#heterocycles — Public Fediverse posts

Starting TOMORROW 📅 February 13, 2025, at 🕒 5:00 PM CET: Online #BeilsteinTalk “From drugs to #catalysts: Application of #boron #heterocycles" with Dennis G. Hall, University of Alberta.

Participation is FREE! Just register 🔗 https://www.beilstein-institut.de/en/talks/organic-chemistry-application-of-boron-heterocycles/?M=y

#BoronHeterocycles #HeterocyclicChemistry #MedicinalChemistry #DrugDiscovery #BeilsteinTalks

Coming up next week: Online #BeilsteinTalk “From drugs to #catalysts: Application of #boron #heterocycles" with Dennis G. Hall, University of Alberta.

Register for FREE! 🔗 https://www.beilstein-institut.de/en/talks/organic-chemistry-application-of-boron-heterocycles/?M=y

#BoronHeterocycles #HeterocyclicChemistry #MedicinalChemistry #DrugDiscovery #BeilsteinTalks

Save the date: 📅 Feb. 13, 2025 🕒 5–6 pm CET:
Online #BeilsteinTalk “From drugs to #catalysts: Application of #boron #heterocycles" with Dennis G. Hall, University of Alberta.

Register for FREE! 🔗 https://www.beilstein-institut.de/en/talks/organic-chemistry-application-of-boron-heterocycles/?M=y

#BoronHeterocycles #HeterocyclicChemistry #MedicinalChemistry #DrugDiscovery #BeilsteinTalks

New Tetracyclic Ring Systems Synthesized

Five new heterocyclic ring systems that could have uses in medicinal chemistry

https://www.chemistryviews.org/new-tetracyclic-ring-systems-synthesized/

#heterocycles #orgchem #chemistry #chemistryviews #chemviews

Practical Path to Dihydrobenzisoxazoles

Partial nitro reduction of methyl 2-nitrobenzoates followed by base-mediated cyclization, alkylation, and reduction gives useful bicyclic compounds

https://www.chemistryviews.org/practical-path-to-dihydrobenzisoxazoles/

#orgchem #heterocycles #chemistry #chemistryviews #chemviews

Using Skipped Enynes in [3+3] Annulations with 4-Hydroxycoumarins:
Transformation under palladium/Brønsted-acid catalysis gives fused heterocycles
https://www.chemistryviews.org/using-skipped-enynes-in-33-annulations-with-4-hydroxycoumarins/

#orgchem #heterocycles #skippedenynes #chemistry

Curious.

Missing something?

For the journal Heterocycles, CLOCKSS appears to have volume 1, no. 1 and volume 1, no. 3

but not volume 1, no. 2

Now I have to check if volume 1, no. 2 ever existed... [it seems it didn't, lol]

#Heterocycles #CLOCKSS

https://triggered.edina.clockss.org/ServeContent?issn=1881-0942&volume=1

Today's task:

download all of the Heterocycles material that has been newly made available at CLOCKSS.

I want to see:

a) if it's all there (it probably is)

b) see how much of it is grant funded research, and from which funders. I think there are lessons to be learned here for funders (and research performing orgs, and authors, and others)... but we'll start with funders

great to finally have access to it 👍

#CLOCKSS #Heterocycles

Also, 205 days is significantly longer than the contractual minimum of 183 days (six months).

Are we going to review why there was a delay of more than 3 weeks in excess of the minimum date the content could (ought?) to have been triggered-at & made available?

#CLOCKSS #Heterocycles

At least 205 continuous days where the journal was not available online, all for what... was it worth waiting that long?

Does anyone think we should wait a bit less next time this happens?

Would you wait that long if it was a journal full of cancer research?

#CLOCKSS #Heterocycles

The paywalled chemistry journal 'Heterocycles' has been continuously offline for at least 206 days now...

The CLOCKSS board, on May 29th, voted to approve the "trigger event" to make Heterocycles publicly available under a Creative Commons license on June 17th.

But it's now June 24th...

Why is CLOCKSS sitting on this? 😕
Why is CLOCKSS apparently saying nothing about this? 🤔

#Heterocycles #VanishedJournals #MysteriousSilence

Next question: who pays for CLOCKSS?

Answer: research libraries

Perhaps those libraries who pay to support the work of CLOCKSS might want to weigh-in at some point?

https://clockss.org/digital-archive-community/supporting-libraries/

#Heterocycles

I am continuing to document the inexplicable non-release of Heterocycles journal content at CLOCKSS, using the Internet Archive Wayback Machine for webpage archiving.

Demonstrable, third-party evidence that CLOCKSS did not make the journal available on any of these days.

#Heterocycles

Dr Maria Chrzanowska for instance has a solo authored article in Heterocycles, that was published in 2023. I would be super pissed-off right now if I was her...

https://www.x-mol.net/paper/article/1712328667134971904

#Heterocycles

surely the authors of papers published in 2023 will care about it? They will remember, no? Not all research is "hit n' run (away)" is it? Someone must be proud of their research?

#Heterocycles

Trying a new approach with #Heterocycles now.

I'm emailing authors who have recently (within the last 10 years) published more than 1 article in the journal, to see what they think about both the publisher taking it offline, and the inaction from CLOCKSS to remedy the situation.

#CLOCKSS #DoesAnyoneCareAboutTheAuthors?

At least 200 consecutive days now that the paywalled chemistry journal Heterocycles has been unavailable.

CLOCKSS is continuing to do... nothing 🙄

If I was in charge of CLOCKSS I would have flicked the switch a long time ago. Even the CLOCKSS board has approved it. An incredible delay & silence...

#Heterocycles

At least 194 continuous days that the journal Heterocycles has been offline. Still no sign of it at CLOCKSS 😔 https://rossmounce.co.uk/2024/06/11/time-to-update-the-clockss/

#Heterocycles

Time to update the CLOCKSS? Why hasn't Heterocycles been released yet? https://rossmounce.co.uk/2024/06/11/time-to-update-the-clockss/

cc @chartgerink @Luke_Drury

#Heterocycles #CLOCKSS #Governance #Community #ScienceAsAPublicGood

12 days later and I still have no response to my email to the executive director of CLOCKSS https://mastodon.social/@rmounce/112479570495992214

I'm now trying some of the board of directors of CLOCKSS 🤷‍♂️

#Heterocycles #WhatIsGoingOn? #AbsoluteSilence

At least 180 days now since the chemistry journal #Heterocycles went offline. CLOCKSS has a copy of it 'dark' archived, but is so far not releasing it to the public. Go to the "triggered content" page at CLOCKSS and you'll see Heterocycles is nowhere to be seen: https://clockss.org/triggered-content/

Hmmm... 🤔

#VanishedJournals

I emailed the executive director of CLOCKSS late last Friday to ask some basic questions about #Heterocycles

No reply yet, but I'm hopeful..

#CLOCKSS

TODAY: 167 days since December 1st 2023

167 days since the 'key' subscription-access chemistry journal called Heterocycles went offline.

Still no sign of it emerging anywhere online 🤷‍♂️

This is a journal of 17,000+ articles which have been cited over 164,000 times. Not some obscuro unimportant journal.

#BrokenAccess #Heterocycles

According to @crossref metadata (is.referenced.by.count), over the 17,000+ articles published in Heterocycles, collectively they have been cited over 164,000 times.

But the journal has been offline for 5.2 months now...

#Heterocycles

My daily routine:

1.) go to the CLOCKSS triggered content page: https://clockss.org/triggered-content/

2.) Ctrl+F "Heterocycles"
0/0 matches

3. ) *sigh*

Can we pretty please have access to the 17,000+ chemistry articles published in Heterocycles? Will we really have to (pointlessly) wait until June 1st 2024 before this stuff becomes available online again?

#Heterocycles #CLOCKSS

For those wondering when #CLOCKSS can open access to their copies of the chemistry journal #Heterocycles, which a number of readers have noted has been offline for a while: 6 months from the time it becomes "unavailable from any publisher", unless the publisher OKs an earlier release, per their standard publisher agreement: https://clockss.org/wp-content/uploads/2024/01/CLOCKSS-Participating-Publisher-Agreement-2024.pdf (Thanks to Grouse on Metafilter for the link to the agreement.) #preservation

It would be a lot of fun to create a chart demonstrating out of the 17,000+ vanished articles at Heterocycles, which ones were funded by e.g. NSF, BBSRC, Estonian Science Foundation, Wellcome Trust, et cetera.

Then email each of those funders asking what they think about the situation - that online access to this research they have funded has gone.

#Heterocycles #VanishedJournals #JournalFailure #CLOCKSS

Another interesting idea... what is the coverage of the vanished journal 'Heterocycles' in Sci-Hub?

Apparently only 36.7% according to the Sci-Hub Stats Browser: https://greenelab.github.io/scihub/#/journal/25864

#JournalFailure #Heterocycles #VanishingJournals #SciHub

Summarizing some of the things I've been thinking about in the last 24hrs about #Heterocycles and the poor state of scholarly communications online:

Things we can learn from the ongoing Heterocycles debacle https://rossmounce.co.uk/2024/04/11/things-we-can-learn-from-the-ongoing-heterocycles-debacle/

cc @mpe @mike @mattjhodgkinson

#CLOCKSS #DigitalPreservation #OpenAccess