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#henipavirus — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #henipavirus, aggregated by home.social.

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  1. Two Novel Henipaviruses Detected in Fruit bats in China 
    The henipaviruses, Hendra virus (HeV) and Nipah virus (NiV) are known to cause fatal diseases in humans............
    #bats #china #Fruitbats #hendravirus #henipavirus #Langyavirus #nipahvirus #Paramyxoviridae #Yunnan
    Umesh Prasad

    scientificeuropean.co.uk/medic

  2. Two Novel Henipaviruses Detected in Fruit bats in China 
    The henipaviruses, Hendra virus (HeV) and Nipah virus (NiV) are known to cause fatal diseases in humans............
    #bats #china #Fruitbats #hendravirus #henipavirus #Langyavirus #nipahvirus #Paramyxoviridae #Yunnan
    Umesh Prasad

    scientificeuropean.co.uk/medic

  3. Two Novel Henipaviruses Detected in Fruit bats in China 
    The henipaviruses, Hendra virus (HeV) and Nipah virus (NiV) are known to cause fatal diseases in humans............
    #bats #china #Fruitbats #hendravirus #henipavirus #Langyavirus #nipahvirus #Paramyxoviridae #Yunnan
    Umesh Prasad

    scientificeuropean.co.uk/medic

  4. Two Novel Henipaviruses Detected in Fruit bats in China 
    The henipaviruses, Hendra virus (HeV) and Nipah virus (NiV) are known to cause fatal diseases in humans............
    #bats #china #Fruitbats #hendravirus #henipavirus #Langyavirus #nipahvirus #Paramyxoviridae #Yunnan
    Umesh Prasad

    scientificeuropean.co.uk/medic

  5. The discovery of a #henipavirus in North America is highly significant, as it suggests these #viruses may be more globally distributed than previously thought.
    #Virology #sflorg
    sflorg.com/2025/01/vi01282501.

  6. The discovery of a #henipavirus in North America is highly significant, as it suggests these #viruses may be more globally distributed than previously thought.
    #Virology #sflorg
    sflorg.com/2025/01/vi01282501.

  7. The discovery of a #henipavirus in North America is highly significant, as it suggests these #viruses may be more globally distributed than previously thought.
    #Virology #sflorg
    sflorg.com/2025/01/vi01282501.

  8. The discovery of a #henipavirus in North America is highly significant, as it suggests these #viruses may be more globally distributed than previously thought.
    #Virology #sflorg
    sflorg.com/2025/01/vi01282501.

  9. The discovery of a #henipavirus in North America is highly significant, as it suggests these #viruses may be more globally distributed than previously thought.
    #Virology #sflorg
    sflorg.com/2025/01/vi01282501.

  10. Structural #basis of #Nipah virus #replication

    Source: BioRxIV, https://www.biorxiv.org/content/10.1101/2024.10.04.616610v1?rss=1

    Abstract
    Nipah virus (NiV) is a non-segmented negative-strand RNA virus (nsNSV) with high pandemic potential, as it frequently causes zoonotic outbreaks and can be transmitted from human to human. Its RNA-dependent RNA polymerase (RdRp) complex carries out viral genome replication and transcription and is therefore an attractive drug target. However, to date no structural data is available on the NiV RdRp complex. Here, we report cryo-EM structures of NiV RdRp in the apo and in an early elongation state with RNA and incoming substrate bound. The structure of the apo enzyme reveals the architecture of the NiV RdRp complex, which shows a high degree of similarity to other nsNSV RdRps. The structure of the RNA-bound NiV RdRp shows how the enzyme interacts with template and product RNA during early replication and how nucleoside triphosphates are bound in the active site. Comparisons show that RNA binding leads to rearrangements of key elements in the RdRp core and to ordering of the flexible C-terminal domains of NiV L required for RNA capping. Taken together, these results reveal the first structural snapshots of an actively replicating nsNSV RdRp and provide insights into the mechanisms of genome replication and transcription by NiV and related viruses.

    ____

    #abstract #biology #dna #genetics #henipavirus #nipahVirus #research #rna #science

  11. Structural #basis of #Nipah virus #replication

    Source: BioRxIV, https://www.biorxiv.org/content/10.1101/2024.10.04.616610v1?rss=1

    Abstract
    Nipah virus (NiV) is a non-segmented negative-strand RNA virus (nsNSV) with high pandemic potential, as it frequently causes zoonotic outbreaks and can be transmitted from human to human. Its RNA-dependent RNA polymerase (RdRp) complex carries out viral genome replication and transcription and is therefore an attractive drug target. However, to date no structural data is available on the NiV RdRp complex. Here, we report cryo-EM structures of NiV RdRp in the apo and in an early elongation state with RNA and incoming substrate bound. The structure of the apo enzyme reveals the architecture of the NiV RdRp complex, which shows a high degree of similarity to other nsNSV RdRps. The structure of the RNA-bound NiV RdRp shows how the enzyme interacts with template and product RNA during early replication and how nucleoside triphosphates are bound in the active site. Comparisons show that RNA binding leads to rearrangements of key elements in the RdRp core and to ordering of the flexible C-terminal domains of NiV L required for RNA capping. Taken together, these results reveal the first structural snapshots of an actively replicating nsNSV RdRp and provide insights into the mechanisms of genome replication and transcription by NiV and related viruses.

    ____

    #abstract #biology #dna #genetics #henipavirus #nipahVirus #research #rna #science

  12. RT @ECDC_Outbreaks: #JustPublished!
    #Langya #henipavirus under ECDC monitoring.

    According to a group of Chinese scientists, the detection of a previously unknown, phylogenetically distinct henipavirus, named Langya henipavirus (#LayV), was reported in China.

    ecdc.europa.eu/en/news-events/
    #Langyavirus

    🐦🔗: nitter.eu/ECDC_EU/status/15580