#jgshare — Public Fediverse posts

Autism genetics: “mice with a single mutated CHD8 copy (heterozygous) expressed behavioral abnormalities strictly in males, the severe double-mutated homozygous models displayed devastating autism traits in both males and females.”

https://neurosciencenews.com/chd8-mutation-asd-genetics-30734/

Studying 4:1 ratio in humans.

#jgshare

Neanderthal Dentistry: "tooth’s hollow had been scooped out by a stone drill rather than by natural decay or wear"

https://archive.ph/20260519161741/https://www.nytimes.com/2026/05/19/science/neanderthal-tooth-dentistry.html#selection-4809.4-4809.93

Human teeth kind of suck*. The history of humanity could be reframed as war against dental pain.

*They haven't had much time to evolve to match agriculture.

#jgshare

Is Sociology Salvageable?

https://jamesgmartin.center/2026/02/is-sociology-salvageable/

I am quite sad about the state of modern sociology. Until I took a 2026 undergrad sociology classI had not understood the 20th century rejection of falsifiability and science. Sociology became a kind of philosophical/legal discourse that is very valuable but inadequate. Sociology drifted into competing evidence-limited narratives that resemble medieval theology.

I came across this piece while exploring for any signs of rebuilding.

#jgshare

“Experts say fraud in federal programs is a real problem but that it is carried out primarily by transnational criminal organizations, not by individual recipients”

https://heathercoxrichardson.substack.com/p/may-14-2026

Imagine a world where expertise had a voice

#jgshare

Vibecession: “one conclusion from that is that people aren’t thinking about the economy rationally anymore. But another conclusion is that they’re thinking about the economy differently than they have been previously”

https://paulkrugman.substack.com/p/g-elliott-morris-on-vibes-and-the

A solid discussion with hypotheses. Previously good models of consumer sentiment don’t work. Everything is irrational — but maybe consumers are not entirely crazy?

#jgshare

King Trump seizes assets of the peasants: “With the announcement of the agreement, the Treasury Department’s top lawyer, Brian Morrissey, resigned.”

https://heathercoxrichardson.substack.com/p/may-19-2026

Another name to add to the hall of honor in former Trump ballroom

#jgshare

Ask Jeeves Shuts Down

https://mjtsai.com/blog/2026/05/08/ask-jeeves-shuts-down/

I remember when it was hot. Of course we are all surprised it was around at all

#jgshare

A moment in the chaos times: ChatGPT "malware" and Perplexity ai support disaster

https://notes.kateva.org/2026/05/a-moment-in-chaos-times-chatgpt-malware.html

"I think what happened here is that Perplexity Pro Support ai treated a feedback complaint as a request for action and automatically invoked a part of their content transfer hack."

Be very careful what you say to an ai support agent. They may have a lot of power to make bad mistakes. (Or it may all be coincidence. Who can say any more?)

#jgshare

“Data center land use issues are fake”

https://blog.andymasley.com/p/data-center-land-use-issues-are-fake

Good point that farming is quite toxic.

#jgshare

Body Dysmorphic Disorder: “… fixate on perceived cosmetic problems that to others appear unnoticeable … feel extreme anguish that impairs their functioning”

https://www.nytimes.com/2026/05/08/well/mind/body-dysmorphic-disorder-bdd-symptoms.html

It’s a form of delusional disorder with OCD features.

“across a patient’s life span, about 66 percent of those with B.D.D. will have thoughts of suicide and around 35 percent will attempt it.”

#jgshare

“singing mice had approximately three times the number of neurons sending signals from the motor cortex to two specific downstream regions of the brain”

https://www.nytimes.com/2026/05/06/science/a-mutation-gave-humans-the-gift-of-speech-these-mice-have-it-too.html

Language features emerge in small brains without novel anatomy but through expansion of existing pathways.

I strongly suspect something like this enabled humans to read.

#jgshare

“given the structure of legal and political institutions in America, the Supreme Court must function as a kind of crypto-Super Legislature”

https://www.lawyersgunsmoneyblog.com/2026/05/the-law-question

Novel take

“All of which is a very convoluted way of saying John Roberts is either a liar or a fool. Knowing what I know about the institutions that educated him, which happens to be a lot, I’m going to go with the latter conclusion, which may be rather charitable of me”

#jgshare

“Lutnick had said he had cut all ties with Epstein in 2005 … the two maintained contact until at least 2018”

https://heathercoxrichardson.substack.com/p/may-6-2026

Only the worst of the worst work for the MAGA.

#jgshare

Ukraine 2026: “Drones are the dominant force on the lines today, causing approximately 75–80 percent of all casualties. Ukraine now has 1.3 drones at the front line for every 1 Russian drone”

https://danieldrezner.substack.com/p/ukraines-surprising-2026

I read that a lot of pre-war Russian weapons tech came from Ukraine.

#jgshare

Anthropic: “we recently made a commitment to cover any consumer electricity price increases caused by our data centers in the US.”

https://www.anthropic.com/news/higher-limits-spacex

They are not covering the CO2 externalities of Colossus however.

#jgshare

Andes Hantavirus ship update

https://www.nytimes.com/2026/05/06/world/hantavirus-cruise-ship.html?unlocked_article_code=1.gVA.4cgB.NX_7_n10l9_e&smid=url-share

It would be good to accelerate vaccine work. mRNA tech will help.

(Maybe in Canada? Spain? China?)

#jgshare

Wordpress Reader: “… use it as a [RSS] sync backend. That includes Reeder, NetNewsWire, ReadKit, lire, Unread …”

https://activitypub.blog/2026/05/05/radical-speed-month-the-reader-meets-the-fediverse/

Similar to Feedbin but they want to support AT and Fediverse as well.

#jgshare

Distillation: “Modern LLM processes could look like using a GPT API to build an initial batch of synthetic data to build a specialized small data-processing model.”

https://www.interconnects.ai/p/the-distillation-panic

I imagine how BYTE would have covered this era and I miss it again. There really has never been an adequate replacement.

#jgshare

Oman and the MAGA debacle: “…What can we do to extricate the superpower from this unwanted entanglement? ... “America’s friends have a responsibility to tell the truth.”

https://www.firewalledmedia.com/p/losing-friends-and-alienating-people-2c4

Oman keeps a low profile.

#jgshare

Another week another assassination attempt: “same people already used this exact blood-and-thunder language for the Little Mermaid casting announcement”

https://www.theringer.com/2026/04/30/national-affairs/donald-trump-white-house-correspondents-dinner-conspiracy-theories

We are so tired.

Best take on MAGA frothing and raging

#jgshare

“a fault-tolerant quantum computer able to break deployed cryptosystems ought to be possible by around 2029”

https://scottaaronson.blog/?p=9718

Something to be said for platinum bars in the home safe.

#jgshare

Dems prepare for MAGA attacks on voting

https://talkingpointsmemo.com/news/house-democrats-election-wargames-trump

“ task force has identified “about 150 threats, … each one of those we go through and we have sort of a matrix — what we think the likelihood is of this, whatever it is, happening, and then … what’s the damage that it could cause?”

#jgshare

““HD Map”. It has not only a ton more data, but centimetre level accuracy too.”

https://maphappenings.com/2025/11/06/bee-maps/

Industry guy on history and future of nav maps.

#jgshare

“World, a project designed to distinguish humans from bots using biometrics, announced strategic partnerships with Tinder, Zoom, and Docusign”

https://restofworld.org/2026/sam-altman-worldcoin-zoom-tinder-partnerships/

Send this sentence back in time.

#jgshare

Agent Memory: “agent can probably figure out how to string together all the headers to authenticate to your weird API, or you can just make a script for it and skip the LLM.”

https://timkellogg.me/blog/2026/04/27/memory-patterns

Every week a bit different.

#jgshare

“ice XXII … repeating its pattern only every 304 molecules”

https://www.quantamagazine.org/physicists-discover-the-most-complex-forms-of-ice-yet-20260427/

Surge in ice types

#jgshare

“The widow of Renee Good has asked a court to order the federal government to hand over the vehicle her spouse was driving when she was fatally shot by an immigration agent in January.”

https://www.startribune.com/renee-goods-widow-asks-feds-to-hand-over-vehicle-late-wife-was-driving-during-fatal-ice-shooting/601804458

Feds not doing any investigation but holding on to the property anyway to block state investigations.

#jgshare

Cardiac cancer rare because of Nesprin-2

https://www.science.org/content/blog-post/no-heart-cancer-there-s-reason

Confess never occurred to me that hearts were weird in this way.

“silencing Nesprin-2 in tumor cells before those implantation experiments mentioned above led to robust tumor growth even in contracting cardiac muscle”

#jgshare

COVID becomes a cold: “patterns indicate that new strains are relatively more capable of overcoming our immune responses, but the infection outcomes are more mild”

https://www.statnews.com/2026/04/27/is-covid-still-a-thing-expert-analysis-who-needs-vaccine-booster-shot/

Immunity + virus evolution + non-exposed vulnerable are dead. Annual booster uncertain value.

Open question: do all coronaviruses cause a degree of vascular brain injury? How does that accumulate over a lifespan?

#jgshare

Yet another constitutional crisis: Congress and war.

https://www.nytimes.com/2026/04/27/opinion/trump-iran-war-powers.html

The constitution is not what it used to be.

#jgshare

He was having trouble using iOS Mail.app - creating complexity and settings.

https://www.sphone4all.com/2023/07/19/iphone-email-failures-review-your-settings/

In this case it's a lifelong cognitive disability, but it's similar for elders with acquired cognitive issues. Apps continually grow in complexity but it's often possible to reverse the complexity of Apple products in Settings. #special_needs #CognitiveDisability

#jgshare

Home sleep monitoring with Apple Watch and Google (Nest) Home Video in adult with limited ability to describe a nocturnal health issue

https://notes.kateva.org/2023/05/home-sleep-monitoring-with-apple-watch.html

Apple Watch is optional but useful. If home security cam is already purchased additional cost is most often $12-$16 but may be 0$.

#jgshare #autism #special_needs #disability

Google leak: “At the beginning of March the open source community got their hands on their first really capable foundation model, as Meta’s LLaMA was leaked to the public….”

https://www.semianalysis.com/p/google-we-have-no-moat-and-neither

“A tremendous outpouring of innovation followed … barely a month later, and there are variants with instruction tuning, quantization, quality improvements, human evals, multimodality, RLHF …”

I for one welcome. #beafraid

#jgshare

Prosumer digital image management has not progressed to our advantage

https://notes.kateva.org/2023/04/prosumer-digital-image-management-has.html

"All the options have Hotel California Syndrome -- you can check-in but you can never leave."

#datalock #aperture

#jgshare

GPT-4 gets a B on final exam for Aaronson's Introduction to Quantum Information Science. The wolf is here.

https://scottaaronson.blog/?p=7209

Without doing the course. About average for the brilliant undergrads who dare this class. Likely would do better with Mathematica plug-in.

Also got an A in Bryan Caplan's Labor Econ midterm. After losing his bet Caplan said: "AI enthusiasts have cried wolf for decades. GPT-4 is the wolf. I’ve seen it with my own eyes."

#AI #chatgpt4 #beafraid

#jgshare

ChatGPT's 155 IQ and passing the Sebastian's children puzzle

https://notes.kateva.org/2023/03/chatgpts-155-iq-and-passing-sebastians.html

I laughed and laughed but it wasn't a happy laugh. #beafraid #chatgpt

#jgshare

I ask ChatGPT about the next step: NLP and domain-specific knowledge modules.

https://notes.kateva.org/2023/03/i-ask-chatgpt-about-next-step.html?m=1

A better answer than 99% of the online comments on ChatGPT.

But don’t worry. It will be fine.

#AI #beAfraid #buckleUpButterCup

#jgshare

I ask ChatGPT about the next step: NLP and domain-specific knowledge modules.

https://notes.kateva.org/2023/03/i-ask-chatgpt-about-next-step.html?m=1

A better answer than 99% of the online comments on ChatGPT.

But don’t worry. It will be fine.

#AI #beAfraid #buckleUpButterCup

#jgshare

I ask ChatGPT about the next step: NLP and domain-specific knowledge modules.

https://notes.kateva.org/2023/03/i-ask-chatgpt-about-next-step.html?m=1

A better answer than 99% of the online comments on ChatGPT.

But don’t worry. It will be fine.

#AI #beAfraid #buckleUpButterCup

#jgshare

I ask ChatGPT about the next step: NLP and domain-specific knowledge modules.

https://notes.kateva.org/2023/03/i-ask-chatgpt-about-next-step.html?m=1

A better answer than 99% of the online comments on ChatGPT.

But don’t worry. It will be fine.

#AI #beAfraid #buckleUpButterCup

#jgshare

I ask ChatGPT about the next step: NLP and domain-specific knowledge modules.

https://notes.kateva.org/2023/03/i-ask-chatgpt-about-next-step.html?m=1

A better answer than 99% of the online comments on ChatGPT.

But don’t worry. It will be fine.

#AI #beAfraid #buckleUpButterCup

#jgshare