Mirabegron (cyan)>

#sbgrid
#structuralbiology
#research
#MicroEd
#science

Fantastic to see #cryoEM #MicroED having an impact on problems that have otherwise resisted investigation by #crystallography in this new pre-print from Cody Gillman in Tamir Gonen's lab at UCLA. With the help of molecular docking simulations suggest a mechanism of action where a non-proteinaceous toxin adopts a peptide-reminiscent hairpin structure to block the channel.
https://www.biorxiv.org/content/10.1101/2023.03.31.53516

Excited to be presenting a Thermo Fisher Scientific Ask the Experts webinar 3/22/23 11am EDT with Devrim Acehan!

We'll discuss emerging methods in cryo-EM of microcrystals, as well as our collaborative work as we seek to further develop microcrystal detection and handling methods.

Register here: https://tinyurl.com/2p9d9zer

www.getacrystal.org
www.cryo-EM.center

#structuralbiology #crystallization #cryoem #microED #webinar
@strucbio

Hi from the National High-Throughput Crystallization (HTX) Center in #Buffalo NY.

The HTX Center specializes in #crystallization 💎 for #StructuralBiology.

We are a team of 👩🏻‍🔬👩🏼‍🔬 👩🏽‍🔬 👩🏾‍🔬 and will often post #crystal images, #robot images, and updates for HTX Center users.

www.getacrystal.org

#introduction #toot

#Crystallography #XrayCrystallography #NeutronCrystallography #XFEL #microED

Hi all - new to #Mastodon (fleeing the 🦃 #TwitterMigration).

I'm an Associate Investigator & #StructuralBiologist at HWI in Buffalo #NY. I direct the National High-Throughput #Crystallization Center 💎.

My group uses X-ray #crystallography, #microED, #computationalbiology, & other #biophysical tools to study #protein structure & function.

Especially interested in #metalloproteins & coupling #crystallography & #spectroscopy.

#Introduction #Science #SciComm #structuralbiology #WomeninSTEM

Hi all - new to #Mastodon (fleeing the 🦃 #TwitterMigration).

I'm an Associate Investigator & #StructuralBiologist at HWI in Buffalo #NY. I direct the National High-Throughput #Crystallization Center 💎.

My group uses X-ray #crystallography, #microED, #computationalbiology, & other #biophysical tools to study #protein structure & function.

Especially interested in #metalloproteins & coupling #crystallography & #spectroscopy.

#Introduction #Science #SciComm #structuralbiology #WomeninSTEM

Hi all - new to #Mastodon (fleeing the 🦃 #TwitterMigration).

I'm an Associate Investigator & #StructuralBiologist at HWI in Buffalo #NY. I direct the National High-Throughput #Crystallization Center 💎.

My group uses X-ray #crystallography, #microED, #computationalbiology, & other #biophysical tools to study #protein structure & function.

Especially interested in #metalloproteins & coupling #crystallography & #spectroscopy.

#Introduction #Science #SciComm #structuralbiology #WomeninSTEM

Hi all - new to #Mastodon (fleeing the 🦃 #TwitterMigration).

I'm an Associate Investigator & #StructuralBiologist at HWI in Buffalo #NY. I direct the National High-Throughput #Crystallization Center 💎.

My group uses X-ray #crystallography, #microED, #computationalbiology, & other #biophysical tools to study #protein structure & function.

Especially interested in #metalloproteins & coupling #crystallography & #spectroscopy.

#Introduction #Science #SciComm #structuralbiology #WomeninSTEM

Hi all - new to #Mastodon (fleeing the 🦃 #TwitterMigration).

I'm an Associate Investigator & #StructuralBiologist at HWI in Buffalo #NY. I direct the National High-Throughput #Crystallization Center 💎.

My group uses X-ray #crystallography, #microED, #computationalbiology, & other #biophysical tools to study #protein structure & function.

Especially interested in #metalloproteins & coupling #crystallography & #spectroscopy.

#Introduction #Science #SciComm #structuralbiology #WomeninSTEM