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#laminb — Public Fediverse posts

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  1. #ER - #membrane contact sites are often distorted by existing labeling methods. @steveroyle &co present an inducible labeling system (LaBeRling) using #LaminB receptor to fluorescently tag ER-membrane contact sites in live cells, preserving morphology @PLOSBiology plos.io/4lv6gxu

  2. #ER - #membrane contact sites are often distorted by existing labeling methods. @steveroyle &co present an inducible labeling system (LaBeRling) using #LaminB receptor to fluorescently tag ER-membrane contact sites in live cells, preserving morphology @PLOSBiology plos.io/4lv6gxu

  3. new research article:
    Nuclear lamina erosion-induced resurrection of endogenous retroviruses underlies neuronal aging

    doi.org/10.1016/j.celrep.2023.

    "we verified the loss of B-type lamins inducing resurrection of ERVs as an initiating event of the aging-bound cascade in post-mitotic neurons. Of significance, these aging-related cellular and molecular changes can be alleviated by abacavir"

    #Brain #Aging #HERV #EndogenousRetrovirus
    #laminB #DrugRepurposing