#hidradenitis — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #hidradenitis, aggregated by home.social.
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After a long, long incubation, Dr. Dave Morales-Heil's paper is out in HGGA.
https://www.cell.com/hgg-advances/fulltext/S2666-2477(23)00019-2
The long and short of it is he found what we think is the first new gene associated with risk for hidradenitis suppurativa since the familial association with gamma-secretase genes was found > 10 years ago. And perhaps the first association with any form of HS, not just familial HS.
#Genetics #Genomics #Bioinformatics #Hidradenitis #RareVariants
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Secukinumab blocks IL-17 and some evidence of efficacy in hidradenitis suppurativa in 2x RCT.
Interesting in so much this is clearly an inflammatory disease in which there is also undoubtedly an infective component.
These studies, along with efficacy of TNF blockade indicates hyperinflammation the main issue.
#immunology #inflammation #hidradenitis #IL17 #secukinumab #RCT #trial #hyperinflammation
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Today marks the beginning of HS Awareness Week. HS (Hidradenitis Suppurativa) is a painful, debilitating skin disorder that goes severely undiagnosed--most people who have it know that they get recurring boils in sensitive areas, but have no idea why. Spread the word!