#kinetochore — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #kinetochore, aggregated by home.social.
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Sophie Dumont at UCSF
http://www.dumontlab.ucsf.edu/#Chromosome size alters #kinetochore attachment stability and alignment order in mammalian #mitosis
Lab interested in #SelfOrganization and emergent mechanics across scales.... "biological structures build themselves" using only local cues they get global information. mitotic spindle a great example
kinetochores attach, sense tension, can make mistakes which are corrected. how does this work when chromosomes vary in size?
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How do #yeast adapt to #chromatinization with human #histones and subsequent #aneuploidy?
Jeff Boeke, @maxhaase et al from NYU Langone find #ploidy stabilization by DASH/Dam1 complex mutants that weaken #kinetochore-#microtubule attachment strength