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#linkagedisequilibrium — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #linkagedisequilibrium, aggregated by home.social.

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  1. ‘Vertical’ #pleiotropy is when a variant affects a phenotype that has its own downstream effects on another phenotype

    ‘Horizontal’ pleiotropy is where a variant has multiple independent effects; no phenotype mediates another

    Needless terminology! Easily represented in simple #DAGs as chaining and common cause, respectively. #Genetics should avoid making up new terms for simple stuff.

    The interesting twist for genetics is #LinkageDisequilibrium because it can masquerade as pleiotropy

  2. ‘Vertical’ is when a variant affects a phenotype that has its own downstream effects on another phenotype

    ‘Horizontal’ pleiotropy is where a variant has multiple independent effects; no phenotype mediates another

    Needless terminology! Easily represented in simple as chaining and common cause, respectively. should avoid making up new terms for simple stuff.

    The interesting twist for genetics is because it can masquerade as pleiotropy

  3. ‘Vertical’ #pleiotropy is when a variant affects a phenotype that has its own downstream effects on another phenotype

    ‘Horizontal’ pleiotropy is where a variant has multiple independent effects; no phenotype mediates another

    Needless terminology! Easily represented in simple #DAGs as chaining and common cause, respectively. #Genetics should avoid making up new terms for simple stuff.

    The interesting twist for genetics is #LinkageDisequilibrium because it can masquerade as pleiotropy

  4. ‘Vertical’ #pleiotropy is when a variant affects a phenotype that has its own downstream effects on another phenotype

    ‘Horizontal’ pleiotropy is where a variant has multiple independent effects; no phenotype mediates another

    Needless terminology! Easily represented in simple #DAGs as chaining and common cause, respectively. #Genetics should avoid making up new terms for simple stuff.

    The interesting twist for genetics is #LinkageDisequilibrium because it can masquerade as pleiotropy