#internationalsocietyofgeneticgenealogy — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #internationalsocietyofgeneticgenealogy, aggregated by home.social.
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“Paleogenomics can help elucidate the genetic basis of modern diseases, including inborn errors of immunity that impair the response to infections, providing a tool for drug development.” #dna #isogg #internationalsocietyofgeneticgenealogy #ancientdna #geneadons #nature #epigenetics #paleogenomics
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“What's more, psychopathy is almost undoubtedly only partly genetic and has a lot to do with what's called "human phenotypic plasticity" – the innate ability for our genes to express differently under different circumstances.” #dna #epigenetics #isogg #InternationalSocietyOfGeneticGenealogy
#geneadon
https://www.sciencealert.com/psychopaths-appear-to-possess-a-mysterious-evolutionary-benefit/amp -
“In a study published recently in Current Biology, the researchers examined the DNA from 10 different ancient humans, which is quite a lot considering most of them date from 5,500 to 7,500 years old. These remains came from three locations in Siberia — the Altai Mountains, the Kamchatka Peninsula and the Russian Far East.” #dna #ancientDNA #isogg #InternationalSocietyOfGeneticGenealogy #geneadons
https://www.discovermagazine.com/the-sciences/genetics-reveal-movements-of-ancient-siberians -
“The plasticity of the MuSC transcriptome suggests that modulating the niche environment can be a powerful tool to restore stem cell-mediated endogenous muscle regeneration in aging. Consequently, as opposed to focusing solely.”#dna #isogg #internationalsocietyofgeneticgenealogy #geneadons #epigenetics #aging
https://www.nature.com/articles/s41467-023-36265-x -
“Getting enough sleep, exercising every day, focusing on nutrition, and managing stress can impact your child’s entire life. A recent study published in the journal “Jama Pediatrics” suggests that a mother’s anxiety from conception through the baby’s first year of life can cause deficits in cognitive, language and motor development.”
#dna #isogg #internationalsocietyofgeneticgenealogy
https://www.news4jax.com/health/2023/02/02/epigenetics-saving-new-moms-and-their-babies/ -
“The researchers also conducted a DNA analysis of tissue recovered from the remains of six people excavated from Nevalı Çori and from another nearby site. Evidence showed that genetic relationships were growing closer during the transition period, another sign that people had stopped moving around and were living near one another.” #dna #isogg #internationalsocietyofgeneticgenealogy #ancientdna
https://phys.org/news/2023-01-isotope-ancient-dna-analysis-mobility.amp -
“The researchers designed the tool say it promises to accelerate the development of gene therapies on a large scale. Illnesses including cystic fibrosis, Tay-Sachs disease, and sickle cell anemia are caused by errors in the order of DNA letters that encode the operating instructions for every human cell. “#dna #isogg #internationalsocietyofgeneticgenealogy #geneadons
#epigenetics
https://www.sciencedaily.com/releases/2023/01/230126124431.htm -
“Take a deeper look at the most recent aDNA study from Scandinavia, and see if you’re connected to any of the ancient individuals sampled.” #dna #isogg #internationalsocietyofgeneticgenealogy #geneticgenealogy #genealogy #ftdna #geneadons
#familytreedna https://blog.familytreedna.com/scandinavian-ancient-dna/ -
“In a first for the field of epigenomics, scientists at the Baylor College of Medicine (BCM) have demonstrated the feasibility of studying systemic differences in DNA methylation at the population level through a new method called target-capture bisulfite sequencing.” #dna #isogg #internationalsocietyofgeneticgenealogy #epigenomics #geneadons
#epigenetics
https://www.genengnews.com/topics/omics/baylor-study-suggests-commercial-methylation-arrays-not-ideal-for-population-epigenetics/ -
“We assigned mitochondrial haplogroups and haplotypes from the consensus sequence (q30) generated by schmutzi and the software Haplogrep (v.2.1.25; ref. 88) applying a quality threshold of 0.65. To assign Y haplogroups, we filtered the pileup from the trimmed bams for ISOGG SNPs and for every such SNP we calculated its record of being either ancestral or derived.” #dna #isogg #internationalsocietyofgeneticgenealogy #geneticgenealogy #geneadons
https://www.nature.com/articles/s41559-022-01952-3 -
Registration for RootsTech has opened! #dna #isogg #internationalsocietyofgeneticgenealogy #geneticgenealogy #genealogy #geneadons #RootsTech2023 https://www.familysearch.org/rootstech/
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“These efforts promise to greatly improve the translatability of identified key regulators and aid in the identification of bona fide targets for the future development of pharmacotherapeutics aimed at treating these disorders.” #dna #isogg #internationalsocietyofgeneticgenealogy #geneticgenealogy #genealogy #geneadons
#epigenetics
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967246/ -
“The Denisovans, who lived 30,000 to 50,000 years ago, were shown to be less sensitive to the odors that present-day humans perceive as floral, but four times better at sensing sulfur and three times better at balsamic. And they were very attuned to honey.”#dna #isogg #internationalsocietyofgeneticgenealogy #geneticgenealogy #genealogy #geneadons
#epigenetics #Denisovans #neanderthals #ancientDNA
https://phys.org/news/2023-01-ancient-humans-sensitivities.amp -
“…mice on the time-restricted diet had synchronized their gene expression with their feeding schedules. “That is important because these genes will get translated into proteins,” Deota said. “Those proteins are helping our body to anticipate that there is food coming.”#dna #isogg #internationalsocietyofgeneticgenealogy #geneticgenealogy #genealogy #geneadons
#Epigenetics
https://www.thestar.com/amp/news/canada/2023/01/07/intermittent-fasting-may-change-how-your-dna-works-new-study-finds.html -
“Roman coins found in the fort suggest its residents weren’t native to the island, according to one theory, perhaps making them targets for violence. “Were they really locals, or did they move to Scandinavia?” Götherström asks. “Now, we have the answers.” #dna #isogg #internationalsocietyofgeneticgenealogy #geneticgenealogy #geneadons #Vikings #sweden
#Scandinavia https://www.science.org/content/article/brutal-massacre-sheds-light-migration-during-viking-age -
“In summary, RSV can protect the skin from CRI by activating AMPK/SIRT7/HMGB1 axis and will not influence the curative effects of radiotherapy.”#dna #isogg #internationalsocietyofgeneticgenealogy #geneticgenealogy #geneadons
#epigenetics -
“Sequencing his DNA revealed genetic variants linked to diabetes, heart problems, and kidney disease. The variant that most intrigued Fairbanks was in a gene that has been associated with epilepsy and neurological issues.”
#dna #isogg #internationalsocietyofgeneticgenealogy #geneticgenealogy #genealogy #geneadons
#epigenetics #mendel #gregormendel
https://www.npr.org/sections/health-shots/2022/12/30/1142202365/gregor-mendel-genetics-dna-analyzed -
“Sequencing his DNA revealed genetic variants linked to diabetes, heart problems, and kidney disease. The variant that most intrigued Fairbanks was in a gene that has been associated with epilepsy and neurological issues.”
#dna #isogg #internationalsocietyofgeneticgenealogy #geneticgenealogy #genealogy #geneadons
#epigenetics #mendel #gregormendel
https://www.npr.org/sections/health-shots/2022/12/30/1142202365/gregor-mendel-genetics-dna-analyzed -
“Sequencing his DNA revealed genetic variants linked to diabetes, heart problems, and kidney disease. The variant that most intrigued Fairbanks was in a gene that has been associated with epilepsy and neurological issues.”
#dna #isogg #internationalsocietyofgeneticgenealogy #geneticgenealogy #genealogy #geneadons
#epigenetics #mendel #gregormendel
https://www.npr.org/sections/health-shots/2022/12/30/1142202365/gregor-mendel-genetics-dna-analyzed -
“Sequencing his DNA revealed genetic variants linked to diabetes, heart problems, and kidney disease. The variant that most intrigued Fairbanks was in a gene that has been associated with epilepsy and neurological issues.”
#dna #isogg #internationalsocietyofgeneticgenealogy #geneticgenealogy #genealogy #geneadons
#epigenetics #mendel #gregormendel
https://www.npr.org/sections/health-shots/2022/12/30/1142202365/gregor-mendel-genetics-dna-analyzed -
“Sequencing his DNA revealed genetic variants linked to diabetes, heart problems, and kidney disease. The variant that most intrigued Fairbanks was in a gene that has been associated with epilepsy and neurological issues.”
#dna #isogg #internationalsocietyofgeneticgenealogy #geneticgenealogy #genealogy #geneadons
#epigenetics #mendel #gregormendel
https://www.npr.org/sections/health-shots/2022/12/30/1142202365/gregor-mendel-genetics-dna-analyzed -
“The reversibility of epigenetic changes has made the epigenetic machinery an attractive target for drug development. This review summarizes the most advanced applications of epigenetic biomarkers and epigenetic drugs in the clinical setting, highlighting commercially available DNA methylation-based assays and epigenetic drugs already approved by the US Food and Drug Administration.”
#dna #isogg #internationalsocietyofgeneticgenealogy #geneadons
#epigenetics https://acsjournals.onlinelibrary.wiley.com/doi/10.3322/caac.21765 -
“…researchers at the University of Tokyo have used the chemically-synthesised, hairpin-shaped, cancer-killing DNA to target and kill human cervical cancer and breast cancer-derived cells.” #dna #isogg #internationalsocietyofgeneticgenealogy #geneticgenealogy #geneadons
#epigenetics #cancer -
The FT SNP index lists Big Y-700 SNPs that have been named by Family Tree DNA as they have been considered for inclusion to the Y chromosome haplotree.
#dna #isogg #internationalsocietyofgeneticgenealogy #geneticgenealogy #genealogy #ftdna #YSNPS #BigY #geneadons
#epigenetics https://isogg.org/wiki/FTD_SNPs_50K -
The FT SNP index lists Big Y-700 SNPs that have been named by Family Tree DNA as they have been considered for inclusion to the Y chromosome haplotree.
#dna #isogg #internationalsocietyofgeneticgenealogy #geneticgenealogy #genealogy #ftdna #YSNPS #BigY #geneadons
#epigenetics https://isogg.org/wiki/FTD_SNPs_50K -
The FT SNP index lists Big Y-700 SNPs that have been named by Family Tree DNA as they have been considered for inclusion to the Y chromosome haplotree.
#dna #isogg #internationalsocietyofgeneticgenealogy #geneticgenealogy #genealogy #ftdna #YSNPS #BigY #geneadons
#epigenetics https://isogg.org/wiki/FTD_SNPs_50K -
The FT SNP index lists Big Y-700 SNPs that have been named by Family Tree DNA as they have been considered for inclusion to the Y chromosome haplotree.
#dna #isogg #internationalsocietyofgeneticgenealogy #geneticgenealogy #genealogy #ftdna #YSNPS #BigY #geneadons
#epigenetics https://isogg.org/wiki/FTD_SNPs_50K -
“We've discovered for the first time that the drug actually works by activating the immune system, not just by inhibiting the tumor," said lead study author Dr. Joshua Meeks #bladdercancer #dna #isogg #internationalsocietyofgeneticgenealogy #geneticgenealogy #geneadons
#epigenetics -
“Thus, global hypomethylation is a shared feature of aging and malignant cells rooted in inefficient maintenance and gradual methylation loss as somatic cells accumulate divisions.”
#dna #isogg #internationalsocietyofgeneticgenealogy #geneticgenealogy #genealogy #geneadons
#epigenetics
https://www.science.org/doi/10.1126/science.abn4009 -
“In a population-representative sample of over 800 individuals born in the 1930s, we find a significant association between early-life exposure to economic conditions during the Great Depression and late-life epigenetic age acceleration as captured by the GrimAge and DunedinPoAm algorithms.” #dna #isogg #internationalsocietyofgeneticgenealogy #geneticgenealogy #genealogy #geneadons
#epigenetics
https://www.pnas.org/doi/10.1073/pnas.2208530119 -
“Vialet worked on the first two skulls, commonly referred to as Yunxian 1 and 2. However, those relics were distorted after millennia underground, whereas the third skull, Yunxian 3, is in mint condition.” #dna #isogg #internationalsocietyofgeneticgenealogy #geneticgenealogy #genealogy #geneadons #ancientDNA https://interestingengineering.com/science/a-third-skull-is-discovered-in-china-possibly-belonging-to-the-homo-erectus-species
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LEARN SOMETHING NEW EVERYDAY: “Thus, strategies aimed at compensating for changes brought about by mitoepigenetics like restoration of dysfunctional mtDNA or TFAM activity might emerge as promising preventive and therapeutic interventions for pathological conditions occurring due to exacerbated inflammation.”#dna #isogg #internationalsocietyofgeneticgenealogy #geneticgenealogy #genealogy #geneadons
#epigenetics #mtdna #cancerhttps://www.frontiersin.org/articles/10.3389/fcell.2022.929708/full
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LEARN SOMETHING NEW EVERYDAY: “Our findings show a strong association between mtDNA sub-haplogroup K and reduced risk of TIA and ischaemic stroke in the UK population.” #dna #isogg #mtdna #haplogroupk #internationalsocietyofgeneticgenealogy #geneticgenealogy #genealogy #geneadons
#epigeneticshttps://www.thelancet.com/journals/lancet/article/PIIS1474-4422(10)70083-1/fulltext