Live and recent posts from across the Fediverse tagged #hepaticsteatosis, aggregated by home.social.
A mouse study found that age-related fatty liver disease is restored by the flavonoid hisperetin, which is found in citrus fruits. Hisperetin seems to act through modification of the expression of a gene that regulates liver aging.
Original paper: https://www.nature.com/articles/s41514-026-00479-2
#Science #Health #Aging #FattyLiverDisease #HepaticSteatosis
Analysis of the effect of #hepatocyte p110α deletion on metabolic homeostasis in mice reveals that PI3Kα signaling is critical for the regulation of #liver gene expression and its reprogramming in the context of #HepaticSteatosis @PLOSBiology https://plos.io/4jGLBoD
Hepatic #lipid #metabolism is regulated by the #AutonomicNervousSystem. This study shows that some #hepatocytes & cholangiocytes are innervated by branches of the vagus nerve; ablating them in mice on a high-fat diet prevents #HepaticSteatosis #PLOSBiology https://plos.io/4hdJiJp
Liver microRNA transcriptome reveals miR-182 as link between type 2 diabetes and fatty liver disease in obesity
https://www.biorxiv.org/content/10.1101/2023.10.02.560594v1?rss=1
#miRNA #microRNA #miR-182 #T2D #diabetes #FattyLiver #obesity #HepaticSteatosis #liver #CellularSignaling