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#kinetochore — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #kinetochore, aggregated by home.social.

  1. #RZZ-#Spindly complex and #CENPE (#kinesin-7) are intimately connected and reciprocally required for their own #kinetochore recruitment, #dynein/#dynactin localization, and expansion of the kinetochore fibrous corona

    Verena Cmentowski @andreamusacchio et al

    embopress.org/doi/full/10.1525

  2. Sophie Dumont at UCSF
    dumontlab.ucsf.edu/

    #Chromosome size alters #kinetochore attachment stability and alignment order in mammalian #mitosis

    Lab interested in #SelfOrganization and emergent mechanics across scales.... "biological structures build themselves" using only local cues they get global information. mitotic spindle a great example

    kinetochores attach, sense tension, can make mistakes which are corrected. how does this work when chromosomes vary in size?

    #CSSingleCells23

    1/2

  3. How do #yeast adapt to #chromatinization with human #histones and subsequent #aneuploidy?

    Jeff Boeke, @maxhaase et al from NYU Langone find #ploidy stabilization by DASH/Dam1 complex mutants that weaken #kinetochore-#microtubule attachment strength

    embopress.org/doi/10.15252/emb