#inflammasome — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #inflammasome, aggregated by home.social.
-
`Through unbiased analyses of #RNA and protein profiles in #Inositol polyphosphate-5-phosphatase D (INPP5D) -disrupted iPSC-derived human #microglia, we find that reduction in INPP5D activity is associated with molecular profiles consistent with disrupted #autophagy and #inflammasome activation.. findings provide insights into the molecular mechanisms underlying microglia-mediated processes in #AD and highlight the inflammasome as a potential #therapeutic target`