#llps — Public Fediverse posts

Please share …. 🙏
📣 Very soon, we’ll have an open PhD position starting in fall 2025 — this time not on cilia, but on YAP & TAZ in podocytes and their regulation via LLPS. Interested candidates are welcome to contact us directly.

Supervision by Inês Cabrita and me, embedded within PodoSigN!
Within this project, close collab. with Beate Vollenbröker‘s team.

#Podocyte #Trr422 #Fsgs #Nephrolab #PhdPosition #Biology #Genetics #LLPS #HippoSignaling #phd

@CECAD
@cilia

Liprin-α & RIM form presynaptic liquid phase-separated condensates #LLPS. This Primer explores a @PLOSBiology study of how these assemblies shape #synaptic fidelity and what their disruption might mean in #neurodevelopmental disease. Paper: https://plos.io/3Tj5CX7 Primer: https://plos.io/3HTacJ9

#Cellular structure without a #membrane: Researcher discusses how #synapses use #liquids to create functional separations.

#LLPS #membrane-less_organelles #neurotransmission

https://phys.org/news/2025-03-cellular-membrane-discusses-synapses-liquids.html

This allows condensate behaviour to respond to different inputs, such as lysine #acetylation in IDRs in other CBP domains. It can help to explain how #transcription factors binding to different regions of CBP differentially regulate CBP activity. #enhancers #generegulation #llps #chromatin #imaging #biochemistry #molecularbiology #CellBiology

In developing #presynapses, the #ActiveZone structure assembles via liquid-liquid #PhaseSeparation (#LLPS). This study shows that the #kinase SAD-1 phosphorylates the scaffold protein SYD-2/Liprin-α, relieving autoinhibition & triggering LLPS #PLOSBiology https://plos.io/3Ne6OZg