#idsky — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #idsky, aggregated by home.social.
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So good. Have spent years fighting this fight, with hand tied behind my back by lack of great evidence. This study is going to get quoted and cited in microbiology MDTs the world over +++ #IDSky #ClinMicro #AMR
RE: https://bsky.app/profile/did:plc:klwvdtksagcziyylwqukjgal/post/3mlsq453bqk2e -
Agree re potentially practice changing. Will be interesting to see if/when its performance gets tested in identifying asymptomatic (but probably infectious) TB cases. Could have even bigger impact on transmission and lowering case numbers. #IDSky #TBSky
RE: https://bsky.app/profile/did:plc:skpxj6dpacrxznfvwrpfdiw4/post/3mkqrvxs26c2w -
Interesting description of heteroresistance to piptaz, but from a highly monitored patient in a clinical trial. And was not associated with treatment failure Most patients don't have post-antibiotic microbiology samples, so maybe this happens commonly (& inconsequentially) #IDSky #ClinMicro #UTISky
RE: https://bsky.app/profile/did:plc:l7hoy6b4k4tuwysko34jriwi/post/3mko2f3cdxc2i -
Impressive - @[email protected] now has 10,000 members worldwide! #ClinMicro #AMR #IDSky @[email protected]
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i should add, finding it was triggered by this very good commentary (with a good title) #TBSky #IDSky www.nature.com/articles/s41...
The ghost of tuberculosis past... -
I think i'd missed this. Generates many hypotheses (in my head anyway) on the biological pathways that may be underlying this increased risk of death for many years after TB diagnosis & treatmnent. #IDSky #TBSky www.nature.com/articles/s41...
Long-term risk of death after ... -
Important piece of work that guides much of our OPAT practice in UK. It's also impressive in its acceptance of the evidence. Literally the guideline for use of IV antibiotics is advocating for use of oral antibiotics instead! 👏 #IDSky #ClinMicro #AMR #OPAT
RE: https://bsky.app/profile/did:plc:l7hoy6b4k4tuwysko34jriwi/post/3mk62wkqymc27 -
Is Beacon an alternative to promed mail for outbreak news and event based surveillance? Any thoughts? #episky #idsky #outbreaks
Disease Events - BEACON -
This is why I always correct text and capitalise the word Gram! 😅🧐 #IDSky
RE: https://bsky.app/profile/did:plc:l7hoy6b4k4tuwysko34jriwi/post/3mk4nz266322k -
And yet we're all still going to do it anyway, let's be honest! 🤷♂️ #IDSky
RE: https://bsky.app/profile/did:plc:l7hoy6b4k4tuwysko34jriwi/post/3mk4eah6scs2w -
Adjunctive immunomodulation to improve outcomes from a respiratory infection! 👀 👇 #IDSky #mycoplasma
RE: https://bsky.app/profile/did:plc:6y5mosprawcpigh3h2xaq65t/post/3mjyk3qhnz227 -
A sobering but very important observation about war and antibiotic resistance #IDSky #ClinMicro #AMR
RE: https://bsky.app/profile/did:plc:l7hoy6b4k4tuwysko34jriwi/post/3mjyl3hct3k26 -
Of note, TB helps here - turnaround time not THAT fast (still 16 days from positive culture to WGS guided treatment recommendations), but it's a slow disease. Not easily applicable to all other infections #TBSky #IDSky #ESCMIDGlobal2026 (2/3)
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I need to print this and frame it in my office!!! And then look at it before I reply to some emails... 🫣😞😂 #IDSky #AcademicSky
RE: https://bsky.app/profile/did:plc:cchjsgmpzt7k2uiz3tqvscoy/post/3mjvurtobks2p -
And an excellent summary. It's all go in the world of TB treatment! #ESCMIDGlobal2026 #TBSky #IDSky
RE: https://bsky.app/profile/did:plc:dmy36y7p2lwmdc54fjis4uez/post/3mjrsbtiov22v -
Nice vision by Nicholas Paton for TB treatment in the future. 8 week oral treatment followed by long-acting injectable that could be antimicrobial +/- host-directed. Definitely a post to come back to in 5-10 years' time! #ESCMIDGlobal2026 #IDSky #TBSky
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Recent nice paper @[email protected] looked at this: radiolgical changes (not culture) in asymptomatic contacts predictive of risk of TB disease development. PET-CT best but CXR not bad and feasible. @[email protected] www.thelancet.com/journals/lan... #IDSky #TBSky #ESCMIDGlobal2026 (2/2)
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Excellent talk from Hanif Esmail on asymptomatic TB. Around half of M tuberculosis culture positive patients have no symptoms & probably contributes to transmission. Who should we offer treatment to? #TBSky #IDSky #ESCMIDGlobal2026 (1/2)
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For those that don't know (included me!), Gremubamab binds specifically to the Pseudomonas aeruginosa PcrV protein and the Psl exopolysaccharide. Both are virulence factors used for adhesion and biofilm stability. Thanks @[email protected] ! #ESCMIDGlobal2026 #IDSky #ClinMicro
RE: https://bsky.app/profile/did:plc:jh6ykfvllrvxnubjpzazm2vb/post/3mjr55jvdxc2u -
Revisiting tuberculosis diagnostics: progress, pitfalls, and future directions #IDSky #TBSky @[email protected] www.clinicalmicrobiologyandinfection.org/article/S119...
Revisiting tuberculosis diagno... -
"Among 5121 participants assessed, 1573 (30.7%) underwent DOC, of which 1502 (95.5%) were delabeled." - that's a lot of penicillin allergy mislabelling out there! 😲 However... DOC.. more likely to be prescribed penicillin and less likely WHO “Watch” or “Reserve” antibiotics #IDSky #ClinMicro #AMR
Direct Oral Challenge for Peni... -
This is wild! (please excuse pun) Large, randomized study showing that Wolbachia‑based Aedes mosquito population suppression alone can significantly reduce dengue infections in a real‑world, dense urban setting! #dengue #IDSky #singapore @[email protected] #MedSky
Dengue Suppression by Male Wol... -
Epithelial host pathogen interactions are complex! Happy to have contributed to this work, showing how mutations in Streptococcus pneumoniae biosynthesis genes results in divergent phenotyoic effects and host transcriptional responses (the bit I did!) #IDSky #immunosky @[email protected]
Disease-Attenuated Pneumococca... -
We do quite a lot of antibiotic self administration in OPAT. Massive win if it can be achieved - lower requirements on hospital / community nurses & big autonomy win for the patients and their families. #OPAT #IDSky #ClinMicro
RE: https://bsky.app/profile/did:plc:ihlofya6s7dijxbv242tjam6/post/3mhq73irnj22b -
The Widal test drives typhoid over diagnosis and, by extension, unnecessary antibiotic prescriptions. Good piece in @[email protected] #IDSky #ClinMicro #AMR
The diagnostic void: how typho... -
Wow, have never seen a case of thyroid aspergillosis!!! #IDSky
RE: https://bsky.app/profile/did:plc:ao7ykaoap23gbmrggv4ytobn/post/3mhihskl4pe2o -
Very sad reminder of the importance of getting a travel history #IDSky www.bbc.co.uk/news/article...
Barnsley rabies death could ch... -
“Chile’s achievement demonstrates that eliminating leprosy is achievable and requires building strong systems that can detect, respond to, and provide comprehensive care for people affected by the disease, including those living with chronic disabilities" #IDSky #leprosy #MedSky
Chile becomes the first countr... -
Played a small part in this cool study @[email protected]. Identifies myofibroblasts as sources of tissue damaging enzymes (MMP1) in TB granuloma, probably responding to cytokine cues from nearby macrophages. Question now is: can we target therapeutically to prevent post-TB lung damage? #TBSky #IDSky
Single-cell and spatial profil... -
Well, that was effective use of social media time! Had totally forgotten about this webinar next Monday! Look forward to hearing from @[email protected] & @[email protected] #IDSky #ClinMicro #UTISky @[email protected]
RE: https://bsky.app/profile/did:plc:iuu7h4phnqvxwkiv36wbu4ll/post/3mgakcgctmc2w -
#episky #idsky Temporal association and seasonal variation of respiratory viruses and invasive group A streptococcal infections in Western Sweden, a 15-year analysis across pre- and postpandemic periods - International Journal of Infectious Diseases www.ijidonline.com/article/S120...
Temporal association and seaso... -
#episky #idsky Temporal association and seasonal variation of respiratory viruses and invasive group A streptococcal infections in Western Sweden, a 15-year analysis across pre- and postpandemic periods - International Journal of Infectious Diseases www.ijidonline.com/article/S120...
Temporal association and seaso... -
Important letter in @[email protected] on use of cefalexin in treating pyelonephritis. Is it effective? What's the right dose? 🤷♂️ Key quote... 👉 "Critically, there are no EUCAST breakpoints for cefalexin for systemic infection including acute pyelonephritis." #IDSky #ClinMicro #AMR #UTISky
Cefalexin use in UK acute pyel... -
Plasma cell free metagenomic sequencing to predict / diagnose blood stream infections. Neat & promising observational data. Even if unsurprising, remarkable to see increased detection of microbial genomic material as diagnosis nears. @[email protected] #IDSky #ClinMicro #UTISky #MedSky
Predicting bloodstream infecti... -
This is SUCH a good point. Life now all about being peppered by 100s of parallel mini-conversations by various message platforms. In clinical space, what does this do? Can we do more things at once? Are we more distracted, and creating risk? Food for thought for all of us, not just #IDSky #MedSky
More than a message: Death by ... -
This is a very appealing meeting in Paris later this year... "The complexity of mycobacterial infections: from research to real-world impact" #EMBOComplexInfections #TBSky for the tuberculosis research, but also #NTM #Leprosy #IDSky #ImmunoSky meetings.embo.org/event/26-myc...
The complexity of mycobacteria... -
I was enjoying this bit of trivia about the origins of name sakazakii, but then the backstory on Cronos was .... 😲 #IDSky #ClinMicro
RE: https://bsky.app/profile/did:plc:ao7ykaoap23gbmrggv4ytobn/post/3mfqscw2c7v2r -
Unexpected Friday bonus - new paper out (NOT peer reviewed)! Standardised antibiotic spectrum scores to: - quantify impact of antimicrobial stewardship rounds - prioritise patients for stewardship review Co-lead @[email protected] #IDSky #AMS #ClinMicro wellcomeopenresearch.org/articles/11-...
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Cheery and scary title popped into my inbox. Not even disinfectants working?! 😨 "Molecular mechanisms of disinfectant resistance in Klebsiella pneumoniae" #ClinMicro #IDSky @[email protected] #MedSky #IPC academic.oup.com/jacamr/artic...
Molecular mechanisms of disinf... -
Gepotidacin provides #UTI symptomatic relief comparably to nitrofurantoin (in people with uncomplicated UTI in trials) #UTISky #IDSky #ClinMicro #MedSky @[email protected] academic.oup.com/cid/advance-...
Early symptom response in pati... -
The kind of question to keep Infection doctors up at night! #IDSky #AMR #ClinMicro #MedSky
RE: https://bsky.app/profile/did:plc:krpxejciqiuk7vqttm5s7doq/post/3mbnfgjettc25 -
This is an interesting scheme - making compelling journal submissions is hard, and early rejections are often met with little to no feedback. Nice to see a journal offering to make this a learning process for early career researchers. @[email protected] #IDSky #MedSky #ClinMicro #AcademicSky
RE: https://bsky.app/profile/did:plc:6peijvvlgjki2rrxitoa65sv/post/3mbi3mp6cvi2v -
Other than jumbling up what acronyms like OPAT and COPATusually stand for in my world, this was a good study with a clear, if expected, message on safety benefit of oral antibiotics. #IDSky #ClinMicro #medsky
RE: https://bsky.app/profile/did:plc:xm2upaaxj6vztbiu2tom75aq/post/3malgvkvxd22v -
I like this v much. Learning from radiation safety to minimise harm (personal & societal) of antibiotics #IDSky #MedSky #ClinMicro #AMR "ALARA in Antimicrobial Stewardship: Adapting Radiation Safety Principles to Address Antibiotic Overuse" @[email protected] academic.oup.com/cid/advance-...
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Errr... What?! Am I?! #IDSky #ClinMicro #AMR #WAAW Great doodles @[email protected] 👏
RE: https://bsky.app/profile/did:plc:gpmq5w5m7wx4cpph3yqsdhge/post/3m5wufjcpdk2g
