#mdmaassistedtherapy — Public Fediverse posts

https://pubmed.ncbi.nlm.nih.gov/39741438/ MDMA and MDMA-Assisted Therapy (Wolfgang, et al, 2025) #mdma #psychedelic #psychedelics #mdmaassistedtherapy #psychedelicresearch

https://pubmed.ncbi.nlm.nih.gov/39531488/ Cost-effectiveness of midomafetamine-assisted therapy (MDMA-AT) in chronic and treatment-resistant post-traumatic stress disorder of moderate or higher severity: A health-economic model (Stanicic, et al, 2024) #mdma #mdmaassistedtherapy #mdmaassistedpsychotherapy #psychedelic #psychedelics #mentalhealth #psychedelicmentalhealth

What #psychedelics are available for #psychedelicassistedpsychotherapy now that the #fda rejected one company's application for #mdmaassistedtherapy for #ptsd? Generic, racemic #ketamine with many other molecules in various FDA-approved phases of development for many #mentalhealth indications. For use in collaboration with your medical and mental health care providers. https://psychedelicmentalhealth.net/what-medicines-are-available-for-psychedelic-assisted-psychotherapy/

With FDA decision looming, bipartisan group of lawmakers urge support for MDMA to treat PTSD https://www.cnn.com/2024/08/05/politics/congress-members-biden-fda-mdma-therapy-veterans/index.html #mdma #fda #psychedelics #psychedelic #ptsd #mdmaassistedtherapy

https://www.scientiststatementonptsd.com/ Experts Endorse MDMA-assisted Therapy for PTSD

Re: Lykos Therapeutics NDA #215455, Midomafetamine (MDMA) for use in the treatment of PTSD #mdma #psychedelic #psychotherapy #psychedelics #ptsd #tdsuma #mentalhealth #psychedelicresearch #mdmaassistedtherapy #mdmaassistedpsychotherapy #psychedelicassistedpsychotherapy #neuroscience #psychiatry #cognitivebehavioraltherapy #fda

MAPS, MDMA, and Beyond- Livestreaming TODAY at 4pm PST - https://www.youtube.com/watch?v=sDfLfgaZWss #psychedelic #psychedelics #psychedelicresearch #mdma #mdmaassistedtherapy #psychedelictherapy #psychedelicassistedpsychotherapy

https://pubmed.ncbi.nlm.nih.gov/38401800/ Recreational MDMA doses do not elicit hepatotoxicity in HepG2 spheroids under normo- and hyperthermia (de Oliveira, et al, 2024) #mdma #fda #psychedelic #psychedelics #psychedelicresearch #fda #studydesign #litreview #ptsd #psychedelicassistedtherapy #mdmaassistedtherapy #entactogens #neuroscience

https://pubmed.ncbi.nlm.nih.gov/38743292/ The entactogen 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) as a treatment aid in psychotherapy and its safety concerns (Baldo, et al, 2024) #mdma #fda #entactogens #psychedelic #psychedelics #psychedelicresearch #psychedelicassistedpsychotherapy #mdmaassistedtherapy Note: FDA has approved trials of MDMA for: #ptsd #socialanxiety (especially related to #autism) #alcoholusedisorder #eatingdisorders #asociality related to #schizophrenia #deathanxiety

https://pubmed.ncbi.nlm.nih.gov/38896930/ The efficacy and safety of MDMA-assisted psychotherapy for treatment of posttraumatic stress disorder: A systematic review and meta-analysis from randomized controlled trials (Yang, et al, 2024) #mdma #fda #psychedelic #psychedelics #fda #psychedelicresearch #MDMAtherapy #mdmaassistedtherapy #ptsd #psychedelictherapy #psychedelicassistedpsychotherapy #neuroscience #psychiatry #mentalhealth — Adverse effects found not to interfere with efficacy

https://pubmed.ncbi.nlm.nih.gov/38957734/ Hepatic injury and hepatic failure adverse events in 3,4-methylenedioxymethamphetamine users reported to the FDA Adverse Event Reporting System (Makunts, et al, 2024) #mdma #dili #liver #psychedelic #psychedelicresearch #faers #fda #psychedelics #mdmaassistedtherapy — finding in estimated 20 million, perhaps 1 case of liver damage from MDMA, increased risk with poly drug use.

https://onlinelibrary.wiley.com/doi/10.1111/jnc.16149 Bioisosteric analogs of MDMA: Improving the pharmacological profile? (Alberto-Silva, et al, 2024) #mdma #mdmaassistedtherapy #psychedelics #psychedelic #psychedelicresearch #psychedelicassistedpsychotherapy

https://psychedelic-institute-of-mental-health.ghost.io/does-the-psychedelic-experience-matter/ still working on this one, but it’s coming together — #psychedelics #psychedelic #ketamine #fda #mdma #mdmaassistedpsychotherapy #mdmaassistedtherapy #ketamine #Ketamineassistedtherapy #ketamineassistedpsychotherapy #psychedelic #psychedelics #psychedelictherapy #psychedelicassistedpsychotherapy #nde #mysticalexperience #therapycult #phenomenology #consciousness #neuroscience #studydesign #psychedelicresearch #psychotherapy #lsd #dmt #psilocybin #psilocin #ayahausca

https://clinicaltrials.gov/study/NCT05746572?term=mdma%20ptsd%20and%20emory&rank=1&a=8 Emory University plans #fda Phase 2 study of #mdma plus a type of behavioral #psychotherapy called Exposure Therapy for the treatment of #ptsd — This study is unrelated to the MAPS/Lykos new drug application for #mdmaassistedtherapy and a reminder #psychedelic #research is robust and ongoing. #studydesign should include blinding with #ketamine and comparison to #cognitivebehavioraltherapy #psychedelics

https://youtu.be/DiHeBbOs-AU #mdma #psychedelics #Psilocybin #cannabis #lsd #ketamine #mdmaassistedtherapy #fda #ketamineassistedpsychotherapy #psychedelicassistedpsychotherapy #grief #deathanxiety #existentialdread #psychedelic #psychedelics #psychedelictherapy #psychedelicresearch The fact that people have measurable changes in thoughts, feelings, emotions, behaviors and MEANING after psychedelic therapy when supported by another human is measurable, even if obvious. #dosed #palliativecare #hospice

https://www.sciencedirect.com/science/article/abs/pii/S0165178123005358?via%3Dihub Cognitive behavioral therapy following esketamine for major #depression and suicidal ideation for relapse prevention: The CBT-ENDURE randomized clinical trial study protocol (Kitay, et al, 2023) proposes pilot #studydesign with #fda approved #ketamine formulation with #cognitivebehavioraltherapy #psychedelics #psychedelicresearch #mdma #mdmaassistedtherapy #ketaminetherapy #ketamineassistedpsychotherapy

https://www.psychologytoday.com/intl/blog/the-psychedelic-therapy-doctor/202406/ketamine-today-mdma-tomorrow #ketamine #mdma #fda #ketamineassistedpsychotherapy #psychedelicassistedpsychotherapy #mdmaassistedtherapy #ptsd #psychedelicresearch #studydesign Blind with ketamine, and offer with and without the gold standard of cognitive behavioral therapy

@jeztastic cite your sources. I’ve cited mine. If you want to do a multi-year, full-time lit review on how cbt is not effective, and is not evidence-based, feel free. It has been studied, with and without psych meds and psychedelics, and offers better study design than whatever Lykos presented for #mdmaassistedtherapy

The effect of acutely administered MDMA on subjective and BOLD-fMRI responses to favourite and worst autobiographical memories (Carhart-Harris, et al, 2014) https://academic.oup.com/ijnp/article/17/4/527/644594#11036186 in which they discuss #mdma as assisting #psychotherapy #psychedelicassistedpsychotherapy #mdmaassistedtherapy #ketamine #psychedelics #psychedelicresearch #psychedelic

https://onlinelibrary.wiley.com/doi/10.1002/ccr3.8791 Long-COVID symptoms improved after MDMA and psilocybin therapy: A case report (Chopra, et al, 2024) #LongCovid #covid #mdma #psilocybin #ketamine #psychedelictherapy #psychedelicassistedpsychotherapy #mdmaassistedtherapy #fda #covidsymptomsimproved

https://youtu.be/PJtTF5aMPbU #mdma #mdmaassistedtherapy #psychedelictherapy #psychedelictraining #psilocybin #Psychedelics #psychedelicresearch #ptsd #ketamine #ketamineassistedpsychotherapy #psychedelictherapist #fda #psyhedelicassistedpsychotherapy “therapists are key” “it’s about human connection” - training therapists is "most exciting development".

One member of the FDA advisory committee, and non-voting, industry rep worked on Spravato for Jansen. Her colleague, a psychiatrist was MAPS-trained and works with ketamine currently. Let’s talk conflict of interests. What #psychiatricmedicines have been tested against the gold standard of cognitive behavioral therapy? Which of the providers in the #mdmaassistedtherapy trials or advisory meeting actually practice CBT? #studydesign #litreview #contactus

https://pubmed.ncbi.nlm.nih.gov/38773523/ Effect of MDMA-assisted therapy on mood and anxiety symptoms in advanced-stage cancer (EMMAC): study protocol for a double-blind, randomised controlled trial
(Bhagavan et al. Trials. 2024) Note: Scientific clinical trials are not the same as mental health treatment. #mdma #mdmaassistedtherapy #newzealand #deathanxiety #depression #oncology #anxiety #depression #psychedelic #psychedelicresearch #oncology #psychedelicassistedpsychotherapy

If you are interested, here are some of the public critiques:

https://youtu.be/PSqotSD6WOg

And here is the whole session:

https://www.youtube.com/live/JqQKP8gcY1E

#mdmaassistedtherapy #mdma #fdaadvisorypanel #fda

If you are interested, here are some of the public critiques:

https://youtu.be/PSqotSD6WOg

And here is the whole session:

https://www.youtube.com/live/JqQKP8gcY1E

#mdmaassistedtherapy #mdma #fdaadvisorypanel #fda

(#wapo #GiftLink below)

I am a big supporter of psychedelic based therapies, including #MDMA. I think MDMA will be a component of future PTSD treatment.

Yet, I'm VERY happy with the advisory board's decision to say no. The company, Lykos Therapeutics, simply can't be trusted in this space. I would encourage the #FDA to follow the advice of the committee.

#psychedelics #psychedelicmedicine #ptsd #ptsdhealth #mdmaassistedtherapy

https://wapo.st/4ea3pqj

(#wapo #GiftLink below)

I am a big supporter of psychedelic based therapies, including #MDMA. I think MDMA will be a component of future PTSD treatment.

Yet, I'm VERY happy with the advisory board's decision to say no. The company, Lykos Therapeutics, simply can't be trusted in this space. I would encourage the #FDA to follow the advice of the committee.

#psychedelics #psychedelicmedicine #ptsd #ptsdhealth #mdmaassistedtherapy

https://wapo.st/4ea3pqj

The early use of MDMA (‘Ecstasy’) in psychotherapy (1977–1985) (Passie, et al, 2018)
https://journals.sagepub.com/doi/full/10.1177/2050324518767442 #mdma #psychotherapy #fda #mdmaassistedtherapy #psychedelics #psychedelicresearch #psychedelicassistedpsychotherapy