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#ionchannels — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #ionchannels, aggregated by home.social.

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  1. P2X receptors are ATP-gated #IonChannels that are targets for treating #ChronicPain & #cough. The #cryoEM structure of the human #P2X3 receptor in complex with the negative allosteric modulator sivopixant reveals how it stabilizes inhibitory conformations of P2X3 @PLOSBiology plos.io/4vMWCvy

  2. P2X receptors are ATP-gated #IonChannels that are targets for treating #ChronicPain & #cough. The #cryoEM structure of the human #P2X3 receptor in complex with the negative allosteric modulator sivopixant reveals how it stabilizes inhibitory conformations of P2X3 @PLOSBiology plos.io/4vMWCvy

  3. P2X receptors are ATP-gated #IonChannels that are targets for treating #ChronicPain & #cough. The #cryoEM structure of the human #P2X3 receptor in complex with the negative allosteric modulator sivopixant reveals how it stabilizes inhibitory conformations of P2X3 @PLOSBiology plos.io/4vMWCvy

  4. P2X receptors are ATP-gated #IonChannels that are targets for treating #ChronicPain & #cough. The #cryoEM structure of the human #P2X3 receptor in complex with the negative allosteric modulator sivopixant reveals how it stabilizes inhibitory conformations of P2X3 @PLOSBiology plos.io/4vMWCvy

  5. P2X receptors are ATP-gated #IonChannels that are targets for treating #ChronicPain & #cough. The #cryoEM structure of the human #P2X3 receptor in complex with the negative allosteric modulator sivopixant reveals how it stabilizes inhibitory conformations of P2X3 @PLOSBiology plos.io/4vMWCvy

  6. ⚡️ How does the Hv1 proton channel conduct protons faster than diffusion should allow?

    🔗 Fluctuating hydrogen-bond network of the Hv1 ion channel. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2025.10

    📚 CSBJ: csbj.org/

    #Biophysics #ProtonChannel #MolecularDynamics #StructuralBiology #HydrogenBonding #IonChannels #ProtonTransport #Hv1

  7. ⚡️ How does the Hv1 proton channel conduct protons faster than diffusion should allow?

    🔗 Fluctuating hydrogen-bond network of the Hv1 ion channel. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2025.10

    📚 CSBJ: csbj.org/

    #Biophysics #ProtonChannel #MolecularDynamics #StructuralBiology #HydrogenBonding #IonChannels #ProtonTransport #Hv1

  8. Sounds are amplified in the ear by hair cell motility. The signal for this comes from the brain. But what if the sounds are loud enough to cause damage? Then the brain must protect the cochlea. This important work shows the major involvement of an ATP gated ion channel in this damage limitation process, P2X7. P2X channels are somewhat neglected in their physiological roles, so this role in hearing is quite fascinating!

    biorxiv.org/content/10.1101/20

    #ionchannels #physiology #hearing #electromotility

  9. Sounds are amplified in the ear by hair cell motility. The signal for this comes from the brain. But what if the sounds are loud enough to cause damage? Then the brain must protect the cochlea. This important work shows the major involvement of an ATP gated ion channel in this damage limitation process, P2X7. P2X channels are somewhat neglected in their physiological roles, so this role in hearing is quite fascinating!

    biorxiv.org/content/10.1101/20

    #ionchannels #physiology #hearing #electromotility

  10. Sounds are amplified in the ear by hair cell motility. The signal for this comes from the brain. But what if the sounds are loud enough to cause damage? Then the brain must protect the cochlea. This important work shows the major involvement of an ATP gated ion channel in this damage limitation process, P2X7. P2X channels are somewhat neglected in their physiological roles, so this role in hearing is quite fascinating!

    biorxiv.org/content/10.1101/20

    #ionchannels #physiology #hearing #electromotility

  11. Sounds are amplified in the ear by hair cell motility. The signal for this comes from the brain. But what if the sounds are loud enough to cause damage? Then the brain must protect the cochlea. This important work shows the major involvement of an ATP gated ion channel in this damage limitation process, P2X7. P2X channels are somewhat neglected in their physiological roles, so this role in hearing is quite fascinating!

    biorxiv.org/content/10.1101/20

    #ionchannels #physiology #hearing #electromotility