🧬🌟 How do cells assemble complex machinery at the right place and time? A new study in Nature Cell Biology reveals the role of local concentration in triggering the formation of kinetochores, the structures that sort and transport chromosomes during cell division. #cells #kinetochores #concentration https://phys.org/news/2024-01-cells-accurately-complex-machinery.html
#kinetochores — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #kinetochores, aggregated by home.social.
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A #CRISPR-Cas9-tagging approach to induce #chromosome-specific segmental #aneuploidies: targeted assembly of ectopic #kinetochores at endogenous repeats - a way to recapitulate and study specific disease-associated #missegregation events in human cells
@McClellandLab
https://www.embopress.org/doi/10.15252/embj.2022111587 -
#Parasitology paperwatch: recent review from Midori Ishii & Bungo Akiyoshi on #centromeres and #kinetochores. Principally describes the distinction between monocentric and holocentric centromeres, the role of the histone H3 variant CENP-A (when present) and their taxonomic distribution. It then touches on #kinetoplastid kinetochores and the riddle of what defines their centromeres at the end. 😀 👍 👏
https://www.sciencedirect.com/science/article/pii/S0955067422000011