#hematopoieticstemcells — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #hematopoieticstemcells, aggregated by home.social.
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The #placenta has been proposed to harbor hemogenic endothelium that generates #HematopoieticStemCells (HSCs). This study tests this using lineage tracing analyses, but find no evidence that the placental vasculature is a site of de novo HSC formation #plosbiology https://plos.io/4hl3qZF
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Dormant #HematopoieticStemCells (dHSCs) are a key stem cell reserve for lifelong #hematopoiesis. This study shows that CD38 promotes dormancy in mouse HSCs; while human HSCs lack CD38, CD38 in neighboring cells similarly promotes quiescence #PLOSBiology https://plos.io/3SWi5Q5
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Deficiency of miR-221/222 lowers lymphoid multipotency & raises stress-induced #granulopoiesis, without affecting #BoneMarrow homing of #HematopoieticStemCells, suggesting that boosting miR-221/222 might improve efficacy of #transplantation #PLOSBiology https://plos.io/47mYBds