#idsky — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #idsky, aggregated by home.social.
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So good. Have spent years fighting this fight, with hand tied behind my back by lack of great evidence. This study is going to get quoted and cited in microbiology MDTs the world over +++ #IDSky #ClinMicro #AMR
RE: https://bsky.app/profile/did:plc:klwvdtksagcziyylwqukjgal/post/3mlsq453bqk2e -
Interesting description of heteroresistance to piptaz, but from a highly monitored patient in a clinical trial. And was not associated with treatment failure Most patients don't have post-antibiotic microbiology samples, so maybe this happens commonly (& inconsequentially) #IDSky #ClinMicro #UTISky
RE: https://bsky.app/profile/did:plc:l7hoy6b4k4tuwysko34jriwi/post/3mko2f3cdxc2i -
Impressive - @[email protected] now has 10,000 members worldwide! #ClinMicro #AMR #IDSky @[email protected]
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Important piece of work that guides much of our OPAT practice in UK. It's also impressive in its acceptance of the evidence. Literally the guideline for use of IV antibiotics is advocating for use of oral antibiotics instead! 👏 #IDSky #ClinMicro #AMR #OPAT
RE: https://bsky.app/profile/did:plc:l7hoy6b4k4tuwysko34jriwi/post/3mk62wkqymc27 -
A sobering but very important observation about war and antibiotic resistance #IDSky #ClinMicro #AMR
RE: https://bsky.app/profile/did:plc:l7hoy6b4k4tuwysko34jriwi/post/3mjyl3hct3k26 -
For those that don't know (included me!), Gremubamab binds specifically to the Pseudomonas aeruginosa PcrV protein and the Psl exopolysaccharide. Both are virulence factors used for adhesion and biofilm stability. Thanks @[email protected] ! #ESCMIDGlobal2026 #IDSky #ClinMicro
RE: https://bsky.app/profile/did:plc:jh6ykfvllrvxnubjpzazm2vb/post/3mjr55jvdxc2u -
"Among 5121 participants assessed, 1573 (30.7%) underwent DOC, of which 1502 (95.5%) were delabeled." - that's a lot of penicillin allergy mislabelling out there! 😲 However... DOC.. more likely to be prescribed penicillin and less likely WHO “Watch” or “Reserve” antibiotics #IDSky #ClinMicro #AMR
Direct Oral Challenge for Peni... -
This is wild! (please excuse pun) Large, randomized study showing that Wolbachia‑based Aedes mosquito population suppression alone can significantly reduce dengue infections in a real‑world, dense urban setting! #dengue #IDSky #singapore @[email protected] #MedSky
Dengue Suppression by Male Wol... -
We do quite a lot of antibiotic self administration in OPAT. Massive win if it can be achieved - lower requirements on hospital / community nurses & big autonomy win for the patients and their families. #OPAT #IDSky #ClinMicro
RE: https://bsky.app/profile/did:plc:ihlofya6s7dijxbv242tjam6/post/3mhq73irnj22b -
The Widal test drives typhoid over diagnosis and, by extension, unnecessary antibiotic prescriptions. Good piece in @[email protected] #IDSky #ClinMicro #AMR
The diagnostic void: how typho... -
“Chile’s achievement demonstrates that eliminating leprosy is achievable and requires building strong systems that can detect, respond to, and provide comprehensive care for people affected by the disease, including those living with chronic disabilities" #IDSky #leprosy #MedSky
Chile becomes the first countr... -
Well, that was effective use of social media time! Had totally forgotten about this webinar next Monday! Look forward to hearing from @[email protected] & @[email protected] #IDSky #ClinMicro #UTISky @[email protected]
RE: https://bsky.app/profile/did:plc:iuu7h4phnqvxwkiv36wbu4ll/post/3mgakcgctmc2w -
Important letter in @[email protected] on use of cefalexin in treating pyelonephritis. Is it effective? What's the right dose? 🤷♂️ Key quote... 👉 "Critically, there are no EUCAST breakpoints for cefalexin for systemic infection including acute pyelonephritis." #IDSky #ClinMicro #AMR #UTISky
Cefalexin use in UK acute pyel... -
Plasma cell free metagenomic sequencing to predict / diagnose blood stream infections. Neat & promising observational data. Even if unsurprising, remarkable to see increased detection of microbial genomic material as diagnosis nears. @[email protected] #IDSky #ClinMicro #UTISky #MedSky
Predicting bloodstream infecti... -
I was enjoying this bit of trivia about the origins of name sakazakii, but then the backstory on Cronos was .... 😲 #IDSky #ClinMicro
RE: https://bsky.app/profile/did:plc:ao7ykaoap23gbmrggv4ytobn/post/3mfqscw2c7v2r -
Unexpected Friday bonus - new paper out (NOT peer reviewed)! Standardised antibiotic spectrum scores to: - quantify impact of antimicrobial stewardship rounds - prioritise patients for stewardship review Co-lead @[email protected] #IDSky #AMS #ClinMicro wellcomeopenresearch.org/articles/11-...
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This is SUCH a good point. Life now all about being peppered by 100s of parallel mini-conversations by various message platforms. In clinical space, what does this do? Can we do more things at once? Are we more distracted, and creating risk? Food for thought for all of us, not just #IDSky #MedSky
More than a message: Death by ... -
Cheery and scary title popped into my inbox. Not even disinfectants working?! 😨 "Molecular mechanisms of disinfectant resistance in Klebsiella pneumoniae" #ClinMicro #IDSky @[email protected] #MedSky #IPC academic.oup.com/jacamr/artic...
Molecular mechanisms of disinf... -
This is a very appealing meeting in Paris later this year... "The complexity of mycobacterial infections: from research to real-world impact" #EMBOComplexInfections #TBSky for the tuberculosis research, but also #NTM #Leprosy #IDSky #ImmunoSky meetings.embo.org/event/26-myc...
The complexity of mycobacteria... -
Gepotidacin provides #UTI symptomatic relief comparably to nitrofurantoin (in people with uncomplicated UTI in trials) #UTISky #IDSky #ClinMicro #MedSky @[email protected] academic.oup.com/cid/advance-...
Early symptom response in pati... -
The kind of question to keep Infection doctors up at night! #IDSky #AMR #ClinMicro #MedSky
RE: https://bsky.app/profile/did:plc:krpxejciqiuk7vqttm5s7doq/post/3mbnfgjettc25 -
This is an interesting scheme - making compelling journal submissions is hard, and early rejections are often met with little to no feedback. Nice to see a journal offering to make this a learning process for early career researchers. @[email protected] #IDSky #MedSky #ClinMicro #AcademicSky
RE: https://bsky.app/profile/did:plc:6peijvvlgjki2rrxitoa65sv/post/3mbi3mp6cvi2v -
progress in science according to medieval horses: futile or feudal? Happyish New Year 👀 #MedSky #EpiSky #IDSky #publichealth #covidconscious #nursesky #ChronicIllness #Conservation #anthropocene #environment #science #AcademicSky #Eqbsky #horses #firehorse #medieval #marginalia
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progress in science according to medieval horses: futile or feudal? Happyish New Year 👀 #MedSky #EpiSky #IDSky #publichealth #covidconscious #nursesky #ChronicIllness #Conservation #anthropocene #environment #science #AcademicSky #Eqbsky #horses #firehorse #medieval #marginalia
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progress in science according to medieval horses: futile or feudal? Happyish New Year 👀 #MedSky #EpiSky #IDSky #publichealth #covidconscious #nursesky #ChronicIllness #Conservation #anthropocene #environment #science #AcademicSky #Eqbsky #horses #firehorse #medieval #marginalia
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progress in science according to medieval horses: futile or feudal? Happyish New Year 👀 #MedSky #EpiSky #IDSky #publichealth #covidconscious #nursesky #ChronicIllness #Conservation #anthropocene #environment #science #AcademicSky #Eqbsky #horses #firehorse #medieval #marginalia
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progress in science according to medieval horses: futile or feudal? Happyish New Year 👀 #MedSky #EpiSky #IDSky #publichealth #covidconscious #nursesky #ChronicIllness #Conservation #anthropocene #environment #science #AcademicSky #Eqbsky #horses #firehorse #medieval #marginalia
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Other than jumbling up what acronyms like OPAT and COPATusually stand for in my world, this was a good study with a clear, if expected, message on safety benefit of oral antibiotics. #IDSky #ClinMicro #medsky
RE: https://bsky.app/profile/did:plc:xm2upaaxj6vztbiu2tom75aq/post/3malgvkvxd22v -
Great to see this out: new IDSA guidelines on management of complicated UTI. Listened to excellent @[email protected] podcast with @[email protected] @[email protected] @[email protected] & Valéry Lavergne earlier this year explaining how it was put together! #UTISky #IDSky
Clinical Practice Guideline by... -
I like this v much. Learning from radiation safety to minimise harm (personal & societal) of antibiotics #IDSky #MedSky #ClinMicro #AMR "ALARA in Antimicrobial Stewardship: Adapting Radiation Safety Principles to Address Antibiotic Overuse" @[email protected] academic.oup.com/cid/advance-...
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Errr... What?! Am I?! #IDSky #ClinMicro #AMR #WAAW Great doodles @[email protected] 👏
RE: https://bsky.app/profile/did:plc:gpmq5w5m7wx4cpph3yqsdhge/post/3m5wufjcpdk2g -
Still trying to get my head round what this model is predicting, as usually at least some clinical information is provided with microbiology samples. #AI #IDSky #ClinMicro #UTISky #AMR @[email protected] academic.oup.com/jac/advance-...
Machine learning for personali... -
Can't say I've even ever heard of cefdinir, probably cos we can't get it. But maybe we don't want it anyway! 😉 👇 #IDSky #ClinMicro #UTISky
RE: https://bsky.app/profile/did:plc:hczgnomn6gxwalzjrskgl4hc/post/3m3vl2y7n5c2y -
This popped up in my @cmijournal.bsky.social email today. Had read but forgotten about the ImpresU study. Methenamine reduces recurrent UTI but its cessation results in a paradoxical rebound beyond control. Mechanism? 🤔 #IDSky #UTISky www.clinicalmicrobiologyandinfection.org/article/S119...
Methenamine hippurate as proph... -
Clever use of two Greek mythological metaphors to talk about cefiderocol mechanism of action and resistance. #IDSky #ClinMicro #AMR academic.oup.com/jac/advance-...
The Achilles’ heel of the Troj... -
Love this. 😍 BLING randomised trials showed benefit of continuous antibiotic infusion, and there you go, change in practice is delivered! 👏 @ics-updates.bsky.social @biainfection.bsky.social #IDSky #ClinMicro #sepsis
RE: https://bsky.app/profile/did:plc:x34ddhklxbv74q5ac2aub77f/post/3m3rfqngea22j -
At first seems like comparing apples and oranges: moxifloxacin vs vancomycin?! Results a bit surprising ("narrow spectrum" vancomycin change microbiome more), but this is just helicopter view. More broadly, 👏 to these experimental medicine approaches for discovery science #IDSky #ClinMicro #AMR
A randomized phase 1 study inv... -
Somehow forgot to share this post this week. Was fun event, well attended (70+ people!), honour to be asked to present, and expertly chaired by @anniejoseph.bsky.social Onto the next one! 👏 #IDSky #UTISky @escmid.bsky.social
RE: https://bsky.app/profile/did:plc:iuu7h4phnqvxwkiv36wbu4ll/post/3m33lim74xk27 -
Single centre, but evidence for use of metagenomics in clinical practice is building. Discrpanacy between current gold standard diagnostics is intriguing. Which is the false +ve or -ve result? Interesting to see if / how impacts clinical practice, including cost-benefit analysis #IDSky #ClinMicro
RE: https://bsky.app/profile/did:plc:yhddktxw22k3ylm2zzzwlbqt/post/3m2766mrxtc2v -
We are on to day 3 of the #IMMEM conference in Porto after some great talks and the first poster session featuring the research that's being done by our community! Today we'll be covering environmental surveillance for #ID and #AMR and how best to share pathogen data. #IDsky #clinmicro
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There's going to be more and more of this kind of stuff coming through - #AI (a.k.a. machine learning?) algorithms going up against humans. What's the gold standard though? #UTISky #IDSky academic.oup.com/cid/advance-...
Comparing generative artificia... -
Good study even if the effective intervention not intuitive at first (to me, anyway). Basically, "conditional reflex urine culturing" = not culturing urine samples with WCC <10 👉 less antibiotic use and urine culture requests overall. #IDSky #ClinMicro #AMR #MedSky #UTISky @cidjournal.bsky.social
Implementation of Diagnostic S... -
🎯 Interesting recurrent UTI study with intriguing results: Methenamine (Hiprex): - Starting 👉 ⤵️ frequency of rUTIs in older women -Stopping 👉 ⤴️ risk of UTI relapses Many questions: - mechanism? - change symptom perception? - rebound seen also in other Rx? #UTISky #IDSky @cmijournal.bsky.social
Methenamine hippurate as proph... -
V nice study this. VRE growth in gut microbiome relies on different short chain fatty acids, which are themselves modulated by antibiotic exposure. Complex but important to understand how antibiotic resistant bacteria persist in microbiome @natcomms.nature.com 🧪 #AMR #ClinMicro #IDSky #UTISky
RE: https://bsky.app/profile/did:plc:rqryxquav4uac63sfn4qdmqh/post/3ltn7s3yzz22v
Vancomycin-resistant enterococ... -
A bit similar to the way fosfomycin can be used, as in in this RCT by @marcbonten.bsky.social (2/2) #IDSky #UTISky
Fosfomycin Vs Ciprofloxacin as... -
Pivmecillinam role in treating uncomplicated UTI is established (esp for many AmpC/ ESBL bacteria). I wonder if it also has a place in pyelonephritis care. Perhaps as an oral step down once bacillary burden has fallen? (1/2) #IDSky #UTISky #MedSky #AMR
Pivmecillinam for Treatment of... -
Nice data. To me the coolest, tho also most alarming, is slope of antibiotic resistance declining over time - gradient is shallow! So that means if UTIs recur frequently, you can see how you burn through antibiotic options quickly! #UTISky #IDSky #ClinMicro #AMR academic.oup.com/jac/advance-...
