#kinetics — Public Fediverse posts

💁🏻‍♀️ ICYMI: 🪵🎵 Japanese artist Ayumi Tsuchiya creates interactive wooden #sculptures that function as playground #toys, musical #instruments, and hands-on #engineering lessons.

Using #gravity, #gears, balance, and #timber, her analog #designs invite people to touch, move, and listen without relying on screens or #software.

👉 Learn more: https://seethis.tv/post/musical-gear-wonderlands-interactive-wooden-sculptures-by-ayumi-tsuchiya

#art #chair #installation #japan #kids #kinetics #levers #machines #mechanics #music #physics #play #science #songs #sound #womeninstem #wood #tksst #video

💁🏻‍♀️ ICYMI: 🪵🎵 Japanese artist Ayumi Tsuchiya creates interactive wooden #sculptures that function as playground #toys, musical #instruments, and hands-on #engineering lessons.

Using #gravity, #gears, balance, and #timber, her analog #designs invite people to touch, move, and listen without relying on screens or #software.

👉 Learn more: https://seethis.tv/post/musical-gear-wonderlands-interactive-wooden-sculptures-by-ayumi-tsuchiya

#art #chair #installation #japan #kids #kinetics #levers #machines #mechanics #music #physics #play #science #songs #sound #womeninstem #wood #tksst #video

💁🏻‍♀️ ICYMI: 🪵🎵 Japanese artist Ayumi Tsuchiya creates interactive wooden #sculptures that function as playground #toys, musical #instruments, and hands-on #engineering lessons.

Using #gravity, #gears, balance, and #timber, her analog #designs invite people to touch, move, and listen without relying on screens or #software.

👉 Learn more: https://seethis.tv/post/musical-gear-wonderlands-interactive-wooden-sculptures-by-ayumi-tsuchiya

#art #chair #installation #japan #kids #kinetics #levers #machines #mechanics #music #physics #play #science #songs #sound #womeninstem #wood #tksst #video

💁🏻‍♀️ NEW: 🪵🎵 Japanese artist Ayumi Tsuchiya creates interactive wooden #sculptures that function as playground #toys, musical #instruments, and hands-on #engineering lessons.

Using #gravity, #gears, balance, and #timber, her analog #designs invite people to touch, move, and listen without relying on screens or #software.

👉 Learn more: https://seethis.tv/post/musical-gear-wonderlands-interactive-wooden-sculptures-by-ayumi-tsuchiya

#art #chair #installation #japan #kids #kinetics #levers #machines #mechanics #music #physics #play #science #songs #sound #womeninstem #wood #tksst #video

The last couple of weeks, I was busy preparing for the #CCPEM Spring Symposium and then attending it and presenting at it. So I am only finding time now to share a new preprint that went online earlier this month: https://doi.org/10.64898/2026.04.02.716132

It is about the regulation of CsoSCA, the carbonic anhydrase (CA) found in alpha-carboxysomes. Through a combination of stopped-flow #kinetics, #bioinformatics and #cryoEM, we showed that this enzyme is sensitive to redox conditions. This likely keeps it inactive in the reducing cytosol, where CA activity would short-circuit the CO2 concentration mechanism by turning cytosolic bicarbonate into CO2, which can diffuse through membranes. This redox sensitivity also activates CsoSCA inside mature carboxysomes, because their interior becomes oxidizing as their shell excludes cytosolic reductants.
Overall, CsoSCA's redox sensitivity conditions its activation to its correct encapsulation in carboxysomes.

Turns out visualizing a regulatory disulfide by #cryoEM is difficult! In this case, the strongest evidence for it comes from activity measurements and site-directed mutagenesis. But the structures revealed a conformational equilibrium that we would not have suspected, had we not attempted to solve structures of the enzyme in the active and inactive conditions.

This was excellent team work with first author Nikole and all others, with a real cross-talk between the biochemistry and structures!

Modeling of #H5N1 #influenza virus #kinetics during dairy #cattle #infection suggests the timing of infectiousness, https://etidiohnew.blogspot.com/2026/01/modeling-of-h5n1-influenza-virus.html

@FotoVorschlag
'Im (Bastel) Keller ' #FotoVorschlag

Nicht mein Bastelkeller, sondern die Werkstatt eines fabelhaften, genialen #Brompton Künstlers, des wunderbaren #BenCooper von #Kinetics in #Glasgow

So sah es 2016 bei meinem Besuch aus. Inzwischen hat er die Werkstatt nebenan dazu bekommen und etwas mehr Platz.

#LabPlot at the service of #researchers. :boost_love:

@[email protected]

It's rewarding to us to know that #LabPlot was used for the #drug release #kinetics investigation in this recent study on niosomal co-delivery of #metformin and #telaglenastat.

➡️ https://www.sciencedirect.com/science/article/pii/S0753332225010376

#Research #Science #OpenSource #FreeSoftware #FOSS #KDE #FreeOriginProAlternative #BreastCancer #Cancer #Cytotoxicity

@margraf
also #FediHire and #fedijobs and #Job and #Jobs
I would also recommend some hashtags related tobthe subject. #maschinelearning and #chemistry and #kinetics would be good subject appropiate ones.

I replaced vector databases with Git for AI memory (PoC)

https://github.com/Growth-Kinetics/DiffMem

#HackerNews #AI #Memory #Git #Vector #Databases #PoC #Growth #Kinetics

Interesting paper by the group of Peter Tonge in JACS. They studied the detailed kinetics of non-covalent BTK inhibitors. Interesting insights that clinical compounds showed increased residence times, while association rates remained nearly constant. https://pubs.acs.org/doi/10.1021/jacs.5c07063
#Kinases #DrugDiscovery #Chemistry #ChemBio #BTK #Kinetics

@velospinner: They're are exaggerating claiming "We made". Actually the #MTBrompton is "Ben Cooper made", they just assembled the kit (but yeah, they mention it, but then again, they don't link to his site): https://www.kinetics-online.co.uk/folding-bikes/brompton/the-mtbrompton/

But yeah, that's a great and hilarious #GCN episode.

You might also enjoy this #BermPeak episode where Seth of Berm Peak takes a standard #Brompton C-Line to a #skatepark 🤪: https://www.youtube.com/watch?v=TLg0NNjDBMQ

Spoiler: It survives. 😉

#BenCooper #Kinetics

Characterising viral #clearance #kinetics in acute #influenza, https://etidiohnew.blogspot.com/2025/03/characterising-viral-clearance-kinetics.html

Viral #kinetics of #H5N1 #infections in dairy #cattle, https://etidiohnew.blogspot.com/2025/02/viral-kinetics-of-h5n1-infections-in.html

#Replication #Kinetics, #Pathogenicity and Virus-induced Cellular Responses of #Cattle-origin #Influenza A(#H5N1) Isolates from #Texas, United States

Source: BioRxIV, AbstractThe host range of HPAIV H5N1 was recently expanded to include ruminants, particularly dairy cattle in the United States. Shortly after, human H5N1 infection was reported in a dairy worker in Texas following exposure to infected cattle. Herein, we rescued the cattle-origin influenza…

https://etidioh.wordpress.com/2024/10/30/replication-kinetics-pathogenicity-and-virus-induced-cellular-responses-of-cattle-origin-influenza-ah5n1-isolates-from-texas-united-states/

#BenCooper aka #Kinetics posted a comparison table between his 20" #MTBrompton conversion and the new ex-works 20" #Brompton #G_Line: https://www.kinetics-online.co.uk/technical-info/g-line-vs-mtbrompton/

@insl: It's now on his website at https://www.kinetics-online.co.uk/custom-builds/recumbent-brompton/ and official: #BenCooper aka #Kinetics plans to offer a #Brompton FWD #recumbent kit in the future!

Citing from there:

"This, with some more development, will be a kit that you can add to your own Brompton – there’s no modification needed to the mainframe, it just replaces the front fork. Watch this space…"

There's even a video of unfolding it!

This solves at least the "problem" what to do with my current Brompton if I buy a G-Line. 😉

#Morphology-dependent #entry #kinetics and #spread of #influenza A virus, BioRxIV: https://www.biorxiv.org/content/10.1101/2024.08.01.605992v1

We found that cellular junction integrity and mucin do not exert morphology-dependent inhibition of IAV cell-to-cell spread. On the other hand, filamentous #virions confer an advantage under the #pressure exerted by neutralizing #antibodies against #hemagglutinin.

#Assessment of #Survival #Kinetics for Emergent Highly Pathogenic Clade 2.3.4.4 #H5Nx Avian #Influenza #Viruses, Viruses: https://www.mdpi.com/1999-4915/16/6/889

Statistical tests of the difference between the DT values and extinction times of each clade 2.3.4.4 strain at each #temperature indicated that the majority displayed different survival kinetics from the other strains at 4 °C and 20 °C.

The #kinetics and optimality of #influenza A virus #locomotion http://biorxiv.org/cgi/content/short/2024.05.06.592729v1?rss=1

Our findings suggest novel therapeutic targets and provide insight into possible mechanisms of #zoonotic #transmission.

"Here, using operando optical microscopy, we image the local doping level of the #transistor channel and show that turn-on occurs in two stages—propagation of a doping front, followed by uniform doping—while turn-off occurs in one stage. We attribute the faster turn-off to a combination of engineering as well as physical and chemical factors including channel geometry, differences in doping and dedoping #kinetics and the phenomena of carrier-density-dependent mobility"

https://www.nature.com/articles/s41563-024-01875-3

#DogWalkingGeology from this morning. Here's a lovely wee layer of pale blue elongate kyanite crystals, pale pink elongate andalusite, plus some wee brown round garnets, in schist from Ardalanish Bay. Although the andalusite and kyanite look happy together, they are not actually in equilibrium: this layer has "frozen" during the slow process of converting kyanite to andalusite. Reactions are all about the kinetics! #Metastable #Mull #Moine #RossOfMullGranite #Geology #Minerals #Al2SiO5 #Kinetics

Long term anti- #SARS-CoV-2 #antibody #kinetics and correlate of #protection against #Omicron BA.1/ #BA2 infection https://www.nature.com/articles/s41467-023-38744-7

Applications session: Talk

6. Ulrike Wittig introduces the SABIO-RK Database, a manually curated database for biochemical reactions and their kinetics, and explains about improved insights via visualization of data

#biocuration2023 #Applications #biochemicalreactions #kinetics