#lupusresearch — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #lupusresearch, aggregated by home.social.
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After a looong journey, I can present you the results of a deep & thorough investigation of human plasma proteolysis by mass spec: SLE N-terminomics paper with a complement C3 fragment(s) is out now in EMBOJ: https://www.embopress.org/doi/full/10.1038/s44318-025-00598-8 - highlights: a nice resource on proteolytically processed N-termini in human plasma of healthy & SLE patients, with a lot of complement bonus for all interested scientists. #SLE #Science #Proteomics #TeamMassSpec #InflammatoryDisease #LupusResearch #C3 #LHF1 1/10
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Der Mann hat was neues für #Lupus gefunden - oder wie @kabalak selbst sagen würde:
In conclusion, this study uncovers a new dimension of immune crosstalk: a proteolytic plasma network that generates immunoactive fragments with intrinsic self-regulatory capabilities to modulate #inflammation and tissue injury in complex disease contexts. Deciphering these immunoactivities may pave the way for innovative diagnostic and therapeutic strategies in complement-driven pathologies, potentially benefiting a wide range of inflammatory and autoimmune diseases.
#AutoimmuneDiseases #InflammatoryDisease #Science #SLE #proteomics #MassSpec #TeamMassSpec #LupusResearch
https://www.embopress.org/doi/full/10.1038/s44318-025-00598-8
