#isogg — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #isogg, aggregated by home.social.
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“A virus has stopped pancreatic cancer in its tracks in three people in a clinical trial in the US. Further evaluation is needed in larger trials, but the early results are encouraging, especially since only small doses of the virus were administered for initial safety testing.” #DNA #ISOGG #pancreaticcancer #epigenetics https://aacrjournals.org/mct/article/24/10_Supplement/A109/766342/Abstract-A109-Treating-pancreatic-cancer-with
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“A virus has stopped pancreatic cancer in its tracks in three people in a clinical trial in the US. Further evaluation is needed in larger trials, but the early results are encouraging, especially since only small doses of the virus were administered for initial safety testing.” #DNA #ISOGG #pancreaticcancer #epigenetics https://aacrjournals.org/mct/article/24/10_Supplement/A109/766342/Abstract-A109-Treating-pancreatic-cancer-with
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“The researchers analyzed the genomes of 258 people who were buried in what are called row graves in the modern-day German states of Bavaria and Hesse, 112 of whom were interred at the Bavarian village of Altheim. Most dated to between 450 and 620 AD” #ISOGG #DNA #ancientdna #Rome
https://www.yahoo.com/news/articles/genome-study-reveals-happened-roman-150512686.html -
“The researchers analyzed the genomes of 258 people who were buried in what are called row graves in the modern-day German states of Bavaria and Hesse, 112 of whom were interred at the Bavarian village of Altheim. Most dated to between 450 and 620 AD” #ISOGG #DNA #ancientdna #Rome
https://www.yahoo.com/news/articles/genome-study-reveals-happened-roman-150512686.html -
A new case series from the U.K. National Prion Clinic bolstered earlier findings that suggested Alzheimer's disease could be transmitted through specific medical treatments involving contaminated biological materials. #alzheimers #dna #isogg https://www.medpagetoday.com/neurology/alzheimersdisease/120562
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A new case series from the U.K. National Prion Clinic bolstered earlier findings that suggested Alzheimer's disease could be transmitted through specific medical treatments involving contaminated biological materials. #alzheimers #dna #isogg https://www.medpagetoday.com/neurology/alzheimersdisease/120562
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“As DNA analysis of the remains is ongoing, the team also continues to analyze the organic substances, including pollen, found within the sarcophagus.” #DNA #ISOGG #AncientDNA #Cerberus #geneadons
https://www.yahoo.com/news/articles/2-000-old-sarcophagus-unsealed-173100725.html
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“As DNA analysis of the remains is ongoing, the team also continues to analyze the organic substances, including pollen, found within the sarcophagus.” #DNA #ISOGG #AncientDNA #Cerberus #geneadons
https://www.yahoo.com/news/articles/2-000-old-sarcophagus-unsealed-173100725.html
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“As DNA analysis of the remains is ongoing, the team also continues to analyze the organic substances, including pollen, found within the sarcophagus.” #DNA #isogg #ancientdna #egypt https://www.yahoo.com/news/articles/2-000-old-sarcophagus-unsealed-173100725.html
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“As DNA analysis of the remains is ongoing, the team also continues to analyze the organic substances, including pollen, found within the sarcophagus.” #DNA #isogg #ancientdna #egypt https://www.yahoo.com/news/articles/2-000-old-sarcophagus-unsealed-173100725.html
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“Beyond its oral pathogenicity, F. nucleatum has been linked to various systemic infections, including appendicitis, chorioamnionitis, osteomyelitis, pericarditis, and brain abscesses.” #ISOGG #DNA #epigenetics #colorectalcancer #cancer
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“Beyond its oral pathogenicity, F. nucleatum has been linked to various systemic infections, including appendicitis, chorioamnionitis, osteomyelitis, pericarditis, and brain abscesses.” #ISOGG #DNA #epigenetics #colorectalcancer #cancer
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“The pharmacological approach in this study, however, uses a pharmacologic agent (P7C3-A20) that enables cells to maintain their proper balance of #NAD+ under conditions of otherwise overwhelming stress, without elevating NAD+ to supraphysiologic levels.” #ISOGG #DNA #geneadons https://case.edu/news/new-study-shows-alzheimers-disease-can-be-reversed-achieve-full-neurological-recovery-not-just-prevented-or-slowed-animal-models
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“The pharmacological approach in this study, however, uses a pharmacologic agent (P7C3-A20) that enables cells to maintain their proper balance of #NAD+ under conditions of otherwise overwhelming stress, without elevating NAD+ to supraphysiologic levels.” #ISOGG #DNA #geneadons https://case.edu/news/new-study-shows-alzheimers-disease-can-be-reversed-achieve-full-neurological-recovery-not-just-prevented-or-slowed-animal-models
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“By using state-of-the-art DNA techniques and newly published genomes, we were able to determine the ancestry of the Beachy Head Woman with much greater precision than before,” William reveals.” #ISOGG #DNA #AncientDNA #BeachyHeadWoman #UK #geneadons https://www.nhm.ac.uk/discover/news/2025/december/the-changing-story-beachy-head-woman.html
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“By using state-of-the-art DNA techniques and newly published genomes, we were able to determine the ancestry of the Beachy Head Woman with much greater precision than before,” William reveals.” #ISOGG #DNA #AncientDNA #BeachyHeadWoman #UK #geneadons https://www.nhm.ac.uk/discover/news/2025/december/the-changing-story-beachy-head-woman.html
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“If these efforts manage to pinpoint Leonardo’s Y chromosome, its sequence would become the project’s genomic ground truth. DNA recovered from other sources—such as works of art—could be measured against it, providing a powerful tool for authentication. It might also unlock genetic clues to Leonardo’s genius.” #leonardodavinci #DNA #ISOGG https://www.science.org/content/article/have-scientists-found-leonardo-da-vinci-s-dna
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“If these efforts manage to pinpoint Leonardo’s Y chromosome, its sequence would become the project’s genomic ground truth. DNA recovered from other sources—such as works of art—could be measured against it, providing a powerful tool for authentication. It might also unlock genetic clues to Leonardo’s genius.” #leonardodavinci #DNA #ISOGG https://www.science.org/content/article/have-scientists-found-leonardo-da-vinci-s-dna
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Higher intake of high-fat cheese and high-fat cream was associated with a lower risk of all-cause dementia, whereas low-fat cheese. APOE ε4 status modified the association between high-fat cheese and AD. Our study's observational design limits causal inference” #ISOGG #DNA #epigenetics #dementia #geneadons #alzheimers #cheese #brie #cheddar #cognitivedecline https://www.neurology.org/doi/10.1212/WNL.0000000000214343
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Higher intake of high-fat cheese and high-fat cream was associated with a lower risk of all-cause dementia, whereas low-fat cheese. APOE ε4 status modified the association between high-fat cheese and AD. Our study's observational design limits causal inference” #ISOGG #DNA #epigenetics #dementia #geneadons #alzheimers #cheese #brie #cheddar #cognitivedecline https://www.neurology.org/doi/10.1212/WNL.0000000000214343
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“We discovered 3 regions of the genome carrying distinct DNA methylation profiles in sperm from individuals with history of childhood psychological stress, notably at proximity of genes regulating the development of the central nervous system.” #ISOGG #DNA #epigenetics https://www.nature.com/articles/s41380-024-02872-3
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“We discovered 3 regions of the genome carrying distinct DNA methylation profiles in sperm from individuals with history of childhood psychological stress, notably at proximity of genes regulating the development of the central nervous system.” #ISOGG #DNA #epigenetics https://www.nature.com/articles/s41380-024-02872-3
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“Our finding multiple high‐level and sub‐haplogroup contexts of causal mtDNA pathogenic variants in PMD patients proves that although a possible contributor, the modifying effects of haplogroup context are not a main driver of the diagnostic disparities evident for African patients.” #DNA #Haplogroup #HaplogroupL #isogg #mitochrondria #PMD #mtDNA https://pmc.ncbi.nlm.nih.gov/articles/PMC12254466/
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“Our finding multiple high‐level and sub‐haplogroup contexts of causal mtDNA pathogenic variants in PMD patients proves that although a possible contributor, the modifying effects of haplogroup context are not a main driver of the diagnostic disparities evident for African patients.” #DNA #Haplogroup #HaplogroupL #isogg #mitochrondria #PMD #mtDNA https://pmc.ncbi.nlm.nih.gov/articles/PMC12254466/
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“Our findings raise the possibility that this delta–theta band oscillation could serve as a target engagement biomarker, but its relationship to food preoccupation warrants more controlled investigation," the authors of the study conclude. #DNA #ISOGG #mounjaro #zepbound #diabetes #tirzepetide #epigenetics
https://www.nature.com/articles/s41591-025-04035-5 -
“Our findings raise the possibility that this delta–theta band oscillation could serve as a target engagement biomarker, but its relationship to food preoccupation warrants more controlled investigation," the authors of the study conclude. #DNA #ISOGG #mounjaro #zepbound #diabetes #tirzepetide #epigenetics
https://www.nature.com/articles/s41591-025-04035-5 -
“In individuals with adequate TRPM7 function, Mg supplementation increases the abundance of C. maltaromaticum and F. prausnitzii.” #DNA #ISOGG #epigenetics #coloncancer #colorectalcancer #magnesium #TRPM7 #geneadons
https://www.sciencedirect.com/science/article/pii/S0002916525005271?via%3Dihub -
“In individuals with adequate TRPM7 function, Mg supplementation increases the abundance of C. maltaromaticum and F. prausnitzii.” #DNA #ISOGG #epigenetics #coloncancer #colorectalcancer #magnesium #TRPM7 #geneadons
https://www.sciencedirect.com/science/article/pii/S0002916525005271?via%3Dihub -
“Researchers have linked the death of a 47-year-old man in New Jersey to alpha-gal syndrome, which usually starts with a bite from a lone star tick. The man died four hours after eating a hamburger. NBC News’ Anne Thompson.” #ISOGG #epigenetics #AlphaGal #tick #allergy #AlphaGalSyndrome #meatallergy #lonestartick #geneadons
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“Researchers have linked the death of a 47-year-old man in New Jersey to alpha-gal syndrome, which usually starts with a bite from a lone star tick. The man died four hours after eating a hamburger. NBC News’ Anne Thompson.” #ISOGG #epigenetics #AlphaGal #tick #allergy #AlphaGalSyndrome #meatallergy #lonestartick #geneadons
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“The study showed a statistical association with low and high temperature exposure and increased risk of all-cause and cardiovascular death in patients with heart failure.” #DNA #ISOGG #geneadons #epigenetics
https://www.yahoo.com/news/articles/researchers-issue-warning-discovering-unexpected-010500614.html -
“The study showed a statistical association with low and high temperature exposure and increased risk of all-cause and cardiovascular death in patients with heart failure.” #DNA #ISOGG #geneadons #epigenetics
https://www.yahoo.com/news/articles/researchers-issue-warning-discovering-unexpected-010500614.html -
“The researchers hope that by targeting FTL1, future therapies may not only improve natural cognitive decline, but will also benefit people with neurodegenerative diseases.” #DNA #ISOGG #Alzheimers #epigentics #cognitivedecline #neutrites #geneadons
https://www.yahoo.com/news/articles/scientists-found-hidden-switch-brain-133000421.html
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“The researchers hope that by targeting FTL1, future therapies may not only improve natural cognitive decline, but will also benefit people with neurodegenerative diseases.” #DNA #ISOGG #Alzheimers #epigentics #cognitivedecline #neutrites #geneadons
https://www.yahoo.com/news/articles/scientists-found-hidden-switch-brain-133000421.html
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“Many systemic challenges to the brain can be mitigated by the phytochemical sulforaphane (SF), which is important in supporting mitochondrial function. SF or its biogenic precursor glucoraphanin, from broccoli seeds or sprouts, can confer neuroprotective and cognitive benefits via diverse physiological and biochemical mechanisms. SF is able to cross the blood–brain barrier as well as to protect it, & it mitigates the consequences of destructive neuroinflammation.” #ISOGG https://www.mdpi.com/2072-6643/17/8/1353
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“Many systemic challenges to the brain can be mitigated by the phytochemical sulforaphane (SF), which is important in supporting mitochondrial function. SF or its biogenic precursor glucoraphanin, from broccoli seeds or sprouts, can confer neuroprotective and cognitive benefits via diverse physiological and biochemical mechanisms. SF is able to cross the blood–brain barrier as well as to protect it, & it mitigates the consequences of destructive neuroinflammation.” #ISOGG https://www.mdpi.com/2072-6643/17/8/1353
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“Depression is linked to overly rigid brain circuits that resist change, and by softening these circuits and altering how their mitochondria function, fluoxetine may create a window of plasticity or flexibility in the brain. #DNA #ISOGG #Prozac #brain #geneadons #cognitive #Epigenetics
https://www.technologynetworks.com/neuroscience/news/antidepressant-fluoxetine-promotes-brain-plasticity-in-key-cells-reshaping-their-energy-systems-405046 -
“Depression is linked to overly rigid brain circuits that resist change, and by softening these circuits and altering how their mitochondria function, fluoxetine may create a window of plasticity or flexibility in the brain. #DNA #ISOGG #Prozac #brain #geneadons #cognitive #Epigenetics
https://www.technologynetworks.com/neuroscience/news/antidepressant-fluoxetine-promotes-brain-plasticity-in-key-cells-reshaping-their-energy-systems-405046 -
“The new study examined DNA from the teeth of 13 French soldiers buried during the retreat in a mass grave in Vilnius, Lithuania. (The grave was discovered during construction in 2001.)” #DNA #ISOGG #Napolean #French #geneadons
https://news.yahoo.com/articles/dna-reveals-killed-napoleons-soldiers-150000382.html -
“The new study examined DNA from the teeth of 13 French soldiers buried during the retreat in a mass grave in Vilnius, Lithuania. (The grave was discovered during construction in 2001.)” #DNA #ISOGG #Napolean #French #geneadons
https://news.yahoo.com/articles/dna-reveals-killed-napoleons-soldiers-150000382.html -
“Until causative agents are identified and diagnostic tests developed, NCGS remains a diagnosis of exclusion, requiring careful systematic evaluation.” #DNA #ISOGG #geneadons #epigenetics #gluten #FODMAPS https://www.unimelb.edu.au/newsroom/news/2025/october/gluten-sensitivity-its-not-actually-about-gluten
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“Until causative agents are identified and diagnostic tests developed, NCGS remains a diagnosis of exclusion, requiring careful systematic evaluation.” #DNA #ISOGG #geneadons #epigenetics #gluten #FODMAPS https://www.unimelb.edu.au/newsroom/news/2025/october/gluten-sensitivity-its-not-actually-about-gluten
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“Their findings suggest that Chiari Malformation Type 1, a serious and sometimes fatal neurological condition, may be linked to Neanderthal genes that entered the human gene pool through interbreeding tens of thousands of years ago.” #DNA #ISOGG #geneadons #Neanderthal #ChiariMalformationType1 #AncientDNA #epigenetics https://www.sfu.ca/sfunews/media/media-releases/2025/07/interbreeding-with-neanderthals-may-be-responsible-for-modern-da.html
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“Their findings suggest that Chiari Malformation Type 1, a serious and sometimes fatal neurological condition, may be linked to Neanderthal genes that entered the human gene pool through interbreeding tens of thousands of years ago.” #DNA #ISOGG #geneadons #Neanderthal #ChiariMalformationType1 #AncientDNA #epigenetics https://www.sfu.ca/sfunews/media/media-releases/2025/07/interbreeding-with-neanderthals-may-be-responsible-for-modern-da.html
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“The pediatric neurologist was studying whether leucovorin could help autistic children with cerebral folate deficiency — or a shortage of vitamin B9 in the brain. Researchers believe up to 70% of autistic children have antibodies that block the transport of folate into the brain, leading to these deficiencies and contributing to speech delays and behavioral challenges.” #ISOGG #DNA #autism
https://nypost.com/2025/10/14/health/my-nonverbal-autistic-son-began-speaking-at-8-with-leucovorin/ -
“The pediatric neurologist was studying whether leucovorin could help autistic children with cerebral folate deficiency — or a shortage of vitamin B9 in the brain. Researchers believe up to 70% of autistic children have antibodies that block the transport of folate into the brain, leading to these deficiencies and contributing to speech delays and behavioral challenges.” #ISOGG #DNA #autism
https://nypost.com/2025/10/14/health/my-nonverbal-autistic-son-began-speaking-at-8-with-leucovorin/ -
"Furthermore, patients with RLS who were not treated with dopamine agonists tended to be at increased risk of developing Parkinson's disease, whereas those who were treated with dopamine agonists tended to be at decreased risk compared with the control group." #ISOGG #DNA #epigenetics #Parkinsons #RLS #RestlessLegsSyndrome #geneadons
https://www.sciencealert.com/restless-legs-treatment-slashes-increased-risk-of-parkinsons-disease# -
"Furthermore, patients with RLS who were not treated with dopamine agonists tended to be at increased risk of developing Parkinson's disease, whereas those who were treated with dopamine agonists tended to be at decreased risk compared with the control group." #ISOGG #DNA #epigenetics #Parkinsons #RLS #RestlessLegsSyndrome #geneadons
https://www.sciencealert.com/restless-legs-treatment-slashes-increased-risk-of-parkinsons-disease# -
Registration ends 30 Sept 2025 for the virtual East Coast Genetic Genealogy Conference. You have until 31 Dec 2025 to watch all of the recordings. There’s an International Society of Genetic Genealogy (ISOGG) presentation where we celebrated ISOGG’s 20th year and review the history and discuss future goals. #ISOGG #DNA #ECGGC #epigenetics #ancientdna #geneticgenealogy #geneadons https://ecggc.org/
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Registration ends 30 Sept 2025 for the virtual East Coast Genetic Genealogy Conference. You have until 31 Dec 2025 to watch all of the recordings. There’s an International Society of Genetic Genealogy (ISOGG) presentation where we celebrated ISOGG’s 20th year and review the history and discuss future goals. #ISOGG #DNA #ECGGC #epigenetics #ancientdna #geneticgenealogy #geneadons https://ecggc.org/