#hif1α — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #hif1α, aggregated by home.social.
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#Glutamate dehydrogenase1 supports #HIF1α stability to promote #colorectal #tumorigenesis under #hypoxia
An siRNA screen identifies αKG metabolic enzyme #GDH1 as acetylation-dependent control factor for intestinal cancer progression
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Keisuke Shigeta et al (Keio University School of Medicine) analyze #metabolic alterations leading to #chemoresistance in #urothelial cancer #bladdercancer: #IDH2 gain-of-function independent of #mutation is responsible for #HIF1α-dependent production of respective #gemcitabine and #CDDP competitors #dCTP and #NADPH