#hyperinflammation — Public Fediverse posts

"Zombie" #COVID19 fragments linger for some, causing severe disease outcomes, new research reveals

A new finding could be the reason why some people have long COVID or die from SARS-CoV-2

By Nicole Karlis
Published February 2, 2024 3:02PM (EST)

"This suggested that more serious COVID-19 outcomes are a result of these leftover fragments that are essentially overstimulating the immune system."

https://www.salon.com/2024/02/02/zombie-19-fragments-linger-for-some-causing-severe-disease-outcomes-new-research-reveals/

#LongHaul #LongHaulCovid #LongCovid #HyperInflammation #CovidIsntOver

More evidence of #trainedimmunity in #COVID19 / #SarsCoV2 infection leading to #Hyperinflammation

#immunology #virology #infectiousdiseases #IDMastodon #medicine

https://www.cell.com/cell/fulltext/S0092-8674(23)00796-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867423007961%3Fshowall%3Dtrue

Secukinumab blocks IL-17 and some evidence of efficacy in hidradenitis suppurativa in 2x RCT.

Interesting in so much this is clearly an inflammatory disease in which there is also undoubtedly an infective component.

These studies, along with efficacy of TNF blockade indicates hyperinflammation the main issue.

#immunology #inflammation #hidradenitis #IL17 #secukinumab #RCT #trial #hyperinflammation

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)00022-3/fulltext?dgcid=raven_jbs_aip_email