#isogg — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #isogg, aggregated by home.social.
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“The researchers analyzed the genomes of 258 people who were buried in what are called row graves in the modern-day German states of Bavaria and Hesse, 112 of whom were interred at the Bavarian village of Altheim. Most dated to between 450 and 620 AD” #ISOGG #DNA #ancientdna #Rome
https://www.yahoo.com/news/articles/genome-study-reveals-happened-roman-150512686.html -
“As DNA analysis of the remains is ongoing, the team also continues to analyze the organic substances, including pollen, found within the sarcophagus.” #DNA #ISOGG #AncientDNA #Cerberus #geneadons
https://www.yahoo.com/news/articles/2-000-old-sarcophagus-unsealed-173100725.html
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“As DNA analysis of the remains is ongoing, the team also continues to analyze the organic substances, including pollen, found within the sarcophagus.” #DNA #ISOGG #AncientDNA #Cerberus #geneadons
https://www.yahoo.com/news/articles/2-000-old-sarcophagus-unsealed-173100725.html
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“As DNA analysis of the remains is ongoing, the team also continues to analyze the organic substances, including pollen, found within the sarcophagus.” #DNA #ISOGG #AncientDNA #Cerberus #geneadons
https://www.yahoo.com/news/articles/2-000-old-sarcophagus-unsealed-173100725.html
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“As DNA analysis of the remains is ongoing, the team also continues to analyze the organic substances, including pollen, found within the sarcophagus.” #DNA #ISOGG #AncientDNA #Cerberus #geneadons
https://www.yahoo.com/news/articles/2-000-old-sarcophagus-unsealed-173100725.html
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“The pharmacological approach in this study, however, uses a pharmacologic agent (P7C3-A20) that enables cells to maintain their proper balance of #NAD+ under conditions of otherwise overwhelming stress, without elevating NAD+ to supraphysiologic levels.” #ISOGG #DNA #geneadons https://case.edu/news/new-study-shows-alzheimers-disease-can-be-reversed-achieve-full-neurological-recovery-not-just-prevented-or-slowed-animal-models
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“By using state-of-the-art DNA techniques and newly published genomes, we were able to determine the ancestry of the Beachy Head Woman with much greater precision than before,” William reveals.” #ISOGG #DNA #AncientDNA #BeachyHeadWoman #UK #geneadons https://www.nhm.ac.uk/discover/news/2025/december/the-changing-story-beachy-head-woman.html
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Higher intake of high-fat cheese and high-fat cream was associated with a lower risk of all-cause dementia, whereas low-fat cheese. APOE ε4 status modified the association between high-fat cheese and AD. Our study's observational design limits causal inference” #ISOGG #DNA #epigenetics #dementia #geneadons #alzheimers #cheese #brie #cheddar #cognitivedecline https://www.neurology.org/doi/10.1212/WNL.0000000000214343
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“Our finding multiple high‐level and sub‐haplogroup contexts of causal mtDNA pathogenic variants in PMD patients proves that although a possible contributor, the modifying effects of haplogroup context are not a main driver of the diagnostic disparities evident for African patients.” #DNA #Haplogroup #HaplogroupL #isogg #mitochrondria #PMD #mtDNA https://pmc.ncbi.nlm.nih.gov/articles/PMC12254466/
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“Our findings raise the possibility that this delta–theta band oscillation could serve as a target engagement biomarker, but its relationship to food preoccupation warrants more controlled investigation," the authors of the study conclude. #DNA #ISOGG #mounjaro #zepbound #diabetes #tirzepetide #epigenetics
https://www.nature.com/articles/s41591-025-04035-5 -
“In individuals with adequate TRPM7 function, Mg supplementation increases the abundance of C. maltaromaticum and F. prausnitzii.” #DNA #ISOGG #epigenetics #coloncancer #colorectalcancer #magnesium #TRPM7 #geneadons
https://www.sciencedirect.com/science/article/pii/S0002916525005271?via%3Dihub -
“Researchers have linked the death of a 47-year-old man in New Jersey to alpha-gal syndrome, which usually starts with a bite from a lone star tick. The man died four hours after eating a hamburger. NBC News’ Anne Thompson.” #ISOGG #epigenetics #AlphaGal #tick #allergy #AlphaGalSyndrome #meatallergy #lonestartick #geneadons
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“The study showed a statistical association with low and high temperature exposure and increased risk of all-cause and cardiovascular death in patients with heart failure.” #DNA #ISOGG #geneadons #epigenetics
https://www.yahoo.com/news/articles/researchers-issue-warning-discovering-unexpected-010500614.html -
“The researchers hope that by targeting FTL1, future therapies may not only improve natural cognitive decline, but will also benefit people with neurodegenerative diseases.” #DNA #ISOGG #Alzheimers #epigentics #cognitivedecline #neutrites #geneadons
https://www.yahoo.com/news/articles/scientists-found-hidden-switch-brain-133000421.html
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“Depression is linked to overly rigid brain circuits that resist change, and by softening these circuits and altering how their mitochondria function, fluoxetine may create a window of plasticity or flexibility in the brain. #DNA #ISOGG #Prozac #brain #geneadons #cognitive #Epigenetics
https://www.technologynetworks.com/neuroscience/news/antidepressant-fluoxetine-promotes-brain-plasticity-in-key-cells-reshaping-their-energy-systems-405046 -
“Depression is linked to overly rigid brain circuits that resist change, and by softening these circuits and altering how their mitochondria function, fluoxetine may create a window of plasticity or flexibility in the brain. #DNA #ISOGG #Prozac #brain #geneadons #cognitive #Epigenetics
https://www.technologynetworks.com/neuroscience/news/antidepressant-fluoxetine-promotes-brain-plasticity-in-key-cells-reshaping-their-energy-systems-405046 -
“Depression is linked to overly rigid brain circuits that resist change, and by softening these circuits and altering how their mitochondria function, fluoxetine may create a window of plasticity or flexibility in the brain. #DNA #ISOGG #Prozac #brain #geneadons #cognitive #Epigenetics
https://www.technologynetworks.com/neuroscience/news/antidepressant-fluoxetine-promotes-brain-plasticity-in-key-cells-reshaping-their-energy-systems-405046 -
“Depression is linked to overly rigid brain circuits that resist change, and by softening these circuits and altering how their mitochondria function, fluoxetine may create a window of plasticity or flexibility in the brain. #DNA #ISOGG #Prozac #brain #geneadons #cognitive #Epigenetics
https://www.technologynetworks.com/neuroscience/news/antidepressant-fluoxetine-promotes-brain-plasticity-in-key-cells-reshaping-their-energy-systems-405046 -
"Furthermore, patients with RLS who were not treated with dopamine agonists tended to be at increased risk of developing Parkinson's disease, whereas those who were treated with dopamine agonists tended to be at decreased risk compared with the control group." #ISOGG #DNA #epigenetics #Parkinsons #RLS #RestlessLegsSyndrome #geneadons
https://www.sciencealert.com/restless-legs-treatment-slashes-increased-risk-of-parkinsons-disease# -
“Another mutation of a protein in the virus’s membrane improved its ability to bind to entry point receptors in human cells, making it more resilient and infectious.” #isogg #DNA #epigentics #1918Flu #geneadons #SpanishFlu
https://www.the-independent.com/news/science/spanish-flu-pandemic-origin-mystery-lungs-b2804212.html# -
“Another mutation of a protein in the virus’s membrane improved its ability to bind to entry point receptors in human cells, making it more resilient and infectious.” #isogg #DNA #epigentics #1918Flu #geneadons #SpanishFlu
https://www.the-independent.com/news/science/spanish-flu-pandemic-origin-mystery-lungs-b2804212.html# -
“Another mutation of a protein in the virus’s membrane improved its ability to bind to entry point receptors in human cells, making it more resilient and infectious.” #isogg #DNA #epigentics #1918Flu #geneadons #SpanishFlu
https://www.the-independent.com/news/science/spanish-flu-pandemic-origin-mystery-lungs-b2804212.html# -
“Another mutation of a protein in the virus’s membrane improved its ability to bind to entry point receptors in human cells, making it more resilient and infectious.” #isogg #DNA #epigentics #1918Flu #geneadons #SpanishFlu
https://www.the-independent.com/news/science/spanish-flu-pandemic-origin-mystery-lungs-b2804212.html# -
“Another mutation of a protein in the virus’s membrane improved its ability to bind to entry point receptors in human cells, making it more resilient and infectious.” #isogg #DNA #epigentics #1918Flu #geneadons #SpanishFlu
https://www.the-independent.com/news/science/spanish-flu-pandemic-origin-mystery-lungs-b2804212.html# -
New finding on #osteoporosis: “Researchers from the University of Leipzig in Germany and Shandong University in China, identified the cell receptor GPR133 (also known as ADGRD1) as being crucial to bone density, via bone-building cells called osteoblasts.” #DNA #isogg #epigenetics #geneadons https://www.sciencealert.com/new-breakthrough-to-strengthen-bones-could-reverse-osteoporosis#
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“Results from a randomized controlled trial reveal that vitamin D supplementation helps maintain telomeres, protective caps at the ends of chromosomes that shorten during aging and are linked to the development of certain diseases.” #isogg #Harvard #geneadons #dna #VITAL #vitaminD #telomeres #epigenetics https://news.harvard.edu/gazette/story/2025/05/vitamin-d-supplements-may-slow-biological-aging/
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“Results from a randomized controlled trial reveal that vitamin D supplementation helps maintain telomeres, protective caps at the ends of chromosomes that shorten during aging and are linked to the development of certain diseases.” #isogg #Harvard #geneadons #dna #VITAL #vitaminD #telomeres #epigenetics https://news.harvard.edu/gazette/story/2025/05/vitamin-d-supplements-may-slow-biological-aging/
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“Results from a randomized controlled trial reveal that vitamin D supplementation helps maintain telomeres, protective caps at the ends of chromosomes that shorten during aging and are linked to the development of certain diseases.” #isogg #Harvard #geneadons #dna #VITAL #vitaminD #telomeres #epigenetics https://news.harvard.edu/gazette/story/2025/05/vitamin-d-supplements-may-slow-biological-aging/
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“Results from a randomized controlled trial reveal that vitamin D supplementation helps maintain telomeres, protective caps at the ends of chromosomes that shorten during aging and are linked to the development of certain diseases.” #isogg #Harvard #geneadons #dna #VITAL #vitaminD #telomeres #epigenetics https://news.harvard.edu/gazette/story/2025/05/vitamin-d-supplements-may-slow-biological-aging/
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Well done study on the HAY surname! #ISOGG #DNA #FTDNA #FamilyTreeDNA #geneadons #Hay #geneticgenealogy https://www.biorxiv.org/content/10.1101/2025.07.09.664039v4.full
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“…scientists made a surprising discovery: caffeine doesn’t act on this growth switch directly. Instead, it works by activating another important system called AMPK, a cellular fuel gauge that is evolutionarily conserved in yeast and humans.” #DNA #epigenetics #coffee #ISOGG #geneadons #caffeine #AMPK #MTOR
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Have you had the Shingles vaccine? If you’ve had the Shingles vaccine (and/or RSV vax) then you may have given yourself a dementia preventative. #isogg #dna #shingles #shingrix #RSV #epigenetics #geneadons #vaccine https://www.sciencealert.com/huge-study-reveals-2-vaccines-that-appear-to-reduce-dementia-risk
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Have you had the Shingles vaccine? If you’ve had the Shingles vaccine (and/or RSV vax) then you may have given yourself a dementia preventative. #isogg #dna #shingles #shingrix #RSV #epigenetics #geneadons #vaccine https://www.sciencealert.com/huge-study-reveals-2-vaccines-that-appear-to-reduce-dementia-risk
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Have you had the Shingles vaccine? If you’ve had the Shingles vaccine (and/or RSV vax) then you may have given yourself a dementia preventative. #isogg #dna #shingles #shingrix #RSV #epigenetics #geneadons #vaccine https://www.sciencealert.com/huge-study-reveals-2-vaccines-that-appear-to-reduce-dementia-risk
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Have you had the Shingles vaccine? If you’ve had the Shingles vaccine (and/or RSV vax) then you may have given yourself a dementia preventative. #isogg #dna #shingles #shingrix #RSV #epigenetics #geneadons #vaccine https://www.sciencealert.com/huge-study-reveals-2-vaccines-that-appear-to-reduce-dementia-risk
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“B Vitamins May Halt Glaucoma Progession” - #B6 #B9 #B12 #choline #DNA #Glaucoma #epigenetics #geneadons #isogg
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“Loomans-Kropp is especially excited about the drug's potential in treating a common type of colon cancer caused by a mutated KRAS gene, which tends to be very tough to treat.” #dna #isogg #epigenetics #coloncancer #metformin #KRAS
https://www.businessinsider.com/metformin-being-studied-colon-cancer-stopping-supplement-2025-5
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“So what has to happen is that methyltransferase has to hit that site over and over and over again, and it gradually builds up methylation … and only with repeated hits from the methyltransferase do we build up enough methylation that the gene actually gets silenced.” #DNA #isogg #Epigenetics #methylation #geneadons
https://www.chemistryworld.com/news/epigenetic-editors-enter-clinical-trials/4021267.article -
“CeCe Moore uncovered genetic evidence that Jane Gates’ youngest child was fathered by Charles Wesley Kelley, a farmer. Kelley was killed at 35 years old by lightning while closing a window, according to a local paper.” #isogg #DNA #geneticgenealogy #geneadons #PBS #findingyourroots
https://www.today.com/today/amp/rcna200312 -
CeCe Moore gave a preview of this episode at #RootsTech - be sure to tune in on Tuesday. #FindingYourRoots #DNA #geneticgenealogy #isogg #DrHenryLouisGates #CeCeMoore #geneadons https://www.pbs.org/show/finding-your-roots/
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“Variation of the mitochondrial genome has been also studied as possible source of incomplete penetrance. In fact, constitutive variants defining mtDNA haplogroup J have been found to increase penetrance in families with the m.11778G>A and, more consistently, with the m.14484T>C mutations.” #dna #isogg #mtdna #mitochondrial #haplogroupj
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FINALLY! We finally may be close thanks to DNA on the identification of Jack the Ripper! #dna #isogg #jacktheripper #uk #London #igg #figg #geneticgenealogy
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Open to all to attend - the California Genealogy Symposium in San Francisco, California on February 21-22, 2025. #DNA #ISOGG #CADAR #DAR #genealogy #geneadons
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“These findings suggest that elevated Functional Impact (FI) score of mtDNA variants might contribute to premature aging in young adulthood.” #isogg #dna #epigenetics #mtDNA #mitochondrial #biologicalclock
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Check out on Google Books: “Mitochondrial disorders due to mutations in the mitochondrial genome”. #isogg #dna #mtDNA #mitochondria #genome
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“We detailed the genetic, clinical, and molecular profiles of two Han Chinese families with MDD. These families exhibited a range of depression severities and notably low penetrance of MDD. Additionally, distinctive mtDNA polymorphisms associated with haplogroups H2 were identified.” #isogg #dna #mtDNA #mitochondrial #epigenetics #geneadons
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As of 8 Jan 2025, “The Breakthrough” is currently #6 on Netflix - let’s get it to #1!!!! And don’t forget to click the double thumbs up on Netflix so they know you loved it!
“The Breakthrough” is the true story of the first murder case solved in Sweden using genetic genealogy by Peter Sjölund. #dna #isogg #igg #figg #investigativegeneticgenealogy #sweden #geneadons
https://youtu.be/dJ1hi8VAhp8?si=Y7V4TLq2RVjoeCxZ -
Looking forward to the 11th season of “Finding Your Roots” - thanks to Thomas MacEntee for compilation. #isogg #dna #findingyourroots #FYR #geneadons #HenryLouisGates
https://genealogybargains.com/finding-your-roots-season-11-schedule/
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“…~ 40% of modern Chinese are patrilineal descendants of only three super-grandfathers at that time. This observation suggests that the main patrilineal expansion in China occurred in the Neolithic Era and might be related to the development of agriculture.” #isogg #dna #populationgenetics #chinese
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“The mtDNA haplogroup D and white matter microstructure regulated the cognitive function among community-dwelling older adults.” #isogg #DNA #epigenetics #haplogroup #mtDNA #mitochondria #geneadons
https://www.sciencedirect.com/science/article/abs/pii/S0167494323002753