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#homeostasis — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #homeostasis, aggregated by home.social.

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  1. Human #EndocannabinoidSystem

    In the 1990’s, scientists discovered endocannabinoids, the natural cannabis-like molecules produced by the #humanbody. #Scientists began to realize #cannabis exerted its effects, in part, by mimicking our #endocannabinoids. It appears the main function of the endocannabinoid system is to maintain bodily #homeostasis— #biologicalharmony in response to changes in the environment.

    cannabis.semel.ucla.edu/endoca

    #Hanfwissen #Streeck #Medizin

  2. The metabokine β-aminoisobutyric acid mediates exercise performance and skeletal muscle adaptation through a PGC1α-BAIBA-PPARδ axis

    Ethical approvals This research complies with all relevant ethical regulations. Animal studies carried out in Leeds were regulated…
    #NewsBeep #News #Fitness #AU #Australia #Energymetabolism #Health #Homeostasis #HumanitiesandSocialSciences #MetabolicDiseases #multidisciplinary #Science
    newsbeep.com/au/859845/

  3. The metabokine β-aminoisobutyric acid mediates exercise performance and skeletal muscle adaptation through a PGC1α-BAIBA-PPARδ axis

    Ethical approvals This research complies with all relevant ethical regulations. Animal studies carried out in Leeds were regulated…
    #NewsBeep #News #Fitness #Energymetabolism #Health #Homeostasis #HumanitiesandSocialSciences #MetabolicDiseases #multidisciplinary #Science #UK #UnitedKingdom
    newsbeep.com/uk/742057/

  4. #Rights are the mutual agreement of all parties that no one is to be excluded from means to maintain #homeostasis, where such means exist. Eight billion is a lot of people to guarantee that to, but is still not impossible, which means some people are hoarding more resources than they can possibly need or use. Yes, it is definitely okay to tax #billionaires down to at least millionaire status, with enforcement and no loopholes. >>

    Nearly one billion people forced to use #healthcare facilities without clean #water

    independent.co.uk/news/health/

  5. It's not difficult to extrapolate from an understanding of #homeostasis as noted in individuals to population and ecological community levels. Alas, #fossilfuel companies encouraged #Lovelock and #Margulis in their #Gaia research, as it was surmised their findings would lull the general public to believe the earth would self-regulate regardless of levels of pollution. It probably did help with the propaganda.

    To maintain homeostasis, however, always requires an #EROEI. We have dysregulated the ecological homeostasis. When it costs as much to sell and ship an item as we can make from doing so, we will stop doing so. Ships, aircraft, trains, barges and trucks are vulnerable to this. WE are vulnerable to this. >>

    Homeostasis - Wikipedia

    en.wikipedia.org/wiki/Homeosta

  6. WHAT IS HOMEOSTASIS? 💎

    It’s your body quietly and intelligently trying to help you all through the day.
    Not to make you perfect.
    Not to make you special.
    Simply to return you to balance.
    Every breath.
    Every heartbeat.
    Every moment.

    Perhaps your body has been on your side all along?

    #HOMEOSTASIS #body #intelligently #perfect #special #balance #heartbeat #breath #moment #help #quietly #day

  7. I keep coming back to this relatively unknown Australian dissertation -- it's about doctor-patient relations dangerously being interfered with by penny-pinching admins (residents of Eugene, Oregon are familiar with this).

    160 pages in, he wants to discuss patient suffering as an #entropy avoidance signaling system. >>

    "Only within an arguable and extensive ontological frame can I then begin to make sense of the core question of how an administrative intervention has impacted on doctors’ perception of their relationships with patients."

    "It will be proposed in the course of this chapter that suffering in human beings, in thermodynamic terms, constitutes a rapid increase in entropy. High rates of entropy threaten the overall viability of the organism. Rapid changes in entropy activate restorative homeostatic processes which includes recruiting the help of others. States of high entropy or rapid rates of entropic increase can be ‘reversed’ (that is, suffering can be relieved) through the introduction, from external sources, of intentional non-random energy (including new information) into the human biological system."

    "Humans can signal to others that they are experiencing rapid increases in entropy (i.e. that they are suffering). In this framing, hospital Emergency Departments are places where extreme states of entropy (suffering) are concentrated as the suffering patient expresses a need for, and recruits, external inputs of restorative and transmutative energies."

    "Through the act of suffering, humans can be conceived of as being bound together ethically, in that the route of concern for the suffering of others lies in seeing this as similar to the suffering of oneself. "

    Katzir-Katchalsky is quoted: "Life is a constant struggle against the tendency to produce entropy by irreversible processes. The synthesis of large and information-rich macromolecules, the formation of intricately structured cells, the development of organisation — all these are powerful anti-entropic forces. But since there is no possibility of escaping the entropic doom imposed upon all natural phenomena under the Second Law of #thermodynamics, living organisms choose the least evil — they produce entropy at a minimal rate by maintaining a steady state."

    << #Ethics consists in readiness to serve the #homeostasis -- temporary reduction of rate of entropy -- of others.

    Wow.

    So, doctors (or anyone providing a service) address the homeostasis of clients. Management encounters institutional entropy due to energy outflow to clients, and attempts to address that. Over time, a hospital (or any institution) becomes entirely absorbed in strategies to maintain its own homeostasis and that of its upper management and the institutions and investors supplying it energy ostensibly intended to assist the clients. So there is an ethical/unethical tension built into any service system.

    Five stars for this dissertation. ⭐ ⭐ ⭐ ⭐ ⭐ >>

    The Entropy of Suffering V1.2 .pages - uws_55187.pdf

    researchers-admin.westernsydne

  8. #EndoCannabinoidSystem: “Even if you don’t consume #cannabis, the #ECS is active in your body.
    Research has linked the ECS to the following processes:
    . appetite and digestion
    . bone remodeling and growth
    . cardiovascular system function
    . chronic #pain
    . #inflammation and other immune system responses
    . learning and memory
    . liver function
    . metabolism
    . #mood
    . motor control
    . muscle formation
    . reproductive system function
    . skin and nerve function
    . #sleep
    . #stress
    All these functions help maintain #homeostasis or the stability of your internal environment. When an external cause interrupts your body’s homeostasis, such as pain from an accident or a fever, the ECS steps in to help your body recover to its normal state.”

    thecannabiscommunity.org/endoc

  9. Hay que entender la #Salud como la #Homeostasis humana perfecta, un estado #cibernético perfecto de #autoregulación y #autogestión en #retroalimentación.

    La violencia rompe ese equilibrio perfecto y por lo tanto perjudica la salud.

  10. El motor iónico de la supervivencia humana

    La presencia indispensable del cloruro de sodio en la homeostasis celular

    La sal común, o cloruro de sodio, no es un simple aditivo culinario, sino un compuesto químico fundamental cuya presencia determina la viabilidad de la vida humana. Desde una perspectiva evolutiva, los fluidos que bañan nuestras células replican la salinidad de los océanos primitivos donde se originaron los primeros organismos. Esta concentración salina es estrictamente necesaria para mantener el equilibrio osmótico, el cual regula la cantidad de agua dentro y fuera de las membranas celulares, evitando que las células colapsen o se destruyan por exceso de presión de forma irreversible.

    A nivel neurológico y muscular, los iones de sodio y cloruro actúan como los conductores de la corriente eléctrica del cuerpo. La transmisión de los impulsos nerviosos desde el cerebro hacia el resto de los órganos depende enteramente de la bomba de sodio-potasio, un mecanismo biológico que genera gradientes de carga eléctrica a través de las membranas de las neuronas. Sin la cantidad exacta de sodio en el torrente sanguíneo, el corazón perdería la capacidad mecánica de contraerse y los músculos sufrirían parálisis debido a la ausencia de estímulo eléctrico medible.

    El sistema renal trabaja de forma ininterrumpida para filtrar y mantener los niveles de este mineral en un rango homeostático preciso. Una alteración crítica por déficit, conocida médicamente como hiponatremia, provoca edema cerebral, confusión y fallos sistémicos letales, mientras que el exceso satura la capacidad de filtración y eleva la presión arterial de manera peligrosa. El cuerpo humano no puede sintetizar el sodio por sí mismo, lo que convierte la ingesta controlada de este mineral en un requerimiento biológico absoluto e incuestionable para la continuidad de las funciones vitales.

    — Aetherius Eldritch, Periodista, Locutor, podcaster y bloger del fediverso.

    #BiologiaHumana #Fisiologia #Ciencia #Homeostasis

  11. I wrote a follow-up text to my previous thinking about AI, digital civilization, and what may come after the current hype cycle.

    It is a attempt to frame AI not as a new industrial revolution, but as the final acceleration of the digital one and maybe the beginning of something more homeostatic.

    medium.com/@igisho/the-last-in

    #AI #Technology #Philosophy #DigitalCivilization #IndustrialRevolution #Homeostasis

  12. Short-term #synaptic #plasticity (#STP) transiently modulates synaptic strength based on recent activity. #ShortTermDepression #STD reduces efficacy during repeated activity, while #ShortTermFacilitation #STF can enhance responses to closely spaced #spikes. These dynamics shape #NeuralProcessing, #filtering, and synaptic #homeostasis. Here's a short #Python implementation and simulation in #NESTSimulator:

    🌍 fabriziomusacchio.com/blog/202

    #CompNeuro #Neuroscience #NeuralDynamics #TsodyksMarkramModel

  13. 🧠🎨 New paper by Meyer et al: #astrocytic #sodium #homeostasis is not uniform. Using multiphoton #FLIM in #mouse #brain slices and #invivo, they show strong #cellular and #subcellular heterogeneity in astrocytic Na⁺ levels.

    Processes contain more Na⁺ than somata, Na⁺ varies between #astrocyte branches, and distinct Na⁺/K⁺-ATPase subunit patterns help tune local K⁺ uptake and #glutamate-linked Na⁺ influx.

    🌍 doi.org/10.1038/s41467-026-734

    #Neuroscience #Astrocytes #Neurobiology #NeuralDynamics

  14. Master Index

    A guided map across physics, biology, engineering, and AI—built around a simple idea

    Persistence is not generated, but permitted.

    Systems don’t fail because they “break.”

    They fail because their boundaries were misclassified.

    Core structure
    state → constraint → resolution → persistence

    From: - Titanic / Vasa / Challenger
    – biological regulation
    – AI hallucination & drift
    – institutional collapse

    Same pattern
    only admissible states persist

    This is the interface.
    Start anywhere. Follow the path that fits.

    #HybridMind42 #BoundaryDynamics #BoundaryArchitecture #BFPF #HQP
    #Admissibility #ConstraintResolution #StateTransition #Persistence
    #ComplexSystems #SystemsThinking #StructuralAnalysis #FailureAnalysis
    #Physics #QuantumMechanics #Relativity #Lindblad #CPTP #Decoherence
    #Biology #Physiology #Adaptation #Homeostasis
    #ArtificialIntelligence #AI #LLM #AIAlignment #AIGovernance
    #InstitutionalFailure #DecisionMaking
    #Emergence #ScientificClarity

    substack.com/@hybridmind42/not

  15. `Notably, sleep deprivation, ultraviolet radiation, and mutagens increased neuronal DNA damage and sleep pressure, while spontaneous and induced sleep facilitated genome stability in both the diurnal and crepuscular cnidarians. These results suggest that DNA damage and cellular stress in simple nerve nets may have driven the evolution of sleep.`

    doi.org/10.1038/s41467-025-674

    #cnidaria #invertebrates #marineBiology #neurology #neuroscience #evolution #sleep #homeostasis

  16. Incorporating structural #plasticity in #SpikingNeuralNetworks (#SNN) enables dynamic #synaptic connectivity, reflecting the #brain's adaptability. By modeling synaptic growth and pruning based on #calcium concentration, we can simulate processes such as #learning and #MemoryFormation. In this post, I reproduce the #NESTSimulator tutorial on structural plasticity, demonstrating its impact on network stability and #homeostasis:

    🌍 fabriziomusacchio.com/blog/202

    #CompNeuro #Neuroscience #NeuralNetworks

  17. @arcadetoken oh no, it's not unusual and it's not toxic, just the opposite.

    What you're talking about is open communication.

    What you're talking about is the same thing I always try to do during interpersonal conflict.

    See, I'm a computer #programmer by trade, an engineer.

    And, like #Hemmer from #StarTrek: #StrangeNewWorlds, I see it as my role in life, my "calling", if you will, to "Fix that which is broken".

    That applies to both myself inside and problems external to me, including other people.

    The world is filled with problems to solve.

    When I see a problem presented before me, I am COMPELLED to solve it, much like an #OCD person is compelled to do... whatever it is that they are compelled to do.

    The problem is that while, yes, other people ARE problems to solve... we all have our own internal histories and traumas that have shaped who we are.

    For many of us, and perhaps it's just a part of the #humancondition, every part of us wants to FIGHT change, to even fight improvement.

    It might possibly be a part of our mental #homeostasis, it might be #identity self-preservation, but some part of us wants us to stay the same, to make no changes. Even for the better.

    So, when I reach out to try to help "fix" people, the same way I try to improve myself EVERY damn day of my life, they often and usually respond with hesitance, suspicion, and sometimes outright hostility.

    I've learned that people can only change when they WANT to change. So all you can do is hold out the olive branch of your unique perspective, and let them know that you are there IF they want to talk and help sort out their issues, and improve themselves.

    But you can't force it on people. They have to want it for themselves.

    And that's the biggest and toughest thing that I've had to learn since I was diagnosed with #aspergers twenty years ago, is that you can't "fix" everyone... most people don't WANT to be fixed.

    So, you just have to show compassion, listen to them, and wait for a moment to give a tiny bit of advice here and there to try to steer in the direction that you think would benefit them the best.

    And then... give them space. You can only show them the door, THEY are the ones that have to walk through it.

    ...is that enough hackneyed metaphors for you? 😂

  18. Twenty years of progress in human exercise metabolism research

    Hawley, J. A., Hargreaves, M., Joyner, M. J. & Zierath, J. R. Integrative biology of exercise. Cell 159,…
    #NewsBeep #News #Fitness #CA #Canada #endocrinology #energymetabolism #general #Health #Homeostasis #Medicine/PublicHealth
    newsbeep.com/ca/135327/

  19. Twenty years of progress in human exercise metabolism research

    Hawley, J. A., Hargreaves, M., Joyner, M. J. & Zierath, J. R. Integrative biology of exercise. Cell 159,…
    #NewsBeep #News #US #USA #UnitedStates #UnitedStatesOfAmerica #Fitness #endocrinology #Energymetabolism #general #Health #Homeostasis #Medicine/PublicHealth
    newsbeep.com/us/148015/

  20. How does ER #homeostasis impact #immune response activation in #plants? Bi et al. explore how ER-localized DMP2 positively regulates resistance to #Phytophthora in #potato.
    doi.org/10.1111/jipb.13876
    @wileyplantsci
    #PlantSci #JIPB #phytopathology #botany

  21. Homeostasis: your body’s natural way of staying balanced. ⚖️ It’s the science behind stress, healing, and inner harmony. Support it, and you support your health. 🧬💚
    de320.isrefer.com/go/LUYDFREE/
     
    #Homeostasis #StressRelief #HealingScience #ThinkandGrowEducation #RayBehan #Emotions #Meditation

  22. The interaction of three hormones, #TSH, #T4 and #T3, lays the foundation for #thyroid #homeostasis and its #allostatic responses.

    It is necessary to forgo a univariable sight and to consider the evolution of the multihormonal working point to understand health and disease.

    doi.org/10.1007/978-981-96-368

  23. Multiple feedforward motifs and feedback loops maintain #thyroid #homeostasis and #allostasis. The mechanism of relational stability maintains T3 in a balanced and safe range, even in conditions of declining thyroid function.

    doi.org/10.1007/978-981-96-368

  24. Relational stability is a major motif of the intertwined feedback loops of #thyroid #homeostasis. The integrated systemic roles and interdependent homeostatically regulated equilibrium of TSH, FT4 and #deiodinase​s maintains appropriate FT3 concentrations.

    doi.org/10.1007/978-981-96-368

  25. Get your Thursday off to a great start with this #OpenAccess review exploring how #hormonal #homeostasis integrates #environmental/#developmental signals to guide #carbohydrate flow in #rice grain filling and endosperm development. 🔓⬇️
    doi.org/10.1111/jipb.13904
    @wileyplantsci
    #PlantSci #CropSci #JIPB #botany

  26. ENG: Today, first saturday of May, hundreds of thousands will march not just for a plant, but for personal freedom, civil rights, a culture of peace and the right to care for people in their family/community without Big Pharma's synthetic poison. Check a science-based better #cannabis ointment recipe:

    jorge--alban--dobles-blogspot-

    ESP: Hoy, primer sábado de mayo, cientos de miles marcharán no solo por una planta, sino en defensa de libertad personal, los derechos civiles, una cultura de paz y la posibilidad de mejorar la salud de su familia/comunidad sin los venenos sintéticos de las grandes farmacéuticas. Una mejor receta de ungüento de #marihuana , respaldada por la ciencia, en:

    jorge-alban-dobles.blogspot.co

    #cannabinoid #thc #cbd #cbn #regenerativemedicine #maconha #mota #medicinal #civilrights #freedom #peace #weed #thca #marchamundialmari #mmj
    #marijuana #cannabismedicinal
    #medicalcannabis #healing #cbda
    #herbalist #healthare #healthscience
    #medical #marijuananews #marijuana #homeostasis #chemo #pharmagreed
    #endocannabinoidsystem
    #endocannabinoide #corporategreed
    #pharma #pharmaceuticals #healthcare #HealthCrisis #health
    #solarpunk #solarpunksunday
    #cannabisculture #cannabislegalisierung

  27. @RuticaCL_74 con gusto. Hay tanta desinformación intencional al respecto. Es doloroso como le meten esteroides a pacientes de dolor crónico, o como les hacen adictos a antinflamatorios no esteroideos AINS que destruyen riñones higado y corazón o a opioides super peligrosos y adictivos cuando los extractos de cannabinoides, bien usados, son analgésico de tercera línea y su dependencia es del 9%, misma que la cafeína.

    Pero también da pena ver como le toman el pelo a los pacientes con jugos de tallos y hojas de cáñamo hemp carísimos MADE IN USA... cuando la medicina completa, con todos los cannabinoides y terpenos ( como THCa y CBDa, cannabinoides crudos o ácidos que no vuelan), podría crecer en el patio de su casa.

    jorge-alban-dobles.blogspot.co

    #cannabis #marihuana #EfectoSéquito
    #marijuananews #thc #thca #cbd #cbn
    #pain #dolorcronico #chronicpain
    #healing #herbalismo #salud #cbda #regenerativemedicine #homeostasis #endocannabinoidsysten #CostaRica

  28. ENG: "Over 70% Of Studies Back Medical Cannabis In Cancer Treatment, Meta-Analysis Finds." They searched 10.000 published papers. Keep that in mind, next time you read the old " more reasearch is needed".

    forbes.com/sites/dariosabaghi/

    Here is a modern proven anti-cancer protocol. Nothing for sale. Strictly educational: jorge--alban--dobles-blogspot-

    ESP: "Meta análisis de 10.000 estudios científicos publicados reveló una tendencia significativa ( 71.4%) que apoya el potencial terapéutico del cannabis, en particular para el manejo de los síntomas relacionados con el cáncer y efectos anticancerígenos directos."

    Enlace autotraducido:
    www-forbes-com.translate.goog/

    Aqui tienen un artículo entero con un protocolo anticancerígena actual. Nada a la venta. Fin exclusivamente educativo: jorge-alban-dobles.blogspot.co

    #cancer #Cannabinoids #medicine
    #marijuana #cannabismedicinal
    #medicalcannabis #healing #cbda #chemotherapy #cbd #quimioterapia
    #thc #thca #regenerativemedicine
    #herbalist #healthare #healthscience
    #medical #marijuananews #cbn #homeostasis #chemo #pharmagreed
    #endocannabinoidsystem #weed
    #endocannabinoide #marihuana
    #pharma #pharmaceuticals #healthcare #HealthCrisis #health

    Edited for for links to new cancer article on my blog

  29. Ever wonder how ER #homeostasis impacts #immune response activation in #plants? Look no further!
    Bi et al. report that the ER-localized DMP2 positively regulates resistance to #Phytophthora in #potato.
    doi.org/10.1111/jipb.13876
    @wileyplantsci
    #PlantSci #JIPB #phytopathology #botany

  30. Multiple studies have proven the impact of #endocrine #disruptor​s, e.g. #phthalates and #parabens, on #thyroid #homeostasis. It was unknown, however, that these effects depend on whether or not the included persons are fasting.

    pubmed.ncbi.nlm.nih.gov/398266

    doi.org/10.1016/j.envres.2025.

  31. This fundamental study looks at the role of Ezrin, a membrane-actin linker that assembles signalling complexes, unveiling a critical endosome–lysosome network essential for #autophagy and cellular #homeostasis.
    elifesciences.org/articles/985

  32. Dependre

    Quan vaig començar, creia que el millor camí era deixar sempre actuar el metge interior, la Força Vital de l'organisme; sempre amb les mínimes intervencions externes.
    Creia que no aconseguir que aquesta funcionés sense ajuda, és a dir, no assolir la curació total, era un fracàs.
    Però tot el què he tingut la sort d'anar aprenent m'ha anat allunyant d'aquest tipus de raonaments i m'ha mostrat la seva relació amb l'individualisme que ens està devastant.

    Si el món és un súperorganisme (un holobiont, de fet) i nosaltres en som parts, la Força Vital i curativa d'un remei ens pertany i en dependrem tant com de la que resideix dins nostre.

    I aleshores...
    ✨Haver-se d'acompanyar, potser de per vida, d'alguna herba o altre remei, que moderi els símptomes que no podem apagar soles, potser és una condició més de la Vida. ✨
    Potser és una de les incomptables i indefugibles interdependències que la sembren.
    Inevitable, just, bonic, enriquidor, inefable.

    I si evitant-ho estiguéssim defugint una de les relacions més profundes que existeixen?

    NO SOM INDIVIDUS.
    Recorda-ho.
    Gaudeix-ho.

    Explicaré coses sobre les plantes silvestres, les seves virtuts i els nostres vincles a les sortides de reconeixement:
    🥗Silvestres i comestibles 09/03
    🌱Els dons vegetals 13/04
    🥗Silvestres i comestibles 18/05
    🌱Els dons vegetals 08/05
    20€ (Priorat)

    T'hi pots apuntar a l'agenda de la web.

    jardidelesbruixes.cat/agenda
    #vismedicatrixnaturae #forçavital #homeostasis #holobiont #superorganism #mutualaid #suportmutu #vida #gaia #prioratexperience #priorat #prioratlovers #montsant #serrademontsant #herbesremeieres #silvestres #plantessilvestres #plantessilvestrescomestibles

  33. The hazardous impact of #parabens on #thyroid #homeostasis (HPT axis) affects several elements of the feedback loop.

  34. Dysregulation of #lung epithelial #cell #homeostasis and #immunity contributes to #MERS-CoV disease #severity

    Source: BioRxIV, AbstractCoronaviruses (CoV) emerge suddenly from animal reservoirs to cause novel diseases in new hosts. Discovered in 2012, Middle East respiratory syndrome coronavirus (MERS-CoV) is endemic in camels in the Middle East and is continually causing local outbreaks and epidemics. While all three newly emerging human CoV from past 20 years…

    etidioh.wordpress.com/2024/10/

  35. Here, we display the performance of the algorithm on the DVSgesture dataset. For this gesture recognition task, the online HOTS accuracy remains close to the chance level for about 100 events. More evidence needs to be accumulated, and then the accuracy increases monotonically, outperforming the previous method after about 10.000 events (at an average of 9.3% of the number of events in the sample) :

  36. Early-career researchers can apply for a funded place at our Workshop "Immune Cell Interactions in #Development, #Homeostasis and #Immunity" organised by Philippe Bousso, Gillian Griffiths, Milka Sarris and Michael Sixt. Find out more and apply at bit.ly/4dNRIW1

    @victoralab
    #BiologistsWorkshops

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